The Effects of Mold-Fermented Cheese on Brain-Derived Neurotrophic Factor in Community-Dwelling Older Japanese Women With Mild Cognitive Impairment: A Randomized, Controlled, Crossover Trial

2019 ◽  
Vol 20 (12) ◽  
pp. 1509-1514.e2 ◽  
Author(s):  
Takao Suzuki ◽  
Narumi Kojima ◽  
Yosuke Osuka ◽  
Yuka Tokui ◽  
Satoshi Takasugi ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Neurotrophic Factor ◽  
Crossover Trial ◽  
Brain Derived Neurotrophic Factor ◽  
Japanese Women ◽  
Community Dwelling ◽  
Randomized Controlled

Effect of Cognitive Training on the Expression of Brain-Derived Neurotrophic Factor in Lymphocytes of Mild Cognitive Impairment Patients

2014 ◽  
Vol 17 (2) ◽  
pp. 235-238 ◽  
Author(s):  
Tiziana Casoli ◽  
Cinzia Giuli ◽  
Marta Balietti ◽  
Belinda Giorgetti ◽  
Moreno Solazzi ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Training ◽  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor

Is Blood Brain-Derived Neurotrophic Factor a Useful Biomarker to Monitor Mild Cognitive Impairment Patients?

2020 ◽  
Vol 23 (5) ◽  
pp. 411-419
Author(s):  
Marta Balietti ◽  
Cinzia Giuli ◽  
Tiziana Casoli ◽  
Paolo Fabbietti ◽  
Fiorenzo Conti
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Blood Brain

Effects of combined physical and cognitive training on fall prevention and risk reduction in older persons with mild cognitive impairment: a randomized controlled study

2020 ◽  
Vol 34 (6) ◽  
pp. 773-782 ◽  
Author(s):  
Donald S Lipardo ◽  
William WN Tsang
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Training ◽  
Older Persons ◽  
Dynamic Balance ◽  
Community Dwelling ◽  
Controlled Study ◽  
Fall Rate ◽  
Randomized Controlled ◽  
Significant Difference

Objective: The aim of this study is to investigate the effects of combined physical and cognitive training on fall rate and risks of falling in older adults with mild cognitive impairment. Design: The design of this study was an assessor-blinded, randomized controlled trial. Setting: The setting for this study is the community from Manila, Philippines. Subjects: In total, 92 community-dwelling older persons with mild cognitive impairment (aged 60–83) were randomly allocated to three intervention groups and one waitlist control group. Interventions: The physical training, cognitive training, and combined physical and cognitive training intervention programs were delivered for 60 to 90 minutes, one to three times per week for 12 weeks with six-month follow-up. Main measures: Participants were assessed at baseline, 12 weeks after baseline, and 36 weeks after baseline for fall incidence, overall fall risk, dynamic balance, walking speed, and lower limb strength. Results: No significant difference was observed across time and groups on fall incidence rate at 12 weeks ( P = 0.152) and at 36 weeks ( P = 0.954). The groups did not statistically differ in other measures except for a significant improvement in dynamic balance based on Timed Up and Go Test in the combined physical and cognitive training group (9.0 seconds with P = 0.001) and in the cognitive training alone group (8.6 seconds with P = 0.012) compared to waitlist group (11.1 seconds) at 36 weeks. Conclusion: There was no significant difference among groups on fall rate and risks of falling post-intervention. Dynamic balance was improved with combined physical and cognitive training and cognitive training alone. Further research with a larger sample size is needed to establish whether or not the interventions are effective.

Effect of brain-derived neurotrophic factor Val66Met polymorphism and serum levels on the progression of mild cognitive impairment

2010 ◽  
Vol 11 (6) ◽  
pp. 774-780 ◽  
Author(s):  
Orestes Vicente Forlenza ◽  
Breno Satler Diniz ◽  
Antonio Lucio Teixeira ◽  
Elida Benquique Ojopi ◽  
Leda Leme Talib ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Neurotrophic Factor ◽  
Serum Levels ◽  
Brain Derived Neurotrophic Factor ◽  
Val66met Polymorphism

P3-002: Brain-derived neurotrophic factor serum level is reduced in mild cognitive impairment and Alzheimer's disease

2009 ◽  
Vol 5 (4S_Part_11) ◽  
pp. P341-P341
Author(s):  
Breno S. Diniz ◽  
V. Forlenza Orestes ◽  
Leda L. Talib ◽  
Vaneesa Amaral ◽  
Elida Ojopi ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Serum Level ◽  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor
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