Using Bioactive Glasses for the Treatment of Periodontal Intrabony Defects may Result in Modest Probing Depth Reduction and Clinical Attachment Level Gain Compared to Open Flap Debridement

2012 ◽  
Vol 12 (4) ◽  
pp. 209-211
Author(s):  
Hsun-Liang Chan ◽  
Hom-Lay Wang
Keyword(s):  
Intrabony Defects ◽  
Bioactive Glasses ◽  
Clinical Attachment Level ◽  
Probing Depth ◽  
Open Flap Debridement ◽  
Attachment Level ◽  
Depth Reduction

scholarly journals Evaluation of Bovine Derived Xenograft Combined with Bioresorbable Collagen Membrane in Treatment of Intrabony Defects

2020 ◽  
Vol 4 (2) ◽  
pp. 61-67
Author(s):  
Ranjita Shrestha Gorkhali ◽  
Shaili Pradhan ◽  
Rejina Shrestha ◽  
Shweta Agrawal ◽  
Krishna Lamicchane ◽  
...  
Keyword(s):  
Test Group ◽  
Control Group ◽  
Collagen Membrane ◽  
Intrabony Defects ◽  
Pocket Depth ◽  
Clinical Attachment Level ◽  
Probing Pocket Depth ◽  
Open Flap Debridement ◽  
Attachment Level ◽  
Depth Reduction

Introduction: Treatment of periodontal diseases done by surgical therapy depends upon extent and severity of disease. The ultimate goal of periodontal reconstructive surgery is to regenerate tissues destroyed during periodontal disease. Objective: To evaluate the effectiveness of bovine-derived xenograft with collagen membrane in treatment of intrabony defects by comparing it with open flap debridement alone. Methods: This non-randomised controlled trial was conducted after ethical clearance, at Bir hospital from 2018 March to 2019 April. The study recruited 38 patients by convenience sampling, age from 25-44 years, with chronic periodontitis, and willing to sign informed consent. Intrabony defects were treated by open flap debridement with bovine-derived xenograft and bioresorbable collagen membrane (Test group) and open flap debridement alone (Control group). Probing pocket depth, clinical attachment level, gingival recession, oral hygiene status, and gingival status were assessed at baseline and six months. Results: Six months after therapy, in Test group probing pocket depth reduction was 5.2 mm and gain in mean clinical attachment level was 4.3 mm. In Control group, mean probing pocket depth reduction was 3.8 mm and mean gain in clinical attachment level was 2.7 mm. The test treatment resulted in statistically higher probing pocket depth reduction and clinical attachment level gain than Control group. Conclusion: Both therapies resulted in significant probing pocket depth reductions and clinical attachment gains, and treatment with open flap debridement with bovine-derived xenografts and collagen membrane resulted in significantly higher probing pocket depth reduction and clinical attachment gain than treatment with open flap debridement alone.

scholarly journals Treatment of Intrabony Defects with a Combination of Hyaluronic Acid and Deproteinized Porcine Bone Mineral

Materials ◽  
2021 ◽  
Vol 14 (22) ◽  
pp. 6795
Author(s):  
Darko Božić ◽  
Ivan Ćatović ◽  
Ana Badovinac ◽  
Larisa Musić ◽  
Matej Par ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Bone Mineral ◽  
Gingival Recession ◽  
Intrabony Defects ◽  
Clinical Attachment Level ◽  
New Approach ◽  
Novel Approach ◽  
Probing Depth ◽  
Baseline Values ◽  
Attachment Level

