Anti-obesity and anti-inflammatory effects of high hydrostatic pressure extracts of ginseng in high-fat diet induced obese rats

2014 ◽  
Vol 10 ◽  
pp. 169-177 ◽  
Author(s):  
Sunyoon Jung ◽  
Mak-Soon Lee ◽  
Yoonjin Shin ◽  
Chong-Tai Kim ◽  
In-Hwan Kim ◽  
...  
Keyword(s):  
Hydrostatic Pressure ◽  
High Hydrostatic Pressure ◽  
High Fat Diet ◽  
High Fat ◽  
Obese Rats ◽  
Anti Inflammatory

scholarly journals Antidyslipidemic, Anti-Inflammatory, and Antioxidant Activities of Aqueous Leaf Extract of Dioscoreophyllum cumminsii (Stapf) Diels in High-Fat Diet-Fed Rats

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
O. B. Ibitoye ◽  
U. M. Ghali ◽  
J. B. Adekunle ◽  
J. N. Uwazie ◽  
T. O. Ajiboye
Keyword(s):  
Aqueous Extract ◽  
High Fat Diet ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Protein Carbonyl ◽  
Lipoprotein Cholesterol ◽  
Low Density Lipoprotein Cholesterol ◽  
High Fat ◽  
Obese Rats ◽  
Anti Inflammatory

Dioscoreophyllum cumminsii (Stapf) Diels leaves are widely used in the treatment of diabetes, obesity, and cardiovascular related complications in Nigeria. This study investigates the anti-inflammatory and antiobesity effect of aqueous extract of Dioscoreophyllum cumminsii leaves in high-fat diet- (HFD-) induced obese rats. HFD-fed rats were given 100, 200, and 400 mgkg−1 body weight of aqueous extract of Dioscoreophyllum cumminsii leaves for 4 weeks starting from 9th week of HFD treatment. D. cumminsii leaves aqueous extract reversed HFD-mediated decrease in the activities of superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, and glucose 6-phosphate dehydrogenase. Moreover, HFD-mediated elevation in the levels of conjugated dienes, lipid hydroperoxides, malondialdehyde, protein carbonyl, and DNA fragmentation in rats liver was lowered. HFD-mediated alterations in serum total cholesterol, triacylglycerol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and very low-density lipoprotein cholesterol were significantly reversed by the extract. The treatment of HFD-fed rats reduced the levels of insulin, leptin, protein carbonyl, fragmented DNA, and tumour necrosis factor-α and interleukin- (IL-) 6 and IL- 8 and increased the adiponectin level. This study showed that aqueous extract of Dioscoreophyllum cumminsii leaves has potential antiobesity and anti-inflammatory effects through modulation of obesity-induced inflammation, oxidative stress, and obesity-related disorder in HFD-induced obese rats.

scholarly journals Fruit vinegars attenuate cardiac injury via anti-inflammatory and anti-adiposity actions in high-fat diet-induced obese rats

2016 ◽  
Vol 55 (1) ◽  
pp. 43-52 ◽  
Author(s):  
Abdenour Bounihi ◽  
Arezki Bitam ◽  
Asma Bouazza ◽  
Lyece Yargui ◽  
Elhadj Ahmed Koceir
Keyword(s):  
High Fat Diet ◽  
Cardiac Injury ◽  
High Fat ◽  
Obese Rats ◽  
Anti Inflammatory

scholarly journals Anti‐adipogenic and anti‐inflammatory effects of high hydrostatic pressure extract of red ginseng in diet‐induced obese rats

2015 ◽  
Vol 29 (S1) ◽  
Author(s):  
Hyeyoung Park ◽  
Sunyoon Jung ◽  
Mak‐Soon Lee ◽  
Yoonjin Shin ◽  
Seunghae Kim ◽  
...  
Keyword(s):  
Hydrostatic Pressure ◽  
High Hydrostatic Pressure ◽  
Red Ginseng ◽  
Obese Rats ◽  
Anti Inflammatory

scholarly journals High Hydrostatic Pressure Extract of Red Ginseng Attenuates Inflammation in Rats with High-fat Diet Induced Obesity

2015 ◽  
Vol 20 (4) ◽  
pp. 253-259 ◽  
Author(s):  
Sunyoon Jung ◽  
Mak-Soon Lee ◽  
Yoonjin Shin ◽  
Chong-Tai Kim ◽  
In-Hwan Kim ◽  
...  
Keyword(s):  
Hydrostatic Pressure ◽  
High Hydrostatic Pressure ◽  
High Fat Diet ◽  
Red Ginseng ◽  
High Fat ◽  
Diet Induced Obesity

Antiobesity activity of fermentedAngelicae gigantisby high fat diet-induced obese rats

2011 ◽  
pp. 1-11 ◽  
Author(s):  
Jae-Young Cha ◽  
Jae-Jun Jeong ◽  
Chang-Su Park ◽  
Hee-Young Ahn ◽  
Hyung-In Moon ◽  
...  
Keyword(s):  
High Fat Diet ◽  
High Fat ◽  
Obese Rats
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