Dietary natural products and lung cancer: Effects and mechanisms of action

2019 ◽  
Vol 52 ◽  
pp. 316-331 ◽  
Author(s):  
Shi-Yu Cao ◽  
Ya Li ◽  
Xiao Meng ◽  
Cai-Ning Zhao ◽  
Sha Li ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Natural Products ◽  
Mechanisms Of Action

Actin-targeting natural products: structures, properties and mechanisms of action

2006 ◽  
Vol 63 (18) ◽  
pp. 2119-2134 ◽  
Author(s):  
J. S. Allingham ◽  
V. A. Klenchin ◽  
I. Rayment
Keyword(s):  
Natural Products ◽  
Mechanisms Of Action

Natural products: Potential targets of TME related long non-coding RNAs in lung cancer

Phytomedicine ◽  
2021 ◽  
Vol 93 ◽  
pp. 153782
Author(s):  
Rama Rao Malla ◽  
Vasudevaraju Padmaraju ◽  
Rakshmitha Marni ◽  
Mohammad Amjad Kamal
Keyword(s):  
Lung Cancer ◽  
Natural Products ◽  
Non Coding Rnas

Natural products show diverse mechanisms of action against Clostridium difficile

2018 ◽  
Vol 126 (2) ◽  
pp. 468-479 ◽  
Author(s):  
N. Roshan ◽  
T.V. Riley ◽  
D.R. Knight ◽  
J.H. Steer ◽  
K.A. Hammer
Keyword(s):  
Natural Products ◽  
Clostridium Difficile ◽  
Mechanisms Of Action

scholarly journals Natural products with therapeutic potential in melanoma metastasis

2015 ◽  
Vol 32 (8) ◽  
pp. 1170-1182 ◽  
Author(s):  
A. AlQathama ◽  
J. M. Prieto
Keyword(s):  
Natural Products ◽  
Cancer Treatment ◽  
Therapeutic Potential ◽  
Melanoma Cells ◽  
Mechanisms Of Action ◽  
Melanoma Metastasis ◽  
Pharmacological Effects ◽  
Cytotoxic Compounds

Natural products continue to provide lead cytotoxic compounds for cancer treatment but less attention has been given to antimigratory compounds. We here systematically and critically survey more than 30 natural products with direct in vitro and in vivo pharmacological effects on migration and/or metastasis of melanoma cells and chart the mechanisms of action for this underexploited property.

Anti-Malarial Drug Resistance

2022 ◽  
pp. 233-250
Author(s):  
Manish Kumar Dwivedi ◽  
Prashant Kumar Singh
Keyword(s):  
Natural Products ◽  
Protozoan Parasite ◽  
Mechanisms Of Action ◽  
New Drugs ◽  
Efficacy And Safety ◽  
Infected Female ◽  
Traditional Medicines ◽  
Anopheles Mosquitoes ◽  
Synthetic Drugs ◽  
Life Threatening

Malaria is a life-threatening infectious disease caused by a protozoan parasite of the genus Plasmodium. It is transmitted through the bites of infected female Anopheles mosquitoes. The global burden is estimated to be around 219 million cases in 87 countries. Natural compounds have been used primarily in the traditional medicine for thousands of years. For the treatment of malaria, natural products were used until the development of synthetic drugs, and most of the currently available anti-malarial drugs have been derived based on the compounds from these traditional medicinal plants. The current chapter tries to briefly indicate the emerging resistance against anti-malarial drugs and to discuss the recent research on natural products that have been evaluated for anti-malarial activity. Rigorous evaluation of the efficacy and safety of traditional medicines is required along with identification of active constituents in order to develop new drugs with novel mechanisms of action.

scholarly journals Plant Natural Products for the Control of Aedes aegypti: The Main Vector of Important Arboviruses

Molecules ◽  
2020 ◽  
Vol 25 (15) ◽  
pp. 3484 ◽  
Author(s):  
Maíra Rosato Silveiral Silvério ◽  
Laila Salmen Espindola ◽  
Norberto Peporine Lopes ◽  
Paulo Cézar Vieira
Keyword(s):  
Natural Products ◽  
Secondary Metabolites ◽  
Aedes Aegypti ◽  
Vector Control ◽  
Chemical Constituents ◽  
Mosquito Species ◽  
Mechanisms Of Action ◽  
Control Applications ◽  
Lower Toxicity ◽  
Plant Natural Products

The mosquito species Aedes aegypti is one of the main vectors of arboviruses, including dengue, Zika and chikungunya. Considering the deficiency or absence of vaccines to prevent these diseases, vector control remains an important strategy. The use of plant natural product-based insecticides constitutes an alternative to chemical insecticides as they are degraded more easily and are less harmful to the environment, not to mention their lower toxicity to non-target insects. This review details plant species and their secondary metabolites that have demonstrated insecticidal properties (ovicidal, larvicidal, pupicidal, adulticidal, repellent and ovipositional effects) against the mosquito, together with their mechanisms of action. In particular, essential oils and some of their chemical constituents such as terpenoids and phenylpropanoids offer distinct advantages. Thiophenes, amides and alkaloids also possess high larvicidal and adulticidal activities, adding to the wealth of plant natural products with potential in vector control applications.

scholarly journals A cocktail of betulinic acid, parthenolide, honokiol and ginsenoside Rh2 in liposome systems for lung cancer treatment

Nanomedicine ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. 41-54 ◽  
Author(s):  
Xin Jin ◽  
Qing Yang ◽  
Ning Cai ◽  
Zhenhai Zhang
Keyword(s):  
Lung Cancer ◽  
Natural Products ◽  
Betulinic Acid ◽  
Synergistic Action ◽  
Ginsenoside Rh2 ◽  
High Incidence ◽  
High Incidence Rate ◽  
Very High

Aim: Lung cancer has a very high incidence rate, and thus, there is an urgent need for novel and effective therapies. Materials & methods: In this study, we proposed a potential treatment option by combining four natural products in liposome systems. Results: In vitro studies indicated that the combination of betulinic acid, parthenolide, honokiol and ginsenoside Rh2 exhibited a synergistic action. When these four natural products were loaded into liposome systems, we observed an increased effect. The relative action was also observed in vivo. The cisplatin group presented obvious kidney damage, whereas both cocktail therapy and cocktail liposome therapy were safer. Conclusion: Therefore, we propose cocktail liposome systems may provide a more efficient and safer treatment for lung cancer.

Characterization of apoptosis induced by marine natural products in non small cell lung cancer A549 cells

2006 ◽  
Vol 63 (19-20) ◽  
pp. 2377-2386 ◽  
Author(s):  
A. Catassi ◽  
A. Cesario ◽  
D. Arzani ◽  
P. Menichini ◽  
A. Alama ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Natural Products ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Marine Natural Products ◽  
A549 Cells ◽  
Small Cell ◽  
Small Cell Lung
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