Background: this study evaluates the clinical outcomes of a novel approach in treating deep intrabony defects utilizing papilla preservation techniques with a combination of hyaluronic acid (HA) and deproteinized porcine bone mineral. Methods: 23 patients with 27 intrabony defects were treated with a combination of HA and deproteinized porcine bone mineral. Clinical attachment level (CAL), pocket probing depth (PPD), gingival recession (REC) were recorded at baseline and 6 months after the surgery. Results: At 6 months, there was a significant CAL gain of 3.65 ± 1.67 mm (p < 0.001) with a PPD reduction of 4.54 ± 1.65 mm (p < 0.001), which was associated with an increase in gingival recession (0.89 ± 0.59 mm, p < 0.001). The percentage of pocket resolution based on a PPD ≤4 mm was 92.6% and the failure rate based on a PPD of 5 mm was 7.4%. Conclusions: the present findings indicate that applying a combined HA and xenograft approach in deep intrabony defects provides clinically relevant CAL gains and PPD reductions compared to baseline values and is a valid new approach in treating intrabony defects.

scholarly journals Surgical Treatment of Periodontal Intrabony Defects with Calcium Sulphate in Combination with Beta Tricalcium Phosphate – A 12-Month Retrospective Clinical Evaluation

2010 ◽  
Vol 53 (4) ◽  
pp. 229-234 ◽  
Author(s):  
Sujith Sukumar ◽  
Ivo Dřízhal ◽  
Josef Bukač ◽  
Vladimíra Paulusová ◽  
Shriharsha Pilathadka
Keyword(s):  
Tissue Regeneration ◽  
Tricalcium Phosphate ◽  
Gingival Recession ◽  
Calcium Sulphate ◽  
Intrabony Defects ◽  
Clinical Attachment Level ◽  
Beta Tricalcium Phosphate ◽  
Probing Depth ◽  
One Year ◽  
Attachment Level

Alloplastic bone graft materials are widely been used in combination with barrier membranes to achieve guided tissue regeneration in the treatment of periodontal intrabony defects. This study was designed to evaluate the clinical outcome of a composite material, beta tricalcium phosphate in combination with calcium sulphate in the treatment of periodontal intrabony defects. The combination of these materials is believed to aid in guided tissue regeneration owing to their properties. Thirty nine intrabony defects in 21 patients were treated with Fortoss® Vital (Biocomposites, Staffordshire, UK). Clinical parameters were evaluated including changes in probing depth, clinical attachment level/loss and gingival recession at baseline and one year postoperatively. The mean differences in measurements between the baseline and one year postoperatively are a reduction of 1.98±1.16 mm (p=0.000) in case of probing depth and a gain of 1.68±1.12 mm (p=0.000) in clinical attachment level and an increase of 0.31±0.67 mm (p=0.009) in gingival recession measurements. The study results show that the treatment with a combination of beta tricalcium phosphate and calcium sulphate led to a significantly favorable clinical improvement in periodontal intrabony defects one year postoperatively.

Effects of Mixture of Fibrin-Fibronectin Sealant System and Calcium Carbonate in Periodontal Intrabony Defects

2006 ◽  
Vol 309-311 ◽  
pp. 1397-1400
Author(s):  
Ui Won Jung ◽  
S.J. Chang ◽  
Seong Ho Choi ◽  
C.S. Kim ◽  
Jung Kiu Chai
Keyword(s):  
Calcium Carbonate ◽  
Gingival Recession ◽  
Control Group ◽  
Intrabony Defects ◽  
Clinical Attachment Level ◽  
Intrabony Defect ◽  
Probing Depth ◽  
Group 2 ◽  
Attachment Level ◽  
Experimental Group

This study evaluated the effects of mixture of fibrin-fibronectin sealant system(FFSS) and calcium carbonate(CC) in periodontal intrabony defects. Thirty six sites with two or three wall intrabony defect were used. 14 defects treated with periodontal flap surgery were assigned as the control group. 11 defects treated with CC implantation were designed as experimental group 1 and 11 defects, treated with CC and FFSS implantation as experimental group 2. The control and experimental groups all achieved statistically significant improvements in probing depth and clinical attachment level from the baseline (P<0.01). In mean postsurgery probing depth and gingival recession reduction, there were no statiscally significant differences between the experimental groups and the controls. However, mean postsurgery clinical attachment levels of both experimental groups improved significantly more than that of the controls. As a result, we suggest that mixture of FFSS and CC can be used effectively in intrabony defect as osteoconductive materials.

