Anti-proliferative, anti-inflammatory and anti-mutagenic activities of a Prunus mahaleb L. anthocyanin-rich fruit extract

2016 ◽  
Vol 27 ◽  
pp. 537-548 ◽  
Author(s):  
Carmela Gerardi ◽  
Stefania Frassinetti ◽  
Leonardo Caltavuturo ◽  
Antonella Leone ◽  
Raffaella Lecci ◽  
...  
Keyword(s):  
Fruit Extract ◽  
Prunus Mahaleb ◽  
Anti Inflammatory

scholarly journals Mechanisms of Analgesic and Anti-Inflammatory Properties of Annona muricata Linn. (Annonaceae) Fruit Extract in Rodents

2014 ◽  
Vol 17 (12) ◽  
pp. 1375-1382 ◽  
Author(s):  
Ismail O. Ishola ◽  
Olufunsho Awodele ◽  
Abayomi Micheal Olusayero ◽  
Charles O. Ochieng
Keyword(s):  
Annona Muricata ◽  
Fruit Extract ◽  
Anti Inflammatory

Evaluation of Momordica charantia L. Fruit Extract for Analgesic and Anti-inflammatory activities using in vivo Assay

2012 ◽  
Vol 6 (3) ◽  
pp. 236-244 ◽  
Author(s):  
M. Ullah ◽  
Mir Showkat ◽  
Nazim Uddin Ahme ◽  
Saiful Islam ◽  
Nurul Absar
Keyword(s):  
Momordica Charantia ◽  
Fruit Extract ◽  
In Vivo Assay ◽  
Anti Inflammatory

scholarly journals ASSESSMENT OF ANTI-INFLAMMATORY ACTIVITY OF ETHANOLIC EXTRACT OF ASAM KANDIS (GARCINIA XANTHOCHYMUS HOOK. F. EX T. ANDERSON) FRUIT

2018 ◽  
Vol 11 (4) ◽  
pp. 81
Author(s):  
Hanafis Sastra Winata ◽  
Rosidah Rosidah ◽  
Panal Sitorus
Keyword(s):  
Ethanolic Extract ◽  
Negative Control Group ◽  
Positive Control ◽  
Negative Control ◽  
Inflammatory Activity ◽  
Control Group ◽  
Phytochemical Screening ◽  
Fruit Extract ◽  
Garcinia Xanthochymus ◽  
Anti Inflammatory

 Objective: The objective of this study was to evaluate the anti-inflammatory activity in acute and subacute models of inflammation from ethanolic fruit extract of Asam kandis (Garcinia xanthochymus Hook. f. ex T. Anderson) in animal (rats) models.Methods: Pleliminary phytochemical screening was carried out by using standard procedures.. Assessment of acute and subacute models of inflammation was using carrageenan-induced paw edema method and cotton pellet granuloma method using three dosage treatments; 200 mg/kg BW, 400 mg/kg BW, and 800 mg/kg BW along with a negative control group (0.5% Na CMC) and positive control (Na diclofenac 2.25 mg/kg BW). The inhibition period was observed at 30, 60, 90, 120, 150, and 180 min time intervals.Result: The phytochemical screening showed that the ethanolic fruit extract from Asam kandis contain contains flavonoids, glycosides, steroids, and triterpenoids. The anti-inflammatory result showed that the strongest inhibition produced by ethanolic fruit extract of Asam kandis occurred on the dosage of 800 mg/kg BW compared to the other doses (200 and 400 mg/kg BW) throughout the observation period.Conclusion: This finding indicated that ethanolic fruit extract of Asam kandis (G. xanthochymus Hook. f. ex T. Anderson) might become an interesting candidate for treatment of inflammation.

Prunus Mahaleb Fruit Extract Prevents Chemically Induced Colitis and Enhances Mitochondrial Oxidative Metabolism via the Activation of the Nrf2 Pathway

2019 ◽  
Vol 63 (22) ◽  
pp. 1900350
Author(s):  
Alessandra Ferramosca ◽  
Lucia Treppiccione ◽  
Mariangela Di Giacomo ◽  
Vera Rotondi Aufiero ◽  
Giuseppe Mazzarella ◽  
...  
Keyword(s):  
Oxidative Metabolism ◽  
Fruit Extract ◽  
Nrf2 Pathway ◽  
Chemically Induced ◽  
Prunus Mahaleb ◽  
Mitochondrial Oxidative Metabolism

scholarly journals CACTUS PEAR FRUIT EXTRACT EXERTS ANTI-INFLAMMATORY EFFECTS IN CARRAGEENIN-INDUCED RAT PLEURISY

2015 ◽  
pp. 19-25
Author(s):  
M. Allegra ◽  
L. Tesoriere ◽  
M.A. Livrea ◽  
A. Ianaro ◽  
E. Panza
Keyword(s):  
Pear Fruit ◽  
Fruit Extract ◽  
Cactus Pear ◽  
Anti Inflammatory

scholarly journals The Effectiveness of the Antiinfamation Combination Gel of Okra Fruit (Abelmoschus esculentus) Extracts and Shallots Extract (Allium cepa L.)

