scholarly journals Intraosseous infiltrations of Platelet-Rich Plasma for severe hip osteoarthritis: A pilot study

2020 ◽  
Vol 11 ◽  
pp. S585-S590
Author(s):  
Nicolás Fiz ◽  
Diego Delgado ◽  
Ane Garate ◽  
Pello Sánchez ◽  
Jaime Oraa ◽  
...  
Keyword(s):  
Pilot Study ◽  
Platelet Rich Plasma ◽  
Hip Osteoarthritis

627-P: Efficacy and Safety of Allogeneic Platelet Rich Plasma in Treatment of Diabetic Patients with Lower Limb Ulcers: A Pilot Study

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 627-P
Author(s):  
WUQUAN DENG ◽  
MIN HE ◽  
BING CHEN ◽  
YU MA ◽  
DAVID ARMSTRONG ◽  
...  
Keyword(s):  
Pilot Study ◽  
Lower Limb ◽  
Platelet Rich Plasma ◽  
Diabetic Patients ◽  
Efficacy And Safety

scholarly journals Feasibility of exercise and weight management for people with hip osteoarthritis and overweight or obesity: a pilot study

2021 ◽  
pp. 100174
Author(s):  
Michelle Hall ◽  
Libby Spiers ◽  
Gabrielle Knox ◽  
Rana S. Hinman ◽  
Priya Sumithran ◽  
...  
Keyword(s):  
Pilot Study ◽  
Weight Management ◽  
Hip Osteoarthritis ◽  
Overweight Or Obesity

Investigation of platelet-rich plasma in rabbit cranial defects: A pilot study

2002 ◽  
Vol 60 (10) ◽  
pp. 1176-1181 ◽  
Author(s):  
Tara L. Aghaloo ◽  
Peter K. Moy ◽  
Earl G. Freymiller
Keyword(s):  
Pilot Study ◽  
Platelet Rich Plasma

scholarly journals Intra-articular saline injection as effective as corticosteroids, platelet-rich plasma and hyaluronic acid for hip osteoarthritis pain: a systematic review and network meta-analysis of randomised controlled trials

2020 ◽  
pp. bjsports-2020-102179
Author(s):  
Aaron Gazendam ◽  
Seper Ekhtiari ◽  
Anthony Bozzo ◽  
Mark Phillips ◽  
Mohit Bhandari
Keyword(s):  
Systematic Review ◽  
Functional Outcomes ◽  
Randomised Controlled Trials ◽  
Platelet Rich Plasma ◽  
Meta Analysis ◽  
Hip Osteoarthritis ◽  
Controlled Trials ◽  
Saline Injection ◽  
Randomised Controlled ◽  
Indirect Comparisons

ObjectiveIntra-articular (IA) injections represent a commonly used modality in the treatment of hip osteoarthritis (OA). Commonly used injections include corticosteroids (CCS), hyaluronic acid (HA) and platelet-rich plasma (PRP). A network meta-analysis allows for comparison among more than two treatment arms and uses both direct and indirect comparisons between interventions. The objective of this network meta-analysis is to compare the efficacy of the various IA injectable treatments in treating hip OA at up to 6 months of follow-up.DesignThis is a systematic review and network meta-analysis. Bayesian random-effects model was performed to assess the direct and indirect comparisons of all treatment options.Data sourcesPubMed, Embase, Cochrane Central Register of Controlled Trials, Scopus and Web of Science, from inception to October 2019.Eligibility criteria for selected studiesRandomised controlled trials assessing the efficacy of CCS, HA, PRP and placebo in the form of IA saline injection for patients with hip OA.ResultsEleven randomised controlled trials comprising 1353 patients were included. For pain outcomes at both 2–4 and 6 months, no intervention significantly outperformed placebo IA injection. For functional outcomes at both 2–4 and 6 months, no intervention significantly outperformed placebo IA injection. Regarding change from baseline at 2–4 months and 6 months, pooled data demonstrated that all interventions (including placebo), with the exception of HA+PRP, led to a clinically important improvement in both pain, exceeding the minimal clinically important difference.ConclusionEvidence suggests that IA hip saline injections performed as well as all other injectable options in the management of hip pain and functional outcomes.

scholarly journals Reactivating Ovarian Function through Autologous Platelet-Rich Plasma Intraovarian Infusion: Pilot Data on Premature Ovarian Insufficiency, Perimenopausal, Menopausal, and Poor Responder Women

2020 ◽  
Vol 9 (6) ◽  
pp. 1809 ◽  
Author(s):  
Konstantinos Sfakianoudis ◽  
Mara Simopoulou ◽  
Sokratis Grigoriadis ◽  
Agni Pantou ◽  
Petroula Tsioulou ◽  
...  
Keyword(s):  
Pilot Study ◽  
Outcome Measures ◽  
Primary Outcome ◽  
Platelet Rich Plasma ◽  
Premature Ovarian Insufficiency ◽  
Cycle Performance ◽  
Routine Practice ◽  
Ovarian Insufficiency ◽  
Pilot Studies ◽  
Pilot Data

Intraovarian platelet-rich plasma (PRP) infusion was recently introduced in the context of addressing ovarian insufficiency. Reporting on its effectiveness prior to adopting in clinical routine practice is imperative. This study aims to provide pilot data regarding PRP application for ovarian rejuvenation. Four pilot studies were conducted on poor ovarian response (POR), premature ovarian insufficiency (POI), perimenopause, and menopause, respectively. Each pilot study reports on thirty patients, 120 participants were recruited in total. All participants provided written informed consent prior to treatment. Primary outcome measures for the POR pilot study were levels of anti-müllerian hormone (AMH), antral follicle count (AFC) and oocyte yield. For the POI, perimenopausal and menopausal pilot studies primary outcome measures were restoration of menstrual cycle, and Follicle Stimulating Hormone (FSH) levels. A significant improvement on the hormonal profile and the ovarian reserve status was noted, along with improved intracytoplasmic sperm injection (ICSI) cycle performance concerning POR participants. Menstruation recovery was observed in 18 out of 30 POI patients, along with a statistically significant improvement on levels of AMH, FSH, and AFC. Similarly, 13 out of 30 menopausal women positively responded to PRP treatment. Finally, menstruation regularity, improved hormonal levels and AFC were reported for 24 out of 30 perimenopausal women. To conclude, PRP infusion appears to convey promising results in addressing ovarian insufficiency.

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