scholarly journals Evaluation of PRF Efficiency in the Treatment of Infrabony Defects

PRILOZI ◽  
2020 ◽  
Vol 41 (1) ◽  
pp. 79-86
Author(s):  
Jana Milutinovic ◽  
Mirjana Popovska ◽  
Biljana Rusevska ◽  
Milan Nacevski ◽  
Stefan Anastasovski ◽  
...  
Keyword(s):  
Test Group ◽  
Control Group ◽  
Clinical Parameters ◽  
Flap Surgery ◽  
Clinical Attachment Level ◽  
Positive Effects ◽  
Probing Depth ◽  
Infrabony Defects ◽  
Open Flap Debridement ◽  
Attachment Level

AbstractAim: The present study aimed to investigate the effectiveness of PRF in the treatment of infrabony defects in patients with chronic periodontitis by evaluating the clinical outcome through periodontal depth, clinical attachment level at the baseline, 6 and 9 months post operatively.Material and Methods: Sixty infrabony defects with probing depth ≥ 5 mm were treated. The inclusion criterion was the necessity for surgical bilateral maxillary treatment. By using split-mouth study design, each patient had one side treated with conventional flap surgery and the other side with conventional flap surgery and PRF. Clinical parameters, such as probing depth (PD) and clinical attachment lost (CAL), were recorded in both groups at baseline, 6 and 9 months post operatively.Results: Positive effects for all clinical and radiographic parameters were evident in the group with PRF. Mean PD reduction demonstrated statistically significant greater results in the test group (4.00±1.07 mm) compared to the control one (4.83±0.99 mm), p = 0.003 after 9 months postoperatively. After 9 months, there were better results in the test group compared to the control group for CAL (5.60±1.61 mm, 6.20±1.58 mm), but statistically not significant.Conclusion: Additional use of PRF in the conventional surgical treatment of infrabony defects demonstrated better parameters than the open flap debridement alone.

scholarly journals Application of Glass Reinforced Hydroxyapatite Composite in the Treatment of Human Intrabony Periodontal Angular Defects – Two Case Reports

2010 ◽  
Vol 161 ◽  
pp. 93-101 ◽  
Author(s):  
G. Pavan Kumar ◽  
A. Jaya Kumar ◽  
P. Krishnanjaneya Reddy ◽  
Sooraj Hussain Nandyala ◽  
M.A. Lopes ◽  
...  
Keyword(s):  
Case Reports ◽  
Clinical Parameters ◽  
Regenerative Therapy ◽  
Synthetic Graft ◽  
Bioactive Glasses ◽  
Clinical Attachment Level ◽  
Probing Depth ◽  
Hydroxyapatite Composite ◽  
Attachment Level ◽  
Implantation Period

Bony defects caused by periodontitis are often treated by regenerative therapy using autografts and/or allografts. Alloplasts such as hydroxyapatite or ceramics and bioactive glasses are used as osteoconductive materials that serve as scaffold for new bony ingrowth. The purpose of this study was to ascertain the possible regenerative capability of glass reinforced hydroxyapatite (Bonelike¬)¬¬¬ an osteoconductive synthetic graft in the treatment of human periodontal intrabony angular defects. The material was placed in 2 defects in 2 individual patients and clinical parameters such as probing depth (PD) and clinical attachment level (CAL) have been included. Bone fill was determined using an intra oral periapical radiograph (IOPA) and Autocad Software. After 3 months implantation period, there was an improvement in CAL and reduction in PD along with bone fill was observed.

scholarly journals CONE BEAM COMPUTED TOMOGRAPHY AS A TOOL FOR THE ANALYSIS OF BONE FILL IN INTRABONY DEFECTS WITH USE OF NANOGENTM BONE GRAFT

