scholarly journals Numerical and experimental study of expiratory flow in the case of major upper airway obstructions with fluid–structure interaction

2008 ◽  
Vol 24 (2) ◽  
pp. 250-269 ◽  
Author(s):  
F. Chouly ◽  
A. Van Hirtum ◽  
P.-Y. Lagrée ◽  
X. Pelorson ◽  
Y. Payan
Keyword(s):  
Experimental Study ◽  
Fluid Structure Interaction ◽  
Upper Airway ◽  
Fluid Structure ◽  
Structure Interaction ◽  
Airway Obstructions ◽  
Expiratory Flow

Using Two-Way Fluid-Structure Interaction to Study the Collapse of the Upper Airway of OSA Patients

2014 ◽  
Vol 553 ◽  
pp. 275-280 ◽  
Author(s):  
Mo Yin Zhao ◽  
Tracie J. Barber ◽  
Peter A. Cistulli ◽  
Kate Sutherland ◽  
Gary Rosengarten
Keyword(s):  
Computational Models ◽  
Treatment Success ◽  
Fluid Structure Interaction ◽  
Maximum Velocity ◽  
Upper Airway ◽  
Post Treatment ◽  
Mandibular Advancement ◽  
Fluid Structure ◽  
Structure Interaction ◽  
Obstructive Sleep

Obstructive Sleep Apnea (OSA) is a common sleep disorder characterized by repetitive collapse of the upper airway (UA) during sleep. Treatment options for OSA include mandibular advancement splints (MAS), worn intra-orally to protrude the lower jaw to stabilize the airway. However not all patients will respond to MAS therapy and individual effects on the upper airway are not well understood. Simulations of airway behavior represent a non-invasive means to understand this disorder and treatment responses in individual patients. The aims of this study was to perform analysis of upper airway (UA) occlusion and flow dynamics in OSA using the fluid structure interaction (FSI) method, and secondly to observe changes associated with MAS usage. Magnetic resonance imaging (MRI) scans were obtained with and without mandibular advance splint (MAS) treatment in a patient known to be a treatment responder. Computational models of the anatomically correct UA geometry were reconstructed for both pre-and post-treatment (MAS) conditions. By comparing the simulation results, the treatment success of MAS was demonstrated by smaller UA structure deformation (maximum 2mm) post-treatment relative to the pre-treatment fully collapsed (maximum 6mm) counterpart. The UA collapse was located at the oropharynx and the low oropharyngeal pressure (-51 Pa to-39 Pa) was induced by the velopharyngeal jet flow (maximum 10 m/s). The results support previous OSA computational fluid dynamics (CFD) studies by indicating similar UA pressure drop and maximum velocity values. These findings lay a firm platform for the application of computational models for the study of the biomechanical properties of the upper airway in the pathogenesis and treatment of OSA.

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