Volumetric, ultrasonic and UV absorption studies on interactions of antibiotic drug chloramphenicol with glycine and its dipeptide in aqueous solutions at T = (288.15–318.15) K

2016 ◽  
Vol 99 ◽  
pp. 16-29 ◽  
Author(s):  
Harsh Kumar ◽  
Isha Behal
Keyword(s):  
Aqueous Solutions ◽  
Uv Absorption ◽  
Antibiotic Drug ◽  
Absorption Studies

scholarly journals Study of Molecular Interaction for Antibiotic Drug with Sugar Solutions at Different Temperature

2020 ◽  
Vol 10 (01) ◽  
pp. 170-174 ◽  
Author(s):  
Sundus H. Merza ◽  
Nagham H. Abood ◽  
Ahamed M. Abbas
Keyword(s):  
Aqueous Solutions ◽  
Molar Volume ◽  
Atmospheric Pressure ◽  
Apparent Molar Volume ◽  
Viscosity Data ◽  
Free Energy Of Activation ◽  
Ternary Solutions ◽  
Antibiotic Drug ◽  
Solute Interactions ◽  
Molar Expansibility

The interactions of drug amoxicillin with maltose or galactose solutions with a variation of temperature have been discussed by taking in the volumetric and viscometric procedures. Physical properties [densities (ρ) and viscosities (η)] of amoxicillin (AMOX) aqueous solutions and aqueous solutions of two type saccharides (maltose and galactose 0.05m) have been measured at T = (298.15, 303.15 and 308.15) K under atmospheric pressure. The apparent molar volume (ϕv cm3mole-1) has been evaluated from density data and fitted to a Redlich-Mayer equation. The empirical parameters of the Mayer-Redlich equation and apparent molar volume at infinite dilution Ø°v were explicated in terms of interactions from type solute-solvent and solute–solute interactions. Transfer molar volume ΔtraØ°v for AMOX from water to aqueous maltose and galactose solutions were calculated to comprehend different interactions in the ternary solutions. Limiting apparent molar expansibility (Ø°E) and Hepler’s coefficient was also calculated to indicate the structure making ability of AMOX in the ternary solutions. Jones–Dole coefficient B and A have been calculated from viscosity data by employing the Jones–Dole equation. The free energy of activation of viscous flow per mole of the solute (Δμ°2*) and solvent (Δμ°1*) have been explained on the basis of the Eyring and Feakins equation.

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