2021 ◽  
Vol 9 (06) ◽  
pp. 549-558
Author(s):  
Bangaru Mounika ◽  
Ajay Reddy P. ◽  
Sanjay Vasudevan ◽  
Vaishnavi a ◽  
Sunny Rajoria ◽  
...  
Keyword(s):  
Bone Graft ◽  
Plaque Index ◽  
Base Line ◽  
Intrabony Defects ◽  
Clinical Attachment Level ◽  
Radiographic Parameters ◽  
Probing Depth ◽  
Defect Sites ◽  
The Mean ◽  
Attachment Level

Aims and Objectives-The aim of the present study was to evaluate the regenerative potential of synthetic nanocrystalline calcium sulphate bone graft (NANOGENTM) in treatment of intrabony defect both clinically and radiographically. Materials and Methods- Study was conducted in 10 patients with 10 defect sites with probing pocket depth >5mm with radiographs at base line were selected. All the sites with intrabony defects treated with NanogenTM bone graft and follow up was done for 3 months and 6 months respectively. Clinical parameters included in the study are of plaque index, probing depth (PD), clinical attachment level (CAL), Sulcus bleeding index (SBI). Radiographic parameters include bone fill. Results-In the present study, the mean clinical attachment loss, plaque index, probing depth index, sulcus bleeding index at baseline was 9.11±1.054, 1.5278±1.9543, 8.44±1.130, 3.7222±.77504 respectively, reduced to 5.7±1.093,.6389±.37731,3.67±.500,1.2222±.75462 respectively at the end of the 3 months.5.00±.707, .4167±.39528, 2.78±.667, .4167±.46771 respectively at the end of the 6 months. The mean bone fill baseline was 9.11 ± 1.054 mm which was reduced to 5.78 ± 1.093 mm at 3 months and reduced to 5.00 ± 0.707 mm at 6 months, showing a bone fill of 3.933 ± 0.3640 mm by the end of three months and 4.256 ± 0.3678 by the end of six months which were statistically significant (P=0.002). Conclusion- Present study, evidenced that reduction in probing depths, gain in clinical attachment level and bone fill. Improvement of clinical and radiographic parameters at sites treated with NanogenTM.

scholarly journals Evaluation of the Efficiency of Modified Bone Graft in Putty Consistency in Treatment of Angular Bone Defect - A Pilot Study

2019 ◽  
Vol 4 (12) ◽  
Author(s):  
Ramnath Elangovan ◽  
Mejalla Muthiah Amaladhas ◽  
Ramakrishnan Theyagarajan ◽  
Sivaranjani Pandithurai
Keyword(s):  
Pilot Study ◽  
Bone Graft ◽  
Bone Defects ◽  
Graft Material ◽  
Clinical Attachment Level ◽  
Probing Depth ◽  
Bone Level ◽  
Distal Aspect ◽  
Attachment Level ◽  
Depth Reduction

Background: Periodontitis is the inflammatory disease of the periodontium which leads to destruction of the supporting bone and periodontium. Colocast is a bovine derived bone graft. This colocast when processed in a putty consistency constitutes the modified colocast. Aim: The aim is to evaluate the clinical efficiency of consistency modified bone graft material in the treatment of angular bone defects. Materials and Methods: Five patients with angular bone defects were included in this study. Bone defects were treated with bone grafts in putty consistency. Probing depth, clinical attachment level along with mesial and distal bone level were evaluated at baseline and three months after surgery. Results: There was a clinically and statistically considerable Probing depth reduction, Clinical Attachment Level gain and increase in bone formation at both mesial and distal aspect of treated teeth. Conclusions: The Modified bone graft in putty consistency has been proven to be effective in managing angular bone defects along with ease at handling the graft in this study.

scholarly journals Surgical Treatment of Periodontal Intrabony Defects with Calcium Sulphate in Combination with Beta-Tricalcium Phosphate: Clinical Observations Two Years Post-Surgery

