Bone engineering with adipose tisssue derived stromal cells

2006 ◽  
Vol 34 (8) ◽  
pp. 466-471 ◽  
Author(s):  
Konstanze Weinzierl ◽  
Alexander Hemprich ◽  
Bernhard Frerich
Keyword(s):  
Stromal Cells ◽  
Bone Engineering

Effective Bone Engineering with Periosteum-derived Cells

2007 ◽  
Vol 86 (1) ◽  
pp. 79-83 ◽  
Author(s):  
H. Agata ◽  
I. Asahina ◽  
Y. Yamazaki ◽  
M. Uchida ◽  
Y. Shinohara ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Stromal Cells ◽  
Bone Marrow Stromal Cells ◽  
Combined Treatment ◽  
Cell Types ◽  
Marrow Stromal Cells ◽  
Osteogenic Potential ◽  
Bone Engineering ◽  
Periosteal Cells ◽  
Pre Treatment

Bone augmentation via tissue engineering has generated significant interest. We hypothesized that periosteum-derived cells could be used in place of bone marrow stromal cells (which are widely used) in bone engineering, but the differences in osteogenic potential between these 2 cell types are unclear. Here, we compared the osteogenic potential of these cells, and investigated the optimal osteoinductive conditions for periosteum-derived cells. Both cell types were induced, via bFGF and BMP-2, to differentiate into osteoblasts. Periosteal cells proliferated faster than marrow stromal cells, and osteogenic markers indicated that bone marrow stromal cells were more osteogenic than periosteal cells. However, pre-treatment with bFGF made periosteal cells more sensitive to BMP-2 and more osteogenic. Transplants of periosteal cells treated with BMP-2 after pre-treatment with bFGF formed more new bone than did marrow stromal cells. Analysis of these data suggests that combined treatment with bFGF and BMP-2 can make periosteum a highly useful source of bone regeneration.

Human bone marrow stromal cells: In vitro expansion and differentiation for bone engineering

Biomaterials ◽  
2006 ◽  
Vol 27 (36) ◽  
pp. 6150-6160 ◽  
Author(s):  
G. Ciapetti ◽  
L. Ambrosio ◽  
G. Marletta ◽  
N. Baldini ◽  
A. Giunti
Keyword(s):  
Bone Marrow ◽  
Stromal Cells ◽  
Bone Marrow Stromal Cells ◽  
Marrow Stromal Cells ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Bone Engineering ◽  
In Vitro Expansion

1428: Influence of Prostatic Epithelium on Proliferation and Differentiation of Stromal Cells

2005 ◽  
Vol 173 (4S) ◽  
pp. 387-387
Author(s):  
Quan Wu ◽  
Jian-Dang Shi ◽  
Yu Liu ◽  
Ke-Ming Wang ◽  
Helmut Klocker ◽  
...  
Keyword(s):  
Stromal Cells ◽  
Proliferation And Differentiation ◽  
Prostatic Epithelium
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