scholarly journals Characterization of a Group B Streptococcus infection based on the demographics, serotypes, antimicrobial susceptibility and genotypes of selected isolates from sterile and non-sterile isolation sites in three major hospitals in Malaysia

2017 ◽  
Vol 10 (1) ◽  
pp. 14-21 ◽  
Author(s):  
Mohd E.S. Suhaimi ◽  
Mohd N.M. Desa ◽  
Narges Eskandarian ◽  
Stella G. Pillay ◽  
Zalina Ismail ◽  
...  
Keyword(s):  
Antimicrobial Susceptibility ◽  
Group B Streptococcus ◽  
Group B

scholarly journals Characterization of Group B Streptococcus Isolated from Women in Saitama City, Japan

2012 ◽  
Vol 65 (6) ◽  
pp. 516-521 ◽  
Author(s):  
Hiroyuki Ueno ◽  
Yoshihiko Yamamoto ◽  
Akiko Yamamichi ◽  
Koji Kikuchi ◽  
Sumie Kobori ◽  
...  
Keyword(s):  
Group B Streptococcus ◽  
Group B

scholarly journals Group B Streptococcus Recto-Vaginal Colonization in Near-Term Pregnant Women, Southwest Ethiopia

2020 ◽  
Vol 30 (5) ◽  
Author(s):  
Woubishet Girma ◽  
Nadia Yimer ◽  
Tesfaye Kassa ◽  
Elias Yesuf
Keyword(s):  
Pregnant Women ◽  
Antimicrobial Susceptibility ◽  
Susceptibility Testing ◽  
Group B Streptococcus ◽  
Susceptibility Pattern ◽  
Southwest Ethiopia ◽  
Vaginal Colonization ◽  
History Of ◽  
Near Term ◽  
Group B

BACKGROUND: Group B Streptococcus (GBS) is recognized as an important cause of maternal and neonatal morbidity and mortality. Maternal vaginal carriage of GBS (Streptococcus agalactiae) can lead to vertical transmission to the neonate at the time of delivery. However, little is known about its prevalence, predictors and antibiotic susceptibility pattern in Jimma, Ethiopia. This study assessed the prevalence, antimicrobial susceptibility pattern and determinants of GBS recto-vaginal colonization among near-term pregnant women.METHODS: A cross-sectional study was conducted from May to August 2015 at Jimma University Medical Centre in Southwest Ethiopia. Data through questionnaire and GBS isolates from vaginal and rectal swabs were collected. Antimicrobial susceptibility testing was performed.RESULTS: The overall prevalence of GBS colonization among near term pregnant women (35-37 weeks) was 16.3% (22/135). The majority of GBS isolates were sensitive to Ampicillin and Penicillin G with 95.5% and 90.1%, respectively. Erythromycin and clindamycin were resisted by 50% and 40.9% of the isolates, respectively, whereas gentamicin was resisted by all isolates. GBS colonization was significantly associated with a history of preterm delivery (PTD) (AOR: 6.3, 95% CI: 1.42, 28.3) and history of urinary tract infection (UTI) during current pregnancy (AOR: 6.4, 95% CI, 1.95, 21.1).CONCLUSION: Our study indicated that one among six near-term pregnant women had recto-vaginal GBS colonization. In places where universal screening is not feasible, selective screening for factors particularly history of PTD and UTI during current pregnancy may be a reasonable option. Antibiotic susceptibility testing should be performed while using Erythromycin, Clindamycin or Gentamicin. 

scholarly journals Immunochemical characterization of the "native" type III polysaccharide of group B Streptococcus.

1976 ◽  
Vol 143 (2) ◽  
pp. 258-270 ◽  
Author(s):  
C J Baker ◽  
D L Kasper ◽  
C E Davis
Keyword(s):  
Group B Streptococcus ◽  
Molecular Size ◽  
Antigenic Determinants ◽  
Capsular Type ◽  
Polysaccharide Antigen ◽  
Native Form ◽  
Intact Cells ◽  
Type Iii ◽  
Group B

The type III polysaccharide of -roup B Streptococcus has been isolated and purified by a method that employs washing of intact cells at neutral pH. That the polysaccharide prepared by this procedure is the "native" type III antigen is suggested by its molecular size in excess of 10(6) daltons, its degradation by acid and heat treatment to a fragment with immunologic characteristics of the classical HCl antigen, and its type-specific serologic activity. The type III polysaccharide in native form contains sialic acid, galactose, glucose, glucosamine, heptose, and mannose. It is acidic in nature, is resistant to neuramindiase degradation, contains no O-acetyl groups, and does not share antigenic determinants with capsular type K1 antigen of Escherichia coli or Group B polysaccharide antigen of Neiserria meningitidis.

