ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery

2006 ◽  
Vol 32 (3) ◽  
pp. 396-406 ◽  
Author(s):  
David V. Seal ◽  
Peter Barry ◽  
George Gettinby ◽  
Fiona Lees ◽  
Magnus Peterson ◽  
...  
Keyword(s):  
Cataract Surgery ◽  
Postoperative Endophthalmitis

Outsourced cataract surgery and postoperative endophthalmitis

2013 ◽  
Vol 91 (8) ◽  
pp. 701-708 ◽  
Author(s):  
Søren Solborg Bjerrum ◽  
Jens F. Kiilgaard ◽  
Kim L. Mikkelsen ◽  
Morten la Cour
Keyword(s):  
Cataract Surgery ◽  
Postoperative Endophthalmitis

Prophylaxis Against Postoperative Endophthalmitis in Cataract Surgery

2011 ◽  
Vol 51 (4) ◽  
pp. 67-83 ◽  
Author(s):  
Glenn Yiu ◽  
Lucy Young ◽  
Michael Gilmore ◽  
James Chodosh
Keyword(s):  
Cataract Surgery ◽  
Postoperative Endophthalmitis

scholarly journals Outbreak of Multidrug-resistant Pseudomonas Aeruginosa Endophthalmitis Due to Contaminated Trypan Blue Solution

2019 ◽  
Author(s):  
Pritam Bawankar ◽  
Harsha Bhattacharjee ◽  
Manabjyoti Barman ◽  
Ronel Soibam ◽  
Hemalata Deka ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Cataract Surgery ◽  
Genomic Dna ◽  
Trypan Blue ◽  
Dna Typing ◽  
Multidrug Resistant ◽  
Diffusion Method ◽  
Postoperative Endophthalmitis ◽  
Retrospective Case ◽  
Multiple Drugs

Purpose: To report the investigation of an outbreak of multidrug-resistant (MDR) Pseudomonas aeruginosa endophthalmitis in 13 patients after cataract surgery and to emphasize on the importance of clinical profile, risk factors, and treatment outcomes. Methods: This was a hospital-based, retrospective case study with 13 consecutive patients who had manual small-incision cataract surgery with intraocular lens (IOL) implantation and developed acute postoperative Pseudomonas aeruginosa endophthalmitis. The anterior chamber taps, vitreous aspirates, and environmental surveillance specimens were inoculated for culturing. Antibiotic susceptibility testing was performed using the agar diffusion method. Pulsed-field gel electrophoresis (PFGE) was used to determine the relationship between bacterial isolates recovered from study patients and contaminated surveillance samples. Results: Pseudomonas aeruginosa was isolated from all 13 eyes with acute postoperative endophthalmitis and the trypan blue solutions used during surgery. Sensitivity tests revealed that all isolates had an identical resistance to multiple drugs and were only susceptible to imipenem. Genomic DNA typing of Pseudomonas aeruginosa isolates recovered from patients and trypan blue solutions showed an identical banding pattern on the PFGE. Despite the prompt use of intravitreal antibiotics and early vitrectomy with IOL explantation in some patients, the outcome was poor in about 50% of patients. Conclusion: Positive microbiology and genomic DNA typing results proved that the contaminated trypan blue solutions were the source of infection in this outbreak. Postoperative endophthalmitis caused by Pseudomonas aeruginosa is often associated with a poor visual prognosis despite prompt treatment with intravitreal antibiotics.

scholarly journals Outbreak of postoperative endophthalmitis caused by Pseudomonas aeruginosa: a case report and brief literature review

2021 ◽  
Vol 49 (11) ◽  
pp. 030006052110553
Author(s):  
Kasra Cheraqpour ◽  
Aliasghar Ahmadraji ◽  
Seyed Ali Tabatabaei ◽  
Bahram Bohrani Sefidan ◽  
Mohammad Soleimani ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Visual Acuity ◽  
Cataract Surgery ◽  
Clinical Findings ◽  
Postoperative Endophthalmitis ◽  
Causative Pathogen ◽  
Light Perception ◽  
Strict Adherence ◽  
Gram Negative ◽  
Source Of Infection

Endophthalmitis is the most serious complication of cataract surgery. A cluster of endophthalmitis is a devastating event for surgeons. Pseudomonas aeruginosa is the main causative pathogen of Gram-negative endophthalmitis, which can be suggestive of the occurrence of an outbreak. Ten patients diagnosed with endophthalmitis after cataract surgery performed by one surgeon were analyzed in this study. At presentation, five patients had obvious clinical findings of endophthalmitis with visual acuity of light perception, two patients had poor light perception/no light perception of vision complicated by concomitant keratitis, and three patients had earlier signs of infection (e.g., a lower degree of anterior chamber and vitreous cells, better presenting visual acuity, and greater visibility of the fundus). Investigations revealed that the source of infection was growth of P. aeruginosa on the phaco probe. All of the surgeries had been performed by the same contaminated probe without sterilization between surgeries. This finding emphasizes the importance of strict adherence to sterility protocols during high-risk surgeries such as intraocular surgeries. Additionally, this report aims to emphasize to surgeons that negligence of simple but vital steps of sterility for any reason, such as limitations in time or equipment, can lead to catastrophic events.

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