scholarly journals Co-morbidity and blood group type risk in coronavirus disease 2019 patients: a case–control study

2021 ◽  
Author(s):  
Mohammed Badedi ◽  
Ali Makrami ◽  
Awaji Alnami
Keyword(s):  
Blood Group ◽  
Case Control Study ◽  
Case Control ◽  
Group Type ◽  
Co Morbidity ◽  
Blood Group Type ◽  
Control Study

scholarly journals Relation of severe COVID-19 to polypharmacy and prescribing of psychotropic drugs: the REACT-SCOT case-control study

BMC Medicine ◽  
2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Paul M. McKeigue ◽  
◽  
Sharon Kennedy ◽  
Amanda Weir ◽  
Jen Bishop ◽  
...  
Keyword(s):  
Primary Care ◽  
Rate Ratio ◽  
Case Control Study ◽  
Fatal Outcome ◽  
Case Control ◽  
Care Practice ◽  
Drug Classes ◽  
Increased Risk ◽  
Co Morbidity ◽  
Control Study

Abstract Background The objective of this study was to investigate the relation of severe COVID-19 to prior drug prescribing. Methods Severe cases were defined by entry to critical care or fatal outcome. For this matched case-control study (REACT-SCOT), all 4251 cases of severe COVID-19 in Scotland since the start of the epidemic were matched for age, sex and primary care practice to 36,738 controls from the population register. Records were linked to hospital discharges since June 2015 and dispensed prescriptions issued in primary care during the last 240 days. Results Severe COVID-19 was strongly associated with the number of non-cardiovascular drug classes dispensed. This association was strongest in those not resident in a care home, in whom the rate ratio (95% CI) associated with dispensing of 12 or more drug classes versus none was 10.8 (8.8, 13.3), and in those without any of the conditions designated as conferring increased risk of COVID-19. Of 17 drug classes postulated at the start of the epidemic to be “medications compromising COVID”, all were associated with increased risk of severe COVID-19 and these associations were present in those without any of the designated risk conditions. The fraction of cases in the population attributable to exposure to these drug classes was 38%. The largest effect was for antipsychotic agents: rate ratio 4.18 (3.42, 5.11). Other drug classes with large effects included proton pump inhibitors (rate ratio 2.20 (1.72, 2.83) for = 2 defined daily doses/day), opioids (3.66 (2.68, 5.01) for = 50 mg morphine equivalent/day) and gabapentinoids. These associations persisted after adjusting for covariates and were stronger with recent than with non-recent exposure. Conclusions Severe COVID-19 is associated with polypharmacy and with drugs that cause sedation, respiratory depression, or dyskinesia; have anticholinergic effects; or affect the gastrointestinal system. These associations are not easily explained by co-morbidity. Measures to reduce the burden of mortality and morbidity from COVID-19 should include reinforcing existing guidance on reducing overprescribing of these drug classes and limiting inappropriate polypharmacy. Registration ENCEPP number https://EUPAS35558

scholarly journals Frequency of Thrombotic Risk Factors in Patients with Chronic Thromboembolic Pulmonary Hypertension and Acute Pulmonary Embolism: A Case-Control Study

2022 ◽  
Vol 28 ◽  
pp. 107602962110732
Author(s):  
Mark W. Dodson ◽  
Meghan M. Cirulis ◽  
Haojia Li ◽  
Zhang Yue ◽  
Lynette M. Brown ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Group ◽  
Acute Pulmonary Embolism ◽  
Case Control Study ◽  
Chronic Thromboembolic Pulmonary Hypertension ◽  
Case Control ◽  
Thrombosis Risk ◽  
Thromboembolic Pulmonary Hypertension ◽  
Acute Pe ◽  
Control Study

