Reducing Recurrent Hospitalizations in a Resident With Short Gut Syndrome

2021 ◽  
Vol 22 (3) ◽  
pp. B8
Author(s):  
Charitha Tokur-Sridhar ◽  
C. Tokur-Sridhar ◽  
J. Sondgeroth ◽  
L. Kobeissi ◽  
R. Shropshire ◽  
...  
Keyword(s):  
Short Gut Syndrome

scholarly journals Can an amino acid mixture alleviate gastrointestinal symptoms in neuroendocrine tumor patients?

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Aman Chauhan ◽  
Satya Das ◽  
Rachel Miller ◽  
Laura Luque ◽  
Samuel N. Cheuvront ◽  
...  
Keyword(s):  
Amino Acid ◽  
Neuroendocrine Tumor ◽  
Gastrointestinal Symptoms ◽  
Retrospective Chart Review ◽  
Final Analysis ◽  
Acid Mixture ◽  
Tumor Patients ◽  
Short Gut Syndrome ◽  
Oral Rehydration ◽  
The Mean

Abstract Background Neuroendocrine tumors, although relatively rare in incidence, are now the second most prevalent gastrointestinal neoplasm owing to indolent disease biology. A small but significant sub-group of neuroendocrine tumor patients suffer from diarrhea. This is usually secondary to carcinoid syndrome but can also be a result of short gut syndrome, bile acid excess or iatrogenic etiologies. Recently, an amino acid based oral rehydration solution (enterade® Advanced Oncology Formula) was found to have anti-diarrheal properties in preclinical models. Methods A retrospective chart review of all NET patients treated with enterade® AO was performed after IRB approval. Results Ninety-eight NET patients who had received enterade® AO at our clinic from May 2017 through June 2019 were included. Patients (N = 49 of 98) with follow up data on bowel movements (BMs) were included for final analysis. Eighty-four percent of patients (41/49) had fewer BMs after taking enterade® AO and 66% (27/41) reported more than 50% reduction in BM frequency. The mean number of daily BMs was 6.6 (range, 3–20) at baseline before initiation of therapy, while the mean number of BMs at 1 week time point post enterade® AO was 2.9 (range, 0–11). Conclusions Our retrospective observations are encouraging and support prospective validation with appropriate controls in NET patients. This is first published report of the potential anti-diarrheal activity of enterade® AO in NET patients.

Complications: Short Gut Syndrome

2020 ◽  
pp. 699-709
Author(s):  
Ramzi M. Helewa ◽  
Robin P. Boushey
Keyword(s):  
Short Gut Syndrome

Induction of Short Gut Syndrome and Transplantation in a Porcine Model

2006 ◽  
Vol 38 (6) ◽  
pp. 1855-1856 ◽  
Author(s):  
J.C. Llanos ◽  
A. Bakonyi Neto ◽  
M.M. Lerco ◽  
R.M.O. Clark ◽  
A. Polachini do Valle ◽  
...  
Keyword(s):  
Porcine Model ◽  
Short Gut Syndrome

Intestinal transplants show impaired regulation of transit in short gut syndrome

1998 ◽  
Vol 114 ◽  
pp. A1398
Author(s):  
C.P. Johnson ◽  
S.K. Sarna ◽  
Y.R. Zhu ◽  
G. Telford ◽  
A.M. Roza ◽  
...  
Keyword(s):  
Short Gut Syndrome

Intestinal Transplantation in Pediatric Patients

2002 ◽  
Vol 12 (2) ◽  
pp. 97-115 ◽  
Author(s):  
Beverly Kosmach Park
Keyword(s):  
Medical Management ◽  
Management Strategies ◽  
Intestinal Failure ◽  
Intestinal Transplantation ◽  
Term Survival ◽  
Short Gut Syndrome ◽  
Assessment And Treatment ◽  
Life Threatening ◽  
End Stage ◽  
Intestine Transplantation

Intestine transplantation has evolved into a feasible alternative for children with permanent intestinal failure and life-threatening complications related to total parenteral nutrition. Although the first transplantations were done nearly 40 years ago, long-term survival has only been achieved in the last decade. Nearly 700 intestinal transplantations have been performed internationally since 1985, with an overall patient survival of greater than 50%. Improvements in patient selection, medical management, and assessment and treatment for rejection and infection have contributed to the increased survival. This article will discuss current results and medical management strategies for this innovative type of transplantation for children with end-stage short gut syndrome.

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