scholarly journals Is There a Place for Surgical Aortic Valve Replacement in Patients With Aortic Stenosis and Previous Coronary Bypass Grafting?

2016 ◽  
Vol 9 (20) ◽  
pp. 2144-2146 ◽  
Author(s):  
Fadi J. Sawaya ◽  
Ole De Backer
2016 ◽  
Vol 25 (11) ◽  
pp. 1118-1123 ◽  
Author(s):  
Tom Kai Ming Wang ◽  
David H.M. Choi ◽  
Tharumenthiran Ramanathan ◽  
Peter N. Ruygrok

1973 ◽  
Vol 15 (3) ◽  
pp. 249-255 ◽  
Author(s):  
Richard P. Anderson ◽  
Lawrence I. Bonchek ◽  
James A. Wood ◽  
Richard P. Chapman ◽  
Albert Starr

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Charbel Abi Khalil ◽  
Barbara Ignatiuk ◽  
Guliz Erdem ◽  
Hiam Chemaitelly ◽  
Fabio Barilli ◽  
...  

AbstractTranscatheter aortic valve replacement (TAVR) has shown to reduce mortality compared to surgical aortic valve replacement (sAVR). However, it is unknown which procedure is associated with better post-procedural valvular function. We conducted a meta-analysis of randomized clinical trials that compared TAVR to sAVR for at least 2 years. The primary outcome was post-procedural patient-prosthesis-mismatch (PPM). Secondary outcomes were post-procedural and 2-year: effective orifice area (EOA), paravalvular gradient (PVG) and moderate/severe paravalvular leak (PVL). We identified 6 trials with a total of 7022 participants with severe aortic stenosis. TAVR was associated with 37% (95% CI [0.51–0.78) mean RR reduction of post-procedural PPM, a decrease that was not affected by the surgical risk at inclusion, neither by the transcatheter heart valve system. Postprocedural changes in gradient and EOA were also in favor of TAVR as there was a pooled mean difference decrease of 0.56 (95% CI [0.73–0.38]) in gradient and an increase of 0.47 (95% CI [0.38–0.56]) in EOA. Additionally, self-expandable valves were associated with a higher decrease in gradient than balloon ones (beta = 0.38; 95% CI [0.12–0.64]). However, TAVR was associated with a higher risk of moderate/severe PVL (pooled RR: 9.54, 95% CI [5.53–16.46]). All results were sustainable at 2 years.


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