Adverse Effects of Anticoagulation and Antiplatelet Therapies in a Frail Nursing Home Patient

2016 ◽  
Vol 17 (3) ◽  
pp. B3
Author(s):  
Scott Hanson ◽  
Scott Hanson ◽  
Allysa Houfek ◽  
Erin Nelson ◽  
Phoung Nguyen ◽  
...  
Keyword(s):  
Nursing Home ◽  
Adverse Effects ◽  
Nursing Home Patient

scholarly journals Neutralizing Anti-SARS-CoV-2 Antibody Titer and Reported Adverse Effects, in a Sample of Italian Nursing Home Personnel after Two Doses of the BNT162b2 Vaccine Administered Four Weeks Apart

Vaccines ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 652
Author(s):  
Alberto Modenese ◽  
Stefania Paduano ◽  
Annalisa Bargellini ◽  
Rossana Bellucci ◽  
Simona Marchetti ◽  
...  
Keyword(s):  
Nursing Home ◽  
Adverse Effects ◽  
Antibody Titer ◽  
Healthcare Workers ◽  
Vaccination Campaign ◽  
Northern Italy ◽  
High Antibody ◽  
Protective Level ◽  
High Antibody Titer ◽  
Main Factors

Background: The immunization of healthcare workers (HCWs) plays a recognized key role in prevention in the COVID-19 pandemic: in Italy, the vaccination campaign began at the end of December 2020. A better knowledge of the on-field immune response in HCWs, of adverse effects and of the main factors involved is fundamental. Methods: We performed a study on workers at a nursing home in Northern Italy, vaccinated in January–February 2021 with two doses of the BNT162b2 vaccine four weeks apart, instead of the three weeks provided for in the original manufacturer protocol. One month after the second dose, the serological titer of IgG-neutralizing anti-RBD antibodies of the subunit S1 of the spike protein of SARS-CoV-2 was determined. The socio-demographic and clinical characteristics of the subjects and adverse effects of vaccination were collected by questionnaire. Results: In all of the workers, high antibody titer, ranging between 20 and 760 times the minimum protective level were observed. Titers were significantly higher in subjects with a previous COVID-19 diagnosis. Adverse effects after the vaccine were more frequent after the second dose, but no severe adverse effects were observed. Conclusions: The two doses of the BNT162b2 vaccine, even if administered four weeks apart, induced high titers of anti-SARS-CoV-2 neutralizing IgG in all the operators included in the study.

Adverse effects of pneumonia on physical functioning in nursing home residents: Results from the INCUR study

2016 ◽  
Vol 65 ◽  
pp. 116-121 ◽  
Author(s):  
Emiel O. Hoogendijk ◽  
Natalia Del Campo ◽  
Yves Rolland ◽  
Laurent Demougeot ◽  
Stéphane Gérard ◽  
...  
Keyword(s):  
Nursing Home ◽  
Adverse Effects ◽  
Physical Functioning ◽  
Nursing Home Residents

Psychoactive Drug Misuse in Long-Term Care: Some Contributing Factors

1988 ◽  
Vol 1 (3) ◽  
pp. 189-194 ◽  
Author(s):  
David S. Sherman
Keyword(s):  
Nursing Home ◽  
Adverse Effects ◽  
Nursing Home Residents ◽  
Psychoactive Drug ◽  
Prescribing Patterns ◽  
Drug Misuse ◽  
Psychoactive Drugs ◽  
Contributing Factors ◽  
Term Care ◽  
Home Setting

Surveys have identified inappropriate psychoactive drug prescribing patterns as a major problem in the care of nursing home residents. Residents without a documented history of mental illness often receive drugs intended to treat psychiatric problems. One of the greatest areas of misuse of these drugs is in the treatment of agitation in elderly demented residents. For example, although this purpose is likely the most common reason antipsychotic drugs are used in the nursing home setting, no well designed study has yet demonstrated that these agents are effective for this problem. Elderly individuals are particularly sensitive to the adverse effects of psychoactive drugs. Due to the gradual or insidious onset of some adverse effects, psychoactive drug toxicity may often be underestimated. The most serious example of a clinically underrecognized adverse effect of psychoactive drugs is tardive dyskinesia. Misinterpretation of certain nursing home residents' behaviors may lead to medication with tranquilizing drugs when other approaches may be safer and more effective. Excessive use of psychoactive drugs is not only physically harmful, but also encourages an apathetic attitude toward implementation of more humane ways of dealing with behaviorally disturbed nursing home residents.

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