2020 ◽  
Vol 5 (1) ◽  
Author(s):  
Sara Nurmala ◽  
Moerfia Moerfia ◽  
Santi Novianti
Keyword(s):  
Wound Healing ◽  
Allium Cepa ◽  
The United States ◽  
Abelmoschus Esculentus ◽  
Male Rats ◽  
Cell Multiplication ◽  
Fruit Extract ◽  
White Rats ◽  
Allium Cepa L ◽  
Anti Inflammatory

Wound is a condition that is the destruction of the unity or network components, which are specifically found the substance of tissue damaged or lost, either damage the continuity of the skin, mucous membranes and bones or other organs. Wound healing is a very complex process involving many cells. The process of wound healing is portrayed as occurs in biological surgical wound occurred. Several phases of wound healing are: the process of inflammation (inflammatory), the process of cell multiplication (proliferation) and cell maturation process (maturase). Okra is a plant that allegedly came from Southeast Asia. Okra has grown in many countries in almost all over the world. In the UK okra known as the Lady's Finger, in India it is called by the name of Bhindi while the United States called Gumbo. In Indonesia, this plant also has a local name that is Rabamea (Bima), Coffee Java (Java), Arabian Coffee (Sulawesi), Hoinu (Southeast Sulawesi), but better known by the name of okra. This study aims to determine the effective concentration and determine the length of time of wound healing using a combination gel okra fruit extract (Abelmoschus esculentus) And shallots (Allium cepa L.) as an anti-inflammatory against cuts in male white rats (Sprague -Dawley) with a length of observation for 9 days. This study uses Betadine® ointment as a positive control. The results showed the combination of fruit extract gel okra 6% and shallots 2% contained in the formula 3 most effective as an anti-inflammatory against cuts in male rats by administration for 6 days.

scholarly journals Phytochemical Composition, Anti-Inflammatory and ER Stress-Reducing Potential of Sambucus ebulus L. Fruit Extract

Plants ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 2446
Author(s):  
Oskan Tasinov ◽  
Ivayla Dincheva ◽  
Ilian Badjakov ◽  
Yoana Kiselova-Kaneva ◽  
Bistra Galunska ◽  
...  
Keyword(s):  
Amino Acids ◽  
Er Stress ◽  
Inflammatory Markers ◽  
Fruit Extract ◽  
Protein Levels ◽  
Phytochemical Composition ◽  
Pathological Conditions ◽  
Sambucus Ebulus ◽  
Anti Inflammatory ◽  
Reducing Potential

Sambucus ebulus L. (SE) fruits are used for their immunostimulation, hematopoietic and antiviral potential. Recently, we focused on analyzing the mechanism underlying SE fruit aqueous extract’s (FAE) immunomodulation and anti-inflammatory activities, with attention to its endoplasmic reticulum (ER) stress-reducing potential. J774A.1 macrophages were treated with SE FAE alone or in conditions of lipopolysaccharides (LPS) stimulation. Using GC–MS and LC–MS/MS, its phytochemical composition was analyzed. To measure transcription and protein levels, we used qPCR and Western blot, respectively. The prevailing phytochemicals in SE FAE were hydroxycinnamic acids, proanthocyanidins and anthocyanins. The content of some amino acids, organic acids, alcohols, fatty acids and esters were newly reported. Extracts exerted an immunostimulation potential by stimulating IL-6, TNFα, Ccl2, COX2 and iNOS transcription, without inducing ER stress. SE FAE suppressed the LPS-induced transcription of inflammation related genes (IL-1β, IL-6, TNFα, Ccl2, Icam-1, Fabp4, COX2, iNOS, Noxo1, IL-1ra, Sirt-1) and reduced the protein levels of iNOS, peIF2α, ATF6α and CHOP. The effects were comparable to that of salicylic acid. SE suppresses LPS-stimulated inflammatory markers on the transcription and translation levels. Targeting ER stress is possibly another mechanism underlying its anti-inflammatory potential. These findings reveal the potential of SE fruits as a beneficial therapeutic of inflammation and ER stress-related pathological conditions.

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