Characterization of group B Streptococcus isolated from sterile and non-sterile specimens in China

2018 ◽  
Vol 92 (1) ◽  
pp. 56-61 ◽  
Author(s):  
Shuping Nie ◽  
Xuedong Lu ◽  
Zhengjiang Jin ◽  
Juyi Gao ◽  
Dongli Ma ◽  
...  
Keyword(s):  
Group B Streptococcus ◽  
Group B

Characterization of the group-specific polysaccharide of group B Streptococcus

1984 ◽  
Vol 235 (2) ◽  
pp. 385-392 ◽  
Author(s):  
David G. Pritchard ◽  
Barry M. Gray ◽  
Hugh C. Dillon
Keyword(s):  
Group B Streptococcus ◽  
Specific Polysaccharide ◽  
Group B

scholarly journals Molecular and phenotypic characterization of invasive group B streptococcus strains from infants in Norway 2006–2007

2009 ◽  
Vol 15 (12) ◽  
pp. 1182-1185 ◽  
Author(s):  
H. Bergseng ◽  
J.E. Afset ◽  
A. Radtke ◽  
K. Loeseth ◽  
R.V. Lyng ◽  
...  
Keyword(s):  
Group B Streptococcus ◽  
Phenotypic Characterization ◽  
Invasive Group ◽  
Group B

scholarly journals Molecular Characterization of Nontypeable Group B Streptococcus

2006 ◽  
Vol 44 (7) ◽  
pp. 2398-2403 ◽  
Author(s):  
S. V. Ramaswamy ◽  
P. Ferrieri ◽  
A. E. Flores ◽  
L. C. Paoletti
Keyword(s):  
Molecular Characterization ◽  
Group B Streptococcus ◽  
Group B

scholarly journals Role of PCR in Rapid Detection Group B Streptococcus in Pregnant Females in Al-Quwayiyah General Hospital, Riyadh, Saudi Arabia

2021 ◽  
pp. 45-52
Author(s):  
E. S. Khater ◽  
A. S. Abdel-Motaal
Keyword(s):  
Saudi Arabia ◽  
Pregnant Women ◽  
General Hospital ◽  
Antimicrobial Susceptibility ◽  
Gestational Age ◽  
Group B Streptococcus ◽  
Predictive Values ◽  
Pregnant Females ◽  
Group B

Background: Group B streptococcus is one of the most common causes of severe neonatal infections. Aim: To detect the prevalence of group B. Streptococcus and their antimicrobial susceptibility and to assess the role of PCR as a rapid method of its detection. Place and Duration of the Study: A cross sectional and prospective cohort study was carried out from September 2019 to February 2020 in Gynaecology and Obstetrics OPD and inpatient units in Al- Quwayiyah General hospital, Riyadh, Saudi Arabia Methodology: Paired rectal/vaginal specimens were collected from 540 pregnant females with gestational age 35 or more, Each swab was inoculated into selective medium, Todd Hewitt, One swab is streaked onto blood agar plates incubated in 5% CO2 for 24h at 36ºC. β-hemolytic colonies growth is identified by Gram’s stain, colony morphology and CAMP test. The confirmation and antimicrobial susceptibility were done by Vitek II machine, The second swab was used for PCR to identify atr gene. Results: Out of 540 pregnant women 87 (16.1%) were colonized with GBS isolates. The positive GBS women aged 25 (22-34) and negative GBS women aged 23 (24-35) with no statistical difference. Patients aged more than 35 years old has the higher rate of positive GBS, 46.2%. No significant association detected between GBS and gestational age at delivery, antenatal visits, BMI and gravidity. The GBS strains isolated from pregnant women was 100% susceptible to linezolid and vancomycin followed by ampicillin (93.1%) and tobramicin (83.9%) then gentamicin (81.6%) and levofloxacin(78.2%) and showed least antibiotic susceptibility to erythromycin (26.4%). The PCR was positive in 145 (26.9%). Using culture as gold method, PCR sensitivity was 100% (95% CI: 91.62-100), while specificity was 83.2% (95% CI: 82.61-91.02). Negative and positive predictive values were 100% and 61% respectively. Kappa between the two methods was 0.71, which indicate major agreement. Conclusion: The GBS prevalence among the pregnant females in Al Quwayiyah General Hospital was 16.1%. Detection of GBS using new PCR technique was found to have high sensitivity and faster results, allowing efficient management of GBS and reduction in newborn morbidity and mortality however the cost is high for some laboratories. Further studies should be assessed to be both low cost and accurate rapid screening.

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