Chronic thromboembolic pulmonary hypertension (CTEPH) is a serious complication of acute pulmonary embolism (PE) which remains underdiagnosed. A better understanding of risk factors for CTEPH would improve our ability to predict which PE survivors are at risk. Several medical conditions—including malignancy, splenectomy, thyroid hormone supplementation, the presence of an intravascular device, inflammatory bowel disease, osteomyelitis, and non-O blood group—have been associated with increased risk of CTEPH, primarily in studies comparing patients with CTEPH to individuals with non-thrombotic conditions. Because many of these conditions increase thrombosis risk, it remains unclear whether their association with CTEPH reflects a general effect on thrombosis risk, or a specific effect on the risk of developing CTEPH as an outcome of thrombosis. We performed a case-control study comparing the frequencies of these conditions in patients with CTEPH versus patients with acute PE who did not develop CTEPH. The conditions studied were equally frequent in the CTEPH and PE cohorts, although there was a trend towards an increased frequency of splenectomy and non-O blood group among the CTEPH cohort. Thus, other than the possible exceptions of splenectomy and non-O blood group, the investigated medical conditions do not appear likely to increase the risk of CTEPH as an outcome of acute PE, and thus are unlikely to be useful in predicting CTEPH risk among PE survivors.

scholarly journals Abo Blood Group, Atherothrombotic Comorbidities, and COVID-19: A Case-Control Study of their Association in the Mexican Population

2021 ◽  
Author(s):  
Jacqueline Gamboa-Aguilar ◽  
Ángela Carele Zamorano-Montaño ◽  
Aldo Enríquez-Osorio ◽  
Wendoline Torres-Cubillas ◽  
José Luis López-Arroyo ◽  
...  
Keyword(s):  
Blood Group ◽  
Case Control Study ◽  
Case Control ◽  
Mexican Population ◽  
Abo Blood Group ◽  
Control Study

ABO blood group system and risk of brain tumors: A retrospective case–control study in Northeast of China

2018 ◽  
Vol 3 (3) ◽  
pp. 49
Author(s):  
Chuanlu Jiang ◽  
Liang Chang ◽  
Shihong Zhao ◽  
Zhou Dan ◽  
Guofu Li ◽  
...  
Keyword(s):  
Brain Tumors ◽  
Blood Group ◽  
Case Control Study ◽  
Case Control ◽  
Abo Blood Group ◽  
Blood Group System ◽  
Retrospective Case ◽  
Group System ◽  
Northeast Of China ◽  
Control Study

scholarly journals Coronary Heart Disease and ABO Blood Group in Diabetic Women: A Case-Control Study

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Seyyed Hasan langari ◽  
Adele Bahar ◽  
Leila Asadian ◽  
Saeid Abediankenai ◽  
Seyed Shojaeddin Namazi ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Blood Group ◽  
Case Control Study ◽  
Case Control ◽  
Abo Blood Group ◽  
Control Study

scholarly journals Association between ABO blood group and primary knee osteoarthritis: a case-control study

2016 ◽  
Vol 7 ◽  
pp. 93
Author(s):  
Yue Ding ◽  
Changchuan Li ◽  
Chi Zhang ◽  
Guangtao Fu ◽  
Shixun Li ◽  
...  
Keyword(s):  
Knee Osteoarthritis ◽  
Blood Group ◽  
Case Control Study ◽  
Case Control ◽  
Abo Blood Group ◽  
Control Study

ABO blood group and esophageal carcinoma risk: from a case–control study in Chinese population to meta-analysis

2014 ◽  
Vol 25 (10) ◽  
pp. 1369-1377 ◽  
Author(s):  
Wei Wang ◽  
Lei Liu ◽  
Zhiwei Wang ◽  
Xiaopeng Lu ◽  
Min Wei ◽  
...  
Keyword(s):  
Esophageal Carcinoma ◽  
Blood Group ◽  
Chinese Population ◽  
Case Control Study ◽  
Meta Analysis ◽  
Case Control ◽  
Abo Blood Group ◽  
Carcinoma Risk ◽  
Control Study

scholarly journals Association of ABO blood group with severe falciparum malaria in adults: case control study and meta-analysis

2011 ◽  
Vol 10 (1) ◽  
pp. 309 ◽  
Author(s):  
Aditya K Panda ◽  
Santosh K Panda ◽  
Aditya N Sahu ◽  
Rina Tripathy ◽  
Balachandran Ravindran ◽  
...  
Keyword(s):  
Falciparum Malaria ◽  
Blood Group ◽  
Case Control Study ◽  
Meta Analysis ◽  
Case Control ◽  
Abo Blood Group ◽  
Severe Falciparum Malaria ◽  
Control Study
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