Antiosteoporotic activity of Er-Xian Decoction, a traditional Chinese herbal formula, in ovariectomized rats

2006 ◽  
Vol 108 (1) ◽  
pp. 96-102 ◽  
Author(s):  
Hua Nian ◽  
Lu-Ping Qin ◽  
Qiao-Yan Zhang ◽  
Han-Chen Zheng ◽  
Yuan Yu ◽  
...  
Keyword(s):  
Ovariectomized Rats ◽  
Herbal Formula ◽  
Chinese Herbal Formula ◽  
Chinese Herbal

scholarly journals Treatment with QiBaoMeiRan, a Kidney-Invigorating Chinese Herbal Formula, Antagonizes Estrogen Decline in Ovariectomized Rats

2014 ◽  
Vol 17 (4) ◽  
pp. 372-381 ◽  
Author(s):  
Ying Xu ◽  
Xiao-ping Ma ◽  
Jie Ding ◽  
Zhen-li Liu ◽  
Zhi-qian Song ◽  
...  
Keyword(s):  
Ovariectomized Rats ◽  
Herbal Formula ◽  
Chinese Herbal Formula ◽  
Chinese Herbal

scholarly journals In VivoStudy on the Pharmacological Interactions between a Chinese Herbal Formula ELP and Antiresorptive Drugs to Counteract Osteoporosis

2012 ◽  
Vol 2012 ◽  
pp. 1-11 ◽  
Author(s):  
Chun-Hay Ko ◽  
Wing-Sum Siu ◽  
Hing-Lok Wong ◽  
Si Gao ◽  
Wai-Ting Shum ◽  
...  
Keyword(s):  
Synergistic Effects ◽  
Ovariectomized Rats ◽  
Therapeutic Effects ◽  
Herbal Formula ◽  
Mineral Density ◽  
Chinese Herbal Formula ◽  
Chinese Herbal ◽  
Pharmacological Interactions ◽  
Long Term Treatment ◽  
Antiresorptive Drugs

Antiresorptive drugs, alendronate and raloxifene, are effective in lowering bone mineral density (BMD) loss in postmenopausal women. However, long-term treatment may be associated with serious side effects. Our research group has recently discovered that a Chinese herbal formula, ELP, could significantly reduce BMD loss in animal and human studies. Therefore, the present study aimed to investigate the potential synergistic bone-protective effects of different herb-drug combinations using ovariectomized rats. To assess the efficacy of different combinations, the total BMD was monitored biweekly in the 8-week course of daily oral treatment. Bone microarchitecture, bone strength, and deoxypyridinoline level were also determined after 8 weeks. From our results, coadministration of ELP and raloxifene increased the total tibial BMD by 5.26% (2.5 mg/kg/day of raloxifene;P=0.014) and 5.94% (0.25 mg/kg/day of raloxifene;P=0.026) when compared with the respective dosage groups with raloxifene alone. Similar synergistic effects were also observed in BMD increase at distal femur (0.25 mg/kg/day;P=0.001) and reduction in urinary deoxypyridinoline crosslink excretion (2.5 and 0.25 mg/kg/day; bothP=0.02). However, such interactions could not be observed in all alendronate-treated groups. Our data provide first evidence that ELP could synergistically enhance the therapeutic effects of raloxifene, so that the clinical dosage of raloxifene could be reduced.

Inhibitory effects of Chinese herbal formula Bingdeling on four common bacteria in vitro

2010 ◽  
Vol 30 (2) ◽  
pp. 212-214
Author(s):  
Hong QIAN ◽  
Nong XIAO ◽  
Zhi-feng QIN ◽  
Yan-jun LIU ◽  
Yi-jun SHEN ◽  
...  
Keyword(s):  
Herbal Formula ◽  
Inhibitory Effects ◽  
Chinese Herbal Formula ◽  
Chinese Herbal

scholarly journals Metabolomics study of the therapeutic mechanism of a Chinese herbal formula on collagen-induced arthritis mice

RSC Advances ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. 3716-3725 ◽  
Author(s):  
Zhen Jin ◽  
Ji-da Zhang ◽  
Xin Wu ◽  
Gang Cao
Keyword(s):  
Rheumatoid Arthritis ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Herbal Formula ◽  
Collagen Induced Arthritis ◽  
Chinese Herbal Formula ◽  
Chinese Herbal ◽  
Therapeutic Mechanism ◽  
Metabolomics Study

Wenjinghuoluo (WJHL) prescription, the typical rheumatoid arthritis (RA) treatment compound in traditional Chinese medicine, shows favorable efficacy.

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