Mother–father differences in screening for developmental delay in infants and toddlers

2012 ◽  
Vol 45 (4) ◽  
pp. 255-262 ◽  
Author(s):  
Maja Cepanec ◽  
Karolina Lice ◽  
Sanja Šimleša
Keyword(s):  
Developmental Delay ◽  
Infants And Toddlers

Developmental delay in infants and toddlers with sickle cell disease: a systematic review

2021 ◽  
Author(s):  
Catherine R Hoyt ◽  
Taniya E Varughese ◽  
Jeni Erickson ◽  
Natalie Haffner ◽  
Lingzi Luo ◽  
...  
Keyword(s):  
Systematic Review ◽  
Sickle Cell Disease ◽  
Developmental Delay ◽  
Sickle Cell ◽  
Infants And Toddlers ◽  
Cell Disease

Emergence of Developmental Delay in Infants and Toddlers With an FMR1 Mutation

PEDIATRICS ◽  
2021 ◽  
Vol 147 (5) ◽  
pp. e2020011528
Author(s):  
Anne C. Wheeler ◽  
Angela Gwaltney ◽  
Melissa Raspa ◽  
Katherine C. Okoniewski ◽  
Elizabeth Berry-Kravis ◽  
...  
Keyword(s):  
Developmental Delay ◽  
Infants And Toddlers

Neurdevelopmental Deficits Among 80 Infants and Toddlers with Sickle Cell Disease

Blood ◽  
2011 ◽  
Vol 118 (21) ◽  
pp. 174-174
Author(s):  
Tara Brennan ◽  
Penny Glass ◽  
Christen Meisel ◽  
Brenda Martin ◽  
Lori Luchtman-Jones ◽  
...  
Keyword(s):  
Primary Care ◽  
Sickle Cell Disease ◽  
Developmental Delay ◽  
Sickle Cell ◽  
Maternal Education ◽  
College Graduates ◽  
Cell Phenotype ◽  
Infants And Toddlers ◽  
Education Attainment ◽  
Cell Disease

Abstract Abstract 174FN2 Introduction: Neurocognitive deficits by school age in children with sickle cell disease (SCD), with and without a history of stroke, has been well established. However, little is understood with respect to the onset and course of these deficits in early childhood and how these may relate to SES and disease status. We are undertaking a 4-year mixed cross-sectional longitudinal study of early neurodevelopmental status in children younger than 4 years of age with SCD. The primary aims are to: (1) characterize the prevalence and nature of the developmental deficits in infants and toddlers while controlling for socio-economic status (SES); (2) examine the moderating effects of sickle cell phenotype, hematologic severity, and parent characteristics on developmental outcome. The current presentation is based on the first 80 baseline neurodevelopmental evaluations. Patients and Methods: Children 3 ½ years of age or younger with SCD of any phenotype were eligible to participate. Comprehensive neurodevelopmental evaluations using the Bayley Scales of Infant Development were conducted when the child reached specific age levels (9, 15, 21, 30, and 40 months), with an ultimate planned sample size of a minimum of 45 children with SCD at each of the five age levels. Demographics and data regarding phenotype, hematologic variables, and occurrence of pain crises were obtained separately. Results: To date, 199 children have been enrolled in the study. We have conducted 205 evaluations and completed data analysis of the baseline data for 80 patients. Of those 80, phenotype distribution was representative of the sickle cell population (HbSS=56%, HbSC=31%). Gender was balanced (51% female). As expected, race/ethnicity of most children was African/African American (95%), about 5% Hispanic/Biracial. Maternal education attainment was high, as almost half of the mothers (48%) were college graduates. Mean Mental Index was 84.2 (sd=13.5) and Motor Index was 89.1 (sd=14.4) (compared to published norm means of 100, sd=15). Fourteen children (17.5%) had a significant delay (Index score > 2 sd below the mean) on either the Mental or Motor Index, with 7 children significantly delayed on both. Lower SES, based on maternal education attainment, was not sufficient to explain developmental delay. Poor performance was present in 10% of children whose mothers were college graduates. Male children were at significantly greater risk for delays, controlling for SES, pain crisis, pneumonia/ACS, and %hemoglobin. Odds ratio of significant developmental delay was >9 times more likely among those who had vaso-occlusive pain episode, controlling for SES, gender, pneumonia/ACS, and hemoglobin concentration. Of note, none of the children had been identified as delayed by their primary care physician or sickle cell provider. Conclusions: Early cognitive and motor delays are present in SCD and not sufficiently explained by lower SES. Increased vulnerability of male gender is consistent with other at-risk populations, but has not been previously addressed in SCD research. Significant developmental delay in children with chronic illness may go unrecognized by primary care practices, medical specialty clinics, or parents. The importance of routine neurodevelopmental assessment for children with chronic medical disease, and SCD in particular, is clear. This study was funded by the NHLBI as a Patient Services Project within the Washington Area Comprehensive Sickle Cell Center. Disclosures: No relevant conflicts of interest to declare.

