A novel aggregation induced emission active cyclometalated Ir(III) complex as a luminescent probe for detection of copper(II) ion in aqueous solution

2016 ◽  
Vol 177 ◽  
pp. 299-305 ◽  
Author(s):  
Wei Shen ◽  
Liqiang Yan ◽  
Wenwen Tian ◽  
Xia Cui ◽  
Zhengjian Qi ◽  
...  
CrystEngComm ◽  
2021 ◽  
Author(s):  
Yuanshan Xue ◽  
Ji Ding ◽  
Dan-Ling Sun ◽  
Weiwei Cheng ◽  
Xuanrong Chen ◽  
...  

Two families of lanthanide metal-organic frameworks (Ln-MOFs), namely {[Ln2L2(DMF)4]·xDMF·yH2O}n (Ln = Ce(1), Pr(2), Sm(3), Eu(4), Gd(5); x = 0,1; y = 0,1), and {[Ln2L2(H2O)2.5]}n (Ln = Dy(6), Ho(7)), have been...


2017 ◽  
Vol 196 ◽  
pp. 377-393 ◽  
Author(s):  
Danni Liu ◽  
Shenglu Ji ◽  
Heran Li ◽  
Liang Hong ◽  
Deling Kong ◽  
...  

The exploration of advanced fluorescent probes that can detect divalent copper (Cu2+) in aqueous environments and even in live organisms is particularly valuable for understanding the occurrence and development of Cu2+-related diseases. In this work, we report the design and synthesis of an aggregation-induced emission luminogen (AIEgen)-based probe (TPE-Py-EEGTIGYG) by integrating an AIEgen, TPE-Py, with a peptide, EEGTIGYG, which can selectively detect Cu2+ in both aqueous solution and live cells. Peptide EEGTIGYG has dual functionality in the probe design, namely improving water solubility and providing specific cell membrane-binding ability. TPE-Py-EEGTIGYG can self-assemble into nanoaggregates at high concentration in aqueous solution (e.g., 25 μM), which possess large fluorescence output due to the restriction of intramolecular rotation of the phenyl rings on TPE-Py. The fluorescence of the TPE-Py-EEGTIGYG nanoaggregates can be significantly quenched by Cu2+ but not by other metal ions, achieving the selective detection of Cu2+ in aqueous media. Furthermore, TPE-Py-EEGTIGYG can exist as a molecular species and is very weakly fluorescent in dilute aqueous solution (e.g., 5 μM), but can however largely switch on its fluorescence upon specifically anchoring onto the cell membrane. The emissive probes on the cell membrane can be used for the detection of Cu2+ ions that move in and out of cells with a fluorescence “turn-off” mode.


2019 ◽  
Vol 171 ◽  
pp. 107696 ◽  
Author(s):  
Hechen Wu ◽  
Hanhan Chen ◽  
Minghui Fu ◽  
Rui Li ◽  
Pengtao Ma ◽  
...  

2019 ◽  
Vol 171 ◽  
pp. 107682 ◽  
Author(s):  
Yuanyuan Li ◽  
Kui Xu ◽  
Yue Si ◽  
Cuiping Yang ◽  
Qiuchen Peng ◽  
...  

2014 ◽  
Vol 50 ◽  
pp. 31-34 ◽  
Author(s):  
Yanmeng Xiao ◽  
Yanqin Yang ◽  
Guiyan Zhao ◽  
Xinxiu Fang ◽  
Yongxia Zhao ◽  
...  

2021 ◽  
Vol 60 (6) ◽  
pp. 3667-3676
Author(s):  
Daniel Blasco ◽  
José M. López-de-Luzuriaga ◽  
Miguel Monge ◽  
M. Elena Olmos ◽  
David Pascual ◽  
...  

2019 ◽  
Vol 55 (45) ◽  
pp. 6353-6356 ◽  
Author(s):  
Chun Wu ◽  
Ke-Jia Wu ◽  
Jin-Biao Liu ◽  
Xiao-Ming Zhou ◽  
Chung-Hang Leung ◽  
...  

We have designed for the first time a dual-functional luminescent probe and inhibitor of neuraminidase (NA), a key influenza target.


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