Magnetic Active Agent Release System (MAARS): Evaluation of a new way for a reproducible, externally controlled drug release into the small intestine

2012 ◽  
Vol 161 (3) ◽  
pp. 722-727 ◽  
Author(s):  
Christian T. Dietzel ◽  
Hendryk Richert ◽  
Sandra Abert ◽  
Ute Merkel ◽  
Marion Hippius ◽  
...  
Keyword(s):  
Small Intestine ◽  
Drug Release ◽  
Active Agent ◽  
Controlled Drug Release ◽  
Release System

Reducing the Risk in Controlled Drug Release by Using Tannic Acid in Liposomal Formulations

2018 ◽  
Vol 68 (12) ◽  
pp. 2925-2918
Author(s):  
Gabriela Cioca ◽  
Maricel Agop ◽  
Marcel Popa ◽  
Simona Bungau ◽  
Irina Butuc
Keyword(s):  
Drug Release ◽  
Tannic Acid ◽  
Release Rate ◽  
Controlled Drug Release ◽  
Toxicity Threshold ◽  
Release System ◽  
Liposomal Formulations ◽  
Cross Linker ◽  
Natural Cross

One of the main challenges in designing a release system is the possibility to control the release rate in order to maintain it at a constant value below a defined limit, to avoid exceeding the toxicity threshold. We propose a method of overcoming this difficulty by introducing the drug into liposomes, prior to its inclusion in the hydrogel. Furthermore, a natural cross linker (as is tannic acid) is used, instead of the toxic cross linkers commonly used, thus reducing the toxicity of the release system as a whole.

Mathematical solution for controlled drug release from a swelling hydrogel to the small intestine

2019 ◽  
Author(s):  
Amanina Setapa ◽  
Shalela Mohd Mahali ◽  
Ummu ‘Atiqah Mohd Roslan ◽  
Nur Fadhilah Ibrahim
Keyword(s):  
Small Intestine ◽  
Drug Release ◽  
Controlled Drug Release ◽  
Mathematical Solution

Precise and tunable time-controlled drug release system using layer-by-layer films as erodible coatings

2020 ◽  
Vol 116 ◽  
pp. 111244
Author(s):  
Jiafeng Tian ◽  
Rong Xu ◽  
Haozheng Wang ◽  
Ying Guan ◽  
Yongjun Zhang
Keyword(s):  
Drug Release ◽  
Controlled Drug Release ◽  
Layer By Layer ◽  
Release System ◽  
Drug Release System
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