A longitudinal and prospective study of Epstein-Barr virus load in AIDS-related non-Hodgkin lymphoma

2006 ◽  
Vol 36 (4) ◽  
pp. 258-263 ◽  
Author(s):  
Fabrice Bonnet ◽  
Anne-Christine Jouvencel ◽  
Marie Parrens ◽  
Magali Joblon Leon ◽  
Emmanuelle Cotto ◽  
...  
Keyword(s):  
Prospective Study ◽  
Hodgkin Lymphoma ◽  
Epstein Barr Virus ◽  
Virus Load ◽  
Barr Virus ◽  
Non Hodgkin Lymphoma ◽  
Epstein Barr

scholarly journals Epstein–Barr virus load is higher in long‐term Hodgkin lymphoma survivors compared to their unaffected twins and unrelated controls

2018 ◽  
Vol 185 (2) ◽  
pp. 377-380 ◽  
Author(s):  
Amie E. Hwang ◽  
Vickie Marshall ◽  
David V. Conti ◽  
Bharat N. Nathwani ◽  
Thomas M. Mack ◽  
...  
Keyword(s):  
Hodgkin Lymphoma ◽  
Epstein Barr Virus ◽  
Virus Load ◽  
Barr Virus ◽  
Epstein Barr ◽  
Lymphoma Survivors

scholarly journals Subtypes of Epstein-Barr virus in human immunodeficiency virus- associated non-Hodgkin lymphoma

Blood ◽  
1991 ◽  
Vol 78 (11) ◽  
pp. 3004-3011 ◽  
Author(s):  
MJ Boyle ◽  
WA Sewell ◽  
TB Sculley ◽  
A Apolloni ◽  
JJ Turner ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Hodgkin Lymphoma ◽  
Epstein Barr Virus ◽  
Type I ◽  
Type B ◽  
Barr Virus ◽  
Non Hodgkin Lymphoma ◽  
Immunodeficiency Virus ◽  
High Prevalence ◽  
Epstein Barr

Abstract Biopsy samples obtained from 20 patients with human immunodeficiency virus (HIV)-associated non-Hodgkin lymphoma (NHL) were assessed for evidence of Epstein-Barr virus (EBV) and HIV sequences. DNA was extracted from formalin-fixed, paraffin-embedded NHL tissue and specific viral gene sequences were sought using the polymerase chain reaction (PCR). EBV sequences were found in 10 NHL samples (50%), with five tumors showing A-type and five B-type sequences. By serologic testing, 18 of 19 patients had antibodies to EBV, with 14 patients having antibodies to A-type EBV and 11 to B-type EBV. Serology confirmed the high prevalence of type B EBV in HIV-infected patients, but was not a reliable indicator of the EBV subtype present in the lymphomas. HIV sequences were present in biopsy tissue but at a level consistent with an origin from bystander HIV-infected cells. All 20 patients were negative by enzyme-linked immunosorbent assay for antibodies to human T-cell leukemia virus-type I. The high prevalence of type B EBV in these tumors is similar to the findings in endemic Burkitt's lymphoma, where 40% of the tumors have type B viral sequences. In normal populations, type B EBV is rarely found outside the nasopharynx. These studies support the hypothesis that EBV is an important cofactor in NHL in HIV-infected persons. The finding that B- type EBV is present in 25% of HIV-associated NHL suggests that this EBV subtype may be an important human pathogen with a wider geographic distribution than originally thought.

Epstein-Barr virus–associated B-cell non-Hodgkin lymphoma following treatment of hairy cell leukemia with cladribine

Blood ◽  
2003 ◽  
Vol 102 (9) ◽  
pp. 3457-3458 ◽  
Author(s):  
Georg Lenz ◽  
Alexander Golf ◽  
Thomas Rüdiger ◽  
Wolfgang Hiddemann ◽  
Torsten Haferlach
Keyword(s):  
B Cell ◽  
Hodgkin Lymphoma ◽  
Hairy Cell Leukemia ◽  
Epstein Barr Virus ◽  
Hairy Cell ◽  
Cell Leukemia ◽  
Barr Virus ◽  
Non Hodgkin Lymphoma ◽  
Epstein Barr
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