scholarly journals A comparison of the performance of normal middle social class Egyptian infants and toddlers with the reference norms of the Bayley Scales -third edition (Bayley III): A pilot study

PLoS ONE ◽  
2021 ◽  
Vol 16 (12) ◽  
pp. e0260138
Author(s):  
Ebtissam M. Salah El-Din ◽  
Zeinab M. Monir ◽  
Manal A. Shehata ◽  
Marwa W. Abouelnaga ◽  
Mones M. Abushady ◽  
...  
Keyword(s):  
Social Class ◽  
Pilot Study ◽  
Developmental Delay ◽  
Developmental Trajectory ◽  
Socioeconomic Background ◽  
Infants And Toddlers ◽  
Developmental Assessment ◽  
Egyptian Children ◽  
Composite Scores ◽  
Bayley Scales

Background Developmental assessment is an important facility for early detection and intervention of developmental delay in children. Objective: to assess the performance of a sample of middle social class Egyptian infants and toddlers on Bayley Scales of Infant and Toddler Development-third edition (Bayley III), and to compare their cognitive, motor, and communication scores with that of the reference norms. Methods It was a cross-sectional pilot study, included 270 children aged 18–42 months. Mothers filled a questionnaire including questions about family socioeconomic background, perinatal history, and family history. Physical examination and growth assessment of children were performed. Developmental assessment of cognitive, language and motor skills was performed using the Bayley III scales and compared the American norm scores with the Egyptian mean scores. Results The mean cognitive, language and motor composite scores were 92.5+18.5, 91.76+ 15.6, and 95.67+18.9 respectively. All were lower than the American mean (100+ 15) with highly significant differences. About one-fourth of the enrolled Egyptian children had below-average composite scores according to the US cutoff point. The ranks of Egyptian children on the American versus the Egyptian percentile curves were significantly different. Conclusion Mean values of all assessed developmental domains of Egyptian children are within the norm-referenced average of Bayley III, but lower than the recorded American mean. Assessing Egyptian children according to the American norms may result in overestimating developmental delay. This pilot study raised the question about using different cutoff points suitable for the developmental trajectory of Egyptian children. Answering this question needs further studies on Bayley-III after cultural adaptation and standardization, using a larger, more diverse, and representative sample of the Egyptian population.

Global Developmental Delay and Its Determinants Among Urban Infants and Toddlers: A Cross Sectional Study

2010 ◽  
Vol 77 (9) ◽  
pp. 975-980 ◽  
Author(s):  
Sandeep Sachdeva ◽  
Ali Amir ◽  
Seema Alam ◽  
Zulfia Khan ◽  
Najam Khalique ◽  
...  
Keyword(s):  
Developmental Delay ◽  
Cross Sectional Study ◽  
Global Developmental Delay ◽  
Infants And Toddlers ◽  
Sectional Study ◽  
Cross Sectional

Risk Factors for Developmental Delay Among Infants and Toddlers

1992 ◽  
Vol 21 (1) ◽  
pp. 39-52 ◽  
Author(s):  
Ellen H. King ◽  
Deborah A. Logsdon ◽  
Stephen R. Schroeder
Keyword(s):  
Risk Factors ◽  
Developmental Delay ◽  
Infants And Toddlers

Maltreated Infants and Toddlers: Predictors of Developmental Delay

2009 ◽  
Vol 30 (6) ◽  
pp. 489-498 ◽  
Author(s):  
Anita A. Scarborough ◽  
E Christopher Lloyd ◽  
Richard P. Barth
Keyword(s):  
Developmental Delay ◽  
Infants And Toddlers
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