Sequence-based identification and characterization of nosocomial influenza A(H1N1)pdm09 virus infections

2012 ◽  
Vol 82 (3) ◽  
pp. 187-193 ◽  
Author(s):  
M. Jonges ◽  
J. Rahamat-Langendoen ◽  
A. Meijer ◽  
H.G. Niesters ◽  
M. Koopmans
Keyword(s):  
Influenza A ◽  
Virus Infections ◽  
Pdm09 Virus ◽  
Influenza A H1n1 ◽  
Identification And Characterization

scholarly journals Surveillance for Oseltamivir-Resistant Influenza A(H1N1)pdm09 Virus Infections During 2015–2016, United States

2016 ◽  
Vol 3 (suppl_1) ◽  
Author(s):  
Sarah Spencer ◽  
Ha Nguyen ◽  
Anwar Abd Elal ◽  
Angela P. Campbell ◽  
Jennifer Laplante ◽  
...  
Keyword(s):  
United States ◽  
Influenza A ◽  
Virus Infections ◽  
Pdm09 Virus ◽  
Influenza A H1n1

scholarly journals Characterization of influenza A(H1N1)pdm09 viruses in Germany in season 2019-2020 – co-circulation of an antigenic drift variant

2021 ◽  
Author(s):  
Marianne Wedde ◽  
Djin-Ye Oh ◽  
Silke Buda ◽  
Andrea Thürmer ◽  
Sandra Kaiser ◽  
...  
Keyword(s):  
Influenza A ◽  
Influenza Season ◽  
Vaccine Virus ◽  
Influenza Viruses ◽  
Antigenic Drift ◽  
Neuraminidase Inhibitors ◽  
Pdm09 Virus ◽  
Time Period ◽  
Influenza A H1n1

Background Influenza A(H1N1)pdm09 virus entered the human population in 2009 and evolved within this population for more than ten years. Despite genetic evolution no remarkable changes in the antigenic reactive pattern of these viruses were observed so far. Methods Primary respiratory samples of the German influenza virological sentinel were investigated by qPCR. Influenza virus-positive samples were characterized genetically and antigenetically. Results In December 2019, a antigenic drift variant characterized by an N156K substitution in the hemagglutinin of influenza A(H1N1)pdm09 virus emerged in Germany, which exhibited a reactivity to ferret antiserum that was an average 6 log2 lower than the vaccine virus A/Brisbane/02/2018 and the other A(H1N1)pdm09 viruses circulating in the influenza season 2019-2020. These viruses accounted for 20% of all A(H1N1)pdm09 viruses characterized in the German influenza sentinel. Patients infected with these viruses had a shorter median time period of medical consultation after onset of symptoms and were more frequently treated with neuraminidase inhibitors in comparison to patients infected with other A(H1N1)pdm09 viruses. Conclusions This parallel circulation of two antigenic variants of A(H1N1)pdm09 viruses which differ remarkably in their antigenic reactive pattern contributes to a greater variability in circulating influenza viruses and challenges vaccination.

scholarly journals Molecular Characterization of the Predominant Influenza A(H1N1)pdm09 Virus in Mexico, December 2011–February 2012

PLoS ONE ◽  
2012 ◽  
Vol 7 (11) ◽  
pp. e50116 ◽  
Author(s):  
Daniela de la Rosa-Zamboni ◽  
Joel A. Vázquez-Pérez ◽  
Santiago Ávila-Ríos ◽  
Ana Paola Carranco-Arenas ◽  
Christopher E. Ormsby ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Influenza A ◽  
Pdm09 Virus ◽  
Influenza A H1n1

scholarly journals Serum anti-neuraminidase antibody responses in human influenza A(H1N1)pdm09 virus infections

2019 ◽  
Vol 8 (1) ◽  
pp. 404-412 ◽  
Author(s):  
Herath M. T. K. Karunarathna ◽  
Ranawaka A. P. M. Perera ◽  
Vicky J. Fang ◽  
Hui-ling Yen ◽  
Benjamin John Cowling ◽  
...  
Keyword(s):  
Influenza A ◽  
Antibody Responses ◽  
Virus Infections ◽  
Human Influenza ◽  
Pdm09 Virus ◽  
Influenza A H1n1

Mixed polysaccharides derived from shiitake mushroom, Poriacocos, Ginger and Tangerine peel prevent the H1N1 virus infections in mice