2011 ◽  
Vol 54 (1) ◽  
pp. 13-20 ◽  
Author(s):  
Sujith Sukumar ◽  
Ivo Dřízhal ◽  
Vladimíra Paulusová ◽  
Josef Bukač
Keyword(s):  
Tricalcium Phosphate ◽  
Gingival Recession ◽  
Calcium Sulphate ◽  
Intrabony Defects ◽  
Clinical Attachment Level ◽  
Post Surgery ◽  
Beta Tricalcium Phosphate ◽  
Probing Depth ◽  
Study Results ◽  
Attachment Level

The study was designed to evaluate the clinical outcome of a composite material, beta-tricalcium phosphate in combination with calcium sulphate, in the treatment of periodontal intrabony defects. The combination of these materials is believed to aid in guided tissue regeneration owing to their properties. A total of 47 teeth with intrabony defects in 26 periodontitis patients were treated with Fortoss® Vital (Biocomposites, Staffordshire, UK). Clinical parameters were evaluated which included changes in probing depth, clinical attachment level/loss and gingival recession at the baseline and 2 years postoperatively. The mean differences in measurements between the baseline and 2 years postoperatively were a reduction of 2.07±1.14 mm (p=0.000) in case of probing depth and a gain of 1.93±1.36 mm (p=0.000) in clinical attachment level; but an increase of 0.14±0.73 mm (p=0.571) in gingival recession. The study results show that the treatment with a combination of beta tricalcium phosphate and calcium sulphate led to a significantly favorable clinical improvement in periodontal intrabony defects 2 years after the surgery.

scholarly journals A 12-month randomized controlled trial evaluating erythritol air-polishing versus curette/ultrasonic debridement of mandibular furcations in supportive periodontal therapy

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ingvild M. Ulvik ◽  
Terje Sæthre ◽  
Dagmar F. Bunæs ◽  
Stein Atle Lie ◽  
Morten Enersen ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Clinical Attachment Level ◽  
Treatment Difference ◽  
Randomized Controlled ◽  
Air Polishing ◽  
Probing Depth ◽  
Furcation Defects ◽  
Supportive Periodontal Therapy ◽  
Attachment Level

Abstract Background Due to complex morphology and limited access, the cleaning of the furcation area is extremely challenging. Therefore, novel therapeutic approaches need to be tested to potentially overcome debridement limitations. The aim of the present prospective 12-month study was to compare clinical and microbiological effects following erythritol air-polishing versus conventional mechanical debridement of furcation defects in a cohort of periodontal maintenance patients. Methods Twenty patients with grade II mandibular molar furcation defects volunteered to enroll in this single-centre, examiner masked, randomized controlled trial. In a split-mouth study design, two furcation sites in each patient were randomly assigned to either receive subgingival debridement using erythritol air-polishing (test) or conventional ultrasonic/curette debridement (control) at baseline, and at 3, 6, 9 and 12 months. Probing depth, clinical attachment level and bleeding on probing were recorded at 3-month intervals. Subgingival microbiological samples obtained at baseline, 6 and 12 months were analyzed using checkerboard DNA–DNA hybridization. Discomfort from treatment was scored at 12 months using a visual analogue scale. The differences between treatments, and time-points, were tested using multilevel analysis (mixed effect models and robust variance estimates). Results A significant reduction in probing depth took place following both treatments (p < 0.001). Control sites experienced a significant mean gain in clinical attachment level of 0.5 mm (± 0.2) (p = 0.004), whereas a non-significant gain of 0.4 mm (± 0.3) was observed at test sites (p = 0.119). At 6 months, a significant between-treatment difference of 0.8 mm (± 0.4) was observed in favor of the control (p = 0.032). No significant between-treatment differences were observed in microbial load or composition. Notably, at 12 months patients experienced significantly less discomfort following air-polishing compared with control (p = 0.001). Conclusions The 12-month observations indicate that erythritol air-polishing and conventional mechanical debridement both support clinical improvements. A significant between-treatment difference in clinical attachment level was, however, detected in favour of control debridement at 6 months. In terms of patient comfort, erythritol air-polishing is superior. Trial Registration: The clinical trial was retrospectively registered in ClinicalTrial.gov with registration NCT04493398 (07/28/2020).

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