Association Between Sleep Disturbances and Frailty: Evidence From a Population-Based Study

Author(s):  
Vassilis Balomenos ◽  
Eva Ntanasi ◽  
Costas A. Anastasiou ◽  
Socrates Charisis ◽  
Georgios Velonakis ◽  
...  
2010 ◽  
Vol 169 (8) ◽  
pp. 1009-1015 ◽  
Author(s):  
Raphaële Reine Lydie van Litsenburg ◽  
Ruth C. Waumans ◽  
Gerrit van den Berg ◽  
Reinoud J. B. J. Gemke

BMC Medicine ◽  
2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Shireen Sindi ◽  
Laura Monica Pérez ◽  
Davide L. Vetrano ◽  
Federico Triolo ◽  
Ingemar Kåreholt ◽  
...  

Abstract Background Sleep disturbances are prevalent among older adults and are associated with various individual diseases. The aim of this study was to investigate whether sleep disturbances are associated with the speed of multimorbidity development among older adults. Methods Data were gathered from the Swedish National study of Aging and Care in Kungsholmen (SNAC-K), an ongoing population-based study of subjects aged 60+ (N = 3363). The study included a subsample (n = 1189) without multimorbidity at baseline (< 2 chronic diseases). Baseline sleep disturbances were derived from the Comprehensive Psychiatric Rating Scale and categorized as none, mild, and moderate–severe. The number of chronic conditions throughout the 9-year follow-up was obtained from clinical examinations. Linear mixed models were used to study the association between sleep disturbances and the speed of chronic disease accumulation, adjusting for sex, age, education, physical activity, smoking, alcohol consumption, depression, pain, and psychotropic drug use. We repeated the analyses including only cardiovascular, neuropsychiatric, or musculoskeletal diseases as the outcome. Results Moderate–severe sleep disturbances were associated with a higher speed of chronic disease accumulation (ß/year = 0.142, p = 0.008), regardless of potential confounders. Significant positive associations were also found between moderate–severe sleep disturbances and neuropsychiatric (ß/year = 0.041, p = 0.016) and musculoskeletal (ß/year = 0.038, p = 0.025) disease accumulation, but not with cardiovascular diseases. Results remained stable when participants with baseline dementia, cognitive impairment, or depression were excluded. Conclusion The finding that sleep disturbances are associated with faster chronic disease accumulation points towards the importance of early detection and treatment of sleep disturbances as a possible strategy to reduce chronic multimorbidity among older adults.


Brain ◽  
2019 ◽  
Vol 142 (7) ◽  
pp. 2013-2022 ◽  
Author(s):  
Thom S Lysen ◽  
Sirwan K L Darweesh ◽  
M Kamran Ikram ◽  
Annemarie I Luik ◽  
M Arfan Ikram

While specific sleep disorders are known to precede Parkinson’s disease, it remains unclear how sleep disturbances in the general population affect risk. Lysen et al. report that poor sleep quality and short sleep duration, and their deterioration over time, are associated with increased risk of parkinsonism, including Parkinson’s disease.


2004 ◽  
Vol 79 (12) ◽  
pp. 1501-1506 ◽  
Author(s):  
Santhi Swaroop Vege ◽  
G. Richard Locke ◽  
Amy L. Weaver ◽  
Sara A. Farmer ◽  
L. Joseph Melton ◽  
...  

2015 ◽  
Vol 32 (9) ◽  
pp. 684-692 ◽  
Author(s):  
Annemarie I. Luik ◽  
Lisette A. Zuurbier ◽  
Neşe Direk ◽  
Albert Hofman ◽  
Eus J.W. Van Someren ◽  
...  

Sleep Health ◽  
2020 ◽  
Author(s):  
Gustavo Velasquez-Melendez ◽  
Flávia Cristina Drumond Andrade ◽  
Alexandra Dias Moreira ◽  
Rosalba Hernandez ◽  
Maria Alice Souza Vieira ◽  
...  

Author(s):  
Alexander Gontard ◽  
Hannah Mattheus ◽  
Jana Friese‐Jaworsky ◽  
Anna‐Michaela Moritz ◽  
Sigrid Thome‐Granz ◽  
...  

2015 ◽  
Vol 135 (1) ◽  
pp. 56-66 ◽  
Author(s):  
Jonathan I. Silverberg ◽  
Nitin K. Garg ◽  
Amy S. Paller ◽  
Anna B. Fishbein ◽  
Phyllis C. Zee

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