scholarly journals Determinants of Potentially Inappropriate Medication Use in Long-Term and Acute Care Settings: A Systematic Review

2017 ◽  
Vol 18 (9) ◽  
pp. 806.e1-806.e17 ◽  
Author(s):  
Stephanie K. Nothelle ◽  
Ritu Sharma ◽  
Allison H. Oakes ◽  
Madeline Jackson ◽  
Jodi B. Segal
Keyword(s):  
Systematic Review ◽  
Acute Care ◽  
Inappropriate Medication ◽  
Medication Use ◽  
Potentially Inappropriate Medication ◽  
Inappropriate Medication Use ◽  
Acute Care Settings

Polypharmacy and Potentially Inappropriate Medication Use Among Long Term Care Residents on Hospice Care

2011 ◽  
Vol 12 (3) ◽  
pp. B20
Author(s):  
Gina Gerardine S. Fernandez ◽  
Gina Gerardine S. Fernandez ◽  
Amy Ehrlich ◽  
Claudene George ◽  
Rubina Malik ◽  
...  
Keyword(s):  
Long Term Care ◽  
Hospice Care ◽  
Inappropriate Medication ◽  
Medication Use ◽  
Potentially Inappropriate Medication ◽  
Term Care ◽  
Inappropriate Medication Use

scholarly journals Epidemiology of potentially inappropriate medication use in elderly patients in Japanese acute care hospitals

2011 ◽  
Vol 20 (4) ◽  
pp. 386-392 ◽  
Author(s):  
Mio Sakuma ◽  
Takeshi Morimoto ◽  
Kunihiko Matsui ◽  
Susumu Seki ◽  
Nobuo Kuramoto ◽  
...  
Keyword(s):  
Elderly Patients ◽  
Acute Care ◽  
Inappropriate Medication ◽  
Medication Use ◽  
Acute Care Hospitals ◽  
Potentially Inappropriate Medication ◽  
Inappropriate Medication Use

scholarly journals Use of potentially inappropriate medications among ambulatory home-dwelling elderly patients with dementia: A review of the literature

2017 ◽  
Vol 150 (3) ◽  
pp. 169-183 ◽  
Author(s):  
Tejal Patel ◽  
Karen Slonim ◽  
Linda Lee
Keyword(s):  
Older Adults ◽  
Cognitive Impairment ◽  
Adverse Events ◽  
Inappropriate Medication ◽  
Medication Use ◽  
Adverse Outcomes ◽  
Potentially Inappropriate Medication ◽  
Potentially Inappropriate Medications ◽  
Inappropriate Medication Use ◽  
Inappropriate Medications

Background: Older adults with dementia are at high risk for drug-related adverse outcomes. While much is known about potentially inappropriate medication use in older adults, its prevalence and characteristics among those with dementia are not as well elucidated. We conducted a literature review to examine the prevalence of potentially inappropriate medication use among home-dwelling older adults with dementia. Our secondary aim was to determine the most frequently implicated medications and factors associated with potentially inappropriate medication use. Methods: MEDLINE, EMBASE, CINAHL, and International Pharmaceutical Abstracts were searched between 1946 and 2014 for articles that referenced potentially inappropriate medication use and types of dementia. One reviewer screened all titles and abstracts from the initial search and full-text articles after the initial screen for eligibility, then 2 reviewers independently abstracted data from included studies. Results: Searches yielded 81 articles, of which 7 met inclusion criteria. Prevalence of potentially inappropriate medication use varied from 15% to 46.8%. No single drug or drug class was reported consistently across all studies as the most frequent potentially inappropriate medication, but anticholinergics and benzodiazepines, drugs that affect cognition, were among the most common medications or pharmacological classes listed. Discussion: Older adults with dementia may be particularly vulnerable to potentially inappropriate medications because of cognitive impairment from their condition and the greater likelihood of experiencing adverse events from medications. Given this population’s greater susceptibility to adverse events, more intense medication and patient monitoring may be warranted, especially among those taking anticholinergics and benzodiazepines, as these drugs can contribute to cognitive impairment.

Polypharmacy and Potentially Inappropriate Medication Use in Older Blacks with Diabetes Mellitus Presenting to the Emergency Department

2021 ◽  
pp. 089826432110455
Author(s):  
Ginah Nightingale ◽  
Emily M. Scopelliti ◽  
Robin Casten ◽  
Monica Woloshin ◽  
Shu Xiao ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Emergency Department ◽  
Controlled Trial ◽  
Inappropriate Medication ◽  
Medication Use ◽  
Potentially Inappropriate Medication ◽  
Cross Sectional ◽  
Randomized Controlled ◽  
Inappropriate Medication Use ◽  
Sectional Analysis

Background: Medication-related problems in older Blacks with diabetes mellitus (DM) are not well established. Objectives: To describe the frequency of medication-related problems in older Blacks with DM presenting to the emergency department (ED). Methods: The study was a cross-sectional analysis of baseline data from a randomized controlled trial evaluating Blacks aged ≥60 years of age presenting to the ED. Polypharmacy, potentially inappropriate medication (PIM) use, and anticholinergic score were evaluated. Results: Of 168 patients (median age = 68, range 60–92), most ( n = 164, 98%) were taking ≥5 medications, and 67 (39.9%) were taking a PIM. A majority ( n = 124, 74%) were taking a medication with an anticholinergic score ≥1. Number of medications was correlated with number of PIMs ( r = .22, p = .004) and anticholinergic score ( r = .50, p < .001). Conclusion: Polypharmacy and PIM use was common in older Blacks with DM.

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