2021 ◽  
Author(s):  
Diqi Yang ◽  
Minghua Hu ◽  
Hongmei Zhu ◽  
Jianguo Chen ◽  
Dehai Wang ◽  
...  
Keyword(s):  
Influenza A ◽  
Clinical Symptoms ◽  
H1n1 Virus ◽  
Global Public Health ◽  
Virus Infections ◽  
Shiitake Mushroom ◽  
Virus Challenge ◽  
Influenza A H1n1 ◽  
Public Health Challenges ◽  
Cellular Immune

Abstract The pandemic influenza A (H1N1) virus spread globally and posed one of the most serious global public health challenges. The traditional Chinese medicine is served as a complementary treatment strategy with vaccine immunization. Here, we demonstrated the mixed polysaccharides (MPs) derived from shiitake mushroom, poriacocos, ginger and tyangerine peel prevent the H1N1 virus infections in mice. MPs pretreatment attenuated H1N1 virus-induced weight loss, clinical symptoms and death. The lymphocytes detection results showed the CD3+, CD19+ and CD25+ cell proportions were up-regulated in thymus under MPs pretreatment. Besides, MPs pretreatment reduced the inflammatory cell infiltration and increased the cell proportions of CD19+, CD25+ and CD278+ in lung. However, MPs treatment have no effective therapeutic effect after H1N1 virus challenge. The current study suggested that pretreatment with MPs could attenuate H1N1 virus-induced lung injury and up-regulate humoral and cellular immune responses in non- immunized mice.

scholarly journals Seroepidemiology of pandemic influenza A (H1N1) 2009 virus infections in Pune, India

2010 ◽  
Vol 10 (1) ◽  
Author(s):  
Babasaheb V Tandale ◽  
Shailesh D Pawar ◽  
Yogesh K Gurav ◽  
Mandeep S Chadha ◽  
Santosh S Koratkar ◽  
...  
Keyword(s):  
Pandemic Influenza ◽  
Influenza A ◽  
Virus Infections ◽  
Influenza A H1n1

scholarly journals Seroprevalence study of infection with influenza A(H1N1)pdm09 virus in San Felipe Town, Chile

2013 ◽  
Vol 03 (07) ◽  
pp. 476-482
Author(s):  
Olea Andrea ◽  
Fasce Rodrigo ◽  
Aguilera Ximena ◽  
Oliva Otavio ◽  
Muñoz Sergio ◽  
...  
Keyword(s):  
Influenza A ◽  
Seroprevalence Study ◽  
Pdm09 Virus ◽  
Influenza A H1n1

scholarly journals New influenza A(H1N1) virus infections in France, April – May 2009

2009 ◽  
Vol 14 (21) ◽  
Author(s):  
Collective New influenza A(H1N1) investigation teams*
Keyword(s):  
North America ◽  
Active Surveillance ◽  
Influenza A ◽  
Clinical Characteristics ◽  
H1n1 Virus ◽  
Virus Infections ◽  
Influenza A H1n1 ◽  
Set Up

Since the emergence of a new influenza A(H1N1) virus in North America and its international spread, an active surveillance of cases of infection due to this virus has been set up in France in order to undertake appropriate measures to slow down the spread of the new virus. This report describes the epidemiological and clinical characteristics of the 16 laboratory confirmed cases diagnosed in France as of 20 May 2009.

scholarly journals Fluctuations in influenza-like illness epidemics and suicide mortality: A time-series regression of 13-year mortality data in South Korea

PLoS ONE ◽  
2021 ◽  
Vol 16 (2) ◽  
pp. e0244596
Author(s):  
Sun Jae Jung ◽  
Sung-Shil Lim ◽  
Jin-Ha Yoon
Keyword(s):  
Time Series ◽  
South Korea ◽  
Influenza A ◽  
Suicide Mortality ◽  
Mortality Data ◽  
Time Series Regression ◽  
Influenza Like Illness ◽  
Pdm09 Virus ◽  
Influenza A H1n1 ◽  
Novel Influenza A

Aims We explored the association between influenza epidemic and suicide mortality rates in a large population using a time-series regression of 13-year mortality data in South Korea. Methods Weekly suicide mortalities and influenza-like illness (ILI) were analyzed using time series regression. Regression coefficient for suicide mortality based on percentage change of ILI was calculated using a quasi-Poisson regression. Non-linear distributed lag models with quadratic function up to 24 weeks were constructed. Results The association between ILI and suicide mortality increased significantly up to 8 weeks post-influenza diagnosis. A significant positive association between ILI and suicide mortality was observed from 2009, when a novel influenza A(H1N1)pdm09 virus provoked a worldwide pandemic. No meaningful association between these factors was observed before 2009. Conclusion There was a significant positive relationship between ILI and suicide mortality after 2009, when a novel influenza A(H1N1)pdm09 virus provoked a worldwide pandemic.

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