Enantioseparation of tetrahydropalmatine and Tröger's base by molecularly imprinted monolith in capillary electrochromatography

2007 ◽  
Vol 70 (1) ◽  
pp. 71-76 ◽  
Author(s):  
Junjie Ou ◽  
Jing Dong ◽  
Tuijun Tian ◽  
Jiwei Hu ◽  
Mingliang Ye ◽  
...  
Keyword(s):  
Capillary Electrochromatography ◽  
Molecularly Imprinted ◽  
Troger's Base ◽  
Molecularly Imprinted Monolith

scholarly journals Determination of sulfamerazine in aquatic products by molecularly imprinted capillary electrochromatography

2019 ◽  
Vol 6 (6) ◽  
pp. 190119 ◽  
Author(s):  
Shili Qin ◽  
Fenglong Jin ◽  
Lidi Gao ◽  
Liqiang Su ◽  
Yingjie Li ◽  
...  
Keyword(s):  
Capillary Electrochromatography ◽  
Limit Of Detection ◽  
Single Step ◽  
Column Temperature ◽  
Molecularly Imprinted ◽  
Molar Ratios ◽  
Aquatic Products ◽  
Molecularly Imprinted Monolith ◽  
Pre Treatment ◽  
Molecularly Imprinted Technology

A molecularly imprinted monolith was prepared and evaluated for the special selective separation of sulfamerazine (SMR) by capillary electrochromatography (CEC). The single-step in situ polymerization method was applied through thermally immobilized vinyl groups of itaconic acid and a derivatization capillary column using SMR as the template. The monolith with optimal selectivity and permeability was performed at 45°C for 7 h according to the molar ratios of 1 : 4 : 10 (template/functional monomer/cross-linker). Under the optimized separation conditions of 75% acetonitrile in 20 mM phosphate buffer with pH 5.0, 15 kV applied voltage and 20°C column temperature, the imprinted monolith showed strong recognition ability for SMR and high column performance. Finally, the molecularly imprinted monolith coupled with the CEC method was successfully developed for the quantification of SMR in aquatic products, which was properly validated by a good linear relationship, recoveries and limit of detection. The coupling technique of the molecularly imprinted technology and CEC achieved pre-treatment enrichment and separation analysis in only one miniaturized chromatographic column.

Microwave-Assisted Preparation of Molecularly Imprinted Monolith Combining Imidazolium Ionic Liquid and POSS for Enhanced Extraction of Baicalin-Like Compounds in Scutellaria Baicalensis by means of In-Capillary SPME Followed by on-line LC and off-line LC-MS/MS

2021 ◽  
Author(s):  
Xiaohan Zhang ◽  
Le Gao ◽  
Liying Niu ◽  
Xiaodong Bi
Keyword(s):  
Ionic Liquid ◽  
Molecularly Imprinted Polymers ◽  
Scutellaria Baicalensis ◽  
Synthetic Methods ◽  
Imidazolium Ionic Liquid ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Microwave Assisted ◽  
On Line ◽  
Molecularly Imprinted Monolith

Molecularly imprinted polymers (MIPs) possess target-customized and range-adjustable selectivity, and hence have been attracting increasing efforts to develop new synthetic methods and new forms of applications. By wisely choosing functional...

Application of Response Surface Methodology to Synthesize Appropriate Molecularly Imprinted Polymer for Diazinon

2014 ◽  
Vol 605 ◽  
pp. 67-70 ◽  
Author(s):  
Mohsen Rahiminezhad ◽  
Seyed Jamaleddin Shahtaheri ◽  
Mohammad Reza Ganjali ◽  
Abbas Rahimi Rahimi Forushani
Keyword(s):  
Molecular Imprinting ◽  
Molecularly Imprinted Polymer ◽  
Binding Sites ◽  
Capillary Electrochromatography ◽  
Template Molecule ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Functional Monomers ◽  
Molecular Imprinting Technology ◽  
Cross Linker

Molecular imprinting technology has become an interesting research area to the preparation of specific sorbent material for environmental and occupational sample preparation techniques (1). In the molecular imprinting technology, specific binding sites have been formed in polymeric matrix, which often have an affinity and selectivity similar to antibody-antigen systems (2). In molecular imprinted technology, functional monomers are arranged in a complementary configuration around a template molecule, then, cross-linker and solvent are also added and the mixture is treated to give a porous material containing nono-sized binding sites. After extraction of the template molecule by washing, vacant imprinted sites will be left in polymer, which are available for rebinding of the template or its structural analogue (3). The stability, convention of preparation and low cost of these materials make them particularly attractive (4). These synthetic materials have been used for capillary electrochromatography (5), chromatography columns (6), sensors (7), and catalyze system (8). Depending on the molecular imprinting approach, different experimental variables such as the type and amounts of functional monomers, porogenic solvent, initiator, monomer to cross-linker ratio, temperature, and etc may alter the properties of the final polymeric materials. In this work, chemometric approach based on Central Composite Design (CCD) was used to design the experiments as well as to find the optimum conditions for preparing appropriate diazinon molecularly imprinted polymer.

Preparation of a POSS-hybridized molecularly imprinted monolith for the analysis of baicalin and its analogues in a microwave-assisted extract from Scutellaria baicalensis by means of on-line SPME-HPLC and off-line LC-MS/MS

2019 ◽  
Vol 11 (17) ◽  
pp. 2351-2361 ◽  
Author(s):  
Xiaodong Bi ◽  
Wei Tian ◽  
Xiang Wang ◽  
Wenli Cao ◽  
Le Gao ◽  
...  
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Scutellaria Baicalensis ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Microwave Assisted ◽  
On Line ◽  
Molecularly Imprinted Monolith

Molecularly imprinted polymers (MIPs) have been attracting increasing attention and used in various applications.

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