scholarly journals Circulation of influenza A viruses in dromedary camels in Saudi Arabia

2019 ◽  
Vol 12 (1) ◽  
pp. 143
Author(s):  
A. Al-Ghamdi ◽  
S. Al-amri ◽  
A. Tolah ◽  
E. Azhar ◽  
A. Hashem
Keyword(s):  
Saudi Arabia ◽  
Influenza A ◽  
Influenza A Viruses ◽  
Dromedary Camels

scholarly journals Molecular Evidence of Influenza A Virus Circulation in African Dromedary Camels Imported to Saudi Arabia, 2017–2018

2019 ◽  
Vol 6 (10) ◽  
Author(s):  
Abdulaziz Alghamdi ◽  
Ahmed M Hassan ◽  
Ahmed M Tolah ◽  
Sawsan S Alamari ◽  
Abdulrahman A Alzahrani ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Influenza A ◽  
Swine Influenza ◽  
Interspecies Transmission ◽  
Molecular Evidence ◽  
Influenza A Viruses ◽  
Influenza A H1n1 ◽  
Nasal Swabs ◽  
Close Relationship ◽  
Partial Genome

Abstract Little is known about influenza A viruses in dromedaries. Here, we detected influenza A viral RNA in 11 specimens (1.7 %) out of 665 nasal swabs collected from dromedaries between 2017 and 2018 in Saudi Arabia. Positive samples were detected only in imported camels from Sudan and Djibouti but not local ones. Partial genome sequencing indicates a close relationship to 2009–2019 human/swine influenza A H1N1 isolates from different countries, suggesting possible interspecies transmission. Taken together, dromedaries could represent a potentially unrecognized permissive host for these viruses, highlighting the need for enhanced surveillance in animals to aid implementation of one-health strategies.

scholarly journals Co-circulation of two sublineages of HPAI H5N1 virus in the Kingdom of Saudi Arabia with unique molecular signatures suggesting separate introductions into the commercial poultry and falconry sectors

2008 ◽  
Vol 89 (11) ◽  
pp. 2691-2697 ◽  
Author(s):  
Isabella Monne ◽  
Alice Fusaro ◽  
Mohamed Hamad Al-Blowi ◽  
Mahmoud Moussa Ismail ◽  
Owais Ahmed Khan ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Influenza A ◽  
Close Contact ◽  
Phylogenetic Analyses ◽  
Influenza A Viruses ◽  
Kingdom Of Saudi Arabia ◽  
Hpai H5n1 ◽  
Commercial Poultry ◽  
Amino Acid Mutations ◽  
Genetic Signatures

Since early 2007, the Kingdom of Saudi Arabia (KSA) has experienced several highly pathogenic avian influenza (HPAI) H5N1 outbreaks in the falconry and poultry sectors. The public health threat associated with peculiar husbandry systems, requiring close contact between humans and birds of prey, highlights the need of an improved understanding of the epidemiology and of the viral characteristics of H5N1 viruses circulating in the region. Here we report molecular and phylogenetic analyses of H5N1 viruses isolated in the KSA in 2007 in distinct compartments of avian husbandry. From the results of our investigation it appears that two separate introductions into the different sectors occurred. The identification of specific amino acid mutations, which are described as genetic signatures of human influenza A viruses or known to confer resistance to antiviral drugs, raises concerns for the possible human health implications of the KSA H5N1 viruses.

TMPRSS2 is essential for pathogenicity of H7N9 and H1N1 influenza A viruses in mice

Pneumologie ◽  
2014 ◽  
Vol 68 (02) ◽  
Author(s):  
C Tarnow ◽  
G Engels ◽  
A Arendt ◽  
F Schwalm ◽  
H Sediri ◽  
...  
Keyword(s):  
Influenza A ◽  
H1n1 Influenza ◽  
Influenza A Viruses

Killing two birds with one stone – Prenylated flavonoids disrupt the lethal synergism of influenza A viruses and pneumococci

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
U Grienke ◽  
M Richter ◽  
E Walther ◽  
A Hoffmann ◽  
J Kirchmair ◽  
...  
Keyword(s):  
Influenza A ◽  
Influenza A Viruses ◽  
Prenylated Flavonoids

Occurrence of temperature-sensitive influenza A viruses in nature.

1982 ◽  
Vol 41 (2) ◽  
pp. 353-359 ◽  
Author(s):  
C M Chu ◽  
S F Tian ◽  
G F Ren ◽  
Y M Zhang ◽  
L X Zhang ◽  
...  
Keyword(s):  
Influenza A ◽  
Temperature Sensitive ◽  
Influenza A Viruses

Heterogeneity of the mutation rates of influenza A viruses: isolation of mutator mutants.

1992 ◽  
Vol 66 (4) ◽  
pp. 2491-2494 ◽  
Author(s):  
P Suárez ◽  
J Valcárcel ◽  
J Ortín
Keyword(s):  
Influenza A ◽  
Mutation Rates ◽  
Influenza A Viruses
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