The Potential Value of PHH-3 Mitotic Index Determined by Digital Image Analysis in the Assessment of Pancreatic Endocrine Tumors in Fine Needle Aspiration Cytology specimens

2012 ◽  
Vol 1 (1) ◽  
pp. S119
Author(s):  
Rossitza Draganova-Tacheva ◽  
Marluce Bibbo ◽  
Ruth Birbe ◽  
Charalambos Solomides
Keyword(s):  
Image Analysis ◽  
Fine Needle Aspiration ◽  
Digital Image Analysis ◽  
Needle Aspiration ◽  
Endocrine Tumors ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Potential Value ◽  
Pancreatic Endocrine Tumors ◽  
Needle Aspiration Cytology

Fine-needle aspiration cytology in pancreatic endocrine tumors

1987 ◽  
Vol 3 (1) ◽  
pp. 35-40 ◽  
Author(s):  
Nour Sneige ◽  
Nelson G. Ordonez ◽  
Susan Veanattukalathil ◽  
Naguib A. Samaan
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Endocrine Tumors ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Pancreatic Endocrine Tumors ◽  
Needle Aspiration Cytology

scholarly journals Liver metastases of pancreatic acinar cell carcinoma with marked nuclear atypia and pleomorphism diagnosed by EUS FNA cytology : A case report with emphasis on FNA cytological findings

CytoJournal ◽  
2006 ◽  
Vol 3 ◽  
pp. 29 ◽  
Author(s):  
Hong Q Peng ◽  
Peter Darwin ◽  
John C Papadimitriou ◽  
Cinthia B Drachenberg
Keyword(s):  
Cell Carcinoma ◽  
Acinar Cell ◽  
Fine Needle Aspiration ◽  
Acinar Cell Carcinoma ◽  
Needle Aspiration ◽  
Pancreatic Acinar Cell ◽  
Endocrine Tumors ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Background: Acinar cell carcinoma of the pancreas is a rare neoplasm. Although this tumor has been well characterized histologically, the morphological patterns in Fine Needle Aspiration Cytology have not been well defined. Unlike ductal adenocarcinomas, endocrine tumors, and solid pseudopapillary tumors of the pancreas with their characteristic FNA cytological features, acinar cell carcinomas pose a particular diagnostic challenge by sharing many cytomorphologic features with endocrine tumors of the pancreas. Case presentation: A 37-year-old man presented with lower chest and left upper quadrant abdominal pain. Computed tomography revealed a 7.8 x 7.3 cm irregular, partially cystic mass in the body and tail of the pancreas, and two lesions in the liver compatible with metastases. Subsequently, the patient underwent endoscopic ultrasound-guided fine needle aspiration on one of the two metastatic liver masses. Conclusion: We describe a case of pancreatic acinar cell carcinoma with unusual cytomorphologic features mimicking an endocrine tumor of pancreas, encountered in endoscopic ultrasound-guided fine needle aspiration of a metastatic liver mass and discuss the diagnostic approach for this unusual pancreatic tumor in fine needle aspiration cytology.

Role of fine needle aspiration cytology in the preoperative diagnosis of malignancy in parotid and submandibular gland neoplasm

2014 ◽  
Vol 19 (2) ◽  
pp. 110-118
Author(s):  
Mohammad Amzad Hossain ◽  
Md Zahedul Alam ◽  
Md Rojibul Haque ◽  
Md Nazmul Haque ◽  
KM Nurul Alam ◽  
...  
Keyword(s):  
Submandibular Gland ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
False Negative ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Medical College ◽  
Preoperative Diagnostic ◽  
Needle Aspiration Cytology

Objective: To evaluate the role of Fine Needle Aspiration Cytology in the preoperative diagnosis of malignancy in parotid and submandibular gland neoplasm. Methods: This cross sectional study on 50 cases was conducted in the Department of Otolaryngology and Head-Neck Surgery of Sir Salimullah Medical College Mitford Hospital and Dhaka Medical College Hospital from January’2009 to June 2010. Results: Fine needle aspiration cytology findings of our all 50 cases were compared with postoperative histopathological reports. Out of the 50 cases, in 36(72%) cases of benign neoplasm and 7(14%) cases of malignant neoplasm, pre-operative FNAC findings and post operative histopathological findings were same. In 7 cases, FNAC and post operative histopathological findings did not matched. These were 2 (4%) false positive and 5 (10%) false negative result.In our study sensitivity of FNAC for reporting malignancy was 58.33%, specificity to rule out malignancy was 94.73% and overall accuracy in detecting malignant tumour was 86%. Positive predictive value and negative value were 77.77% and 87.80% respectively. It can be concluded that fine needle aspiration cytology is a safe, cheap and useful preoperative diagnostic tool in the diagnosis of malignancy in parotid and submandibular gland, but as fine needle aspiration cytology partly depends on operator skill, it may give false negative and false positive result. Conclusion: FNAC is a useful preoperative diagnostic tool for malignant parotid and submandibular glands with high specificity and sensitivity. DOI: http://dx.doi.org/10.3329/bjo.v19i2.17634 Bangladesh J Otorhinolaryngol 2013; 19(2): 110-118

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