scholarly journals Longitudinal associations between specific symptoms of depression: Network analysis in a prospective cohort study

2021 ◽  
Vol 278 ◽  
pp. 99-106
Author(s):  
Kateryna Savelieva ◽  
Kaisla Komulainen ◽  
Marko Elovainio ◽  
Markus Jokela
Keyword(s):  
Cohort Study ◽  
Network Analysis ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Symptoms Of Depression ◽  
Longitudinal Associations ◽  
Specific Symptoms

scholarly journals Diversity in citations to a single study: A citation context network analysis of how evidence from a prospective cohort study was cited

2021 ◽  
pp. 1-30
Author(s):  
Rhodri Ivor Leng
Keyword(s):  
Cohort Study ◽  
Heart Disease ◽  
Network Analysis ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Empirical Finding ◽  
Coffee Consumption ◽  
Consensus Conference ◽  
Cluster Membership ◽  
Citation Context

Abstract Between its origin in the 1950s and its endorsement by a consensus conference in 1984, the diet–heart hypothesis was the subject of intense controversy. Paul et al. (1963) is a highly cited prospective cohort study that reported findings inconvenient for this hypothesis, reporting no association between diet and heart disease; however, many other findings were also reported. By citation context and network analysis of 343 citing papers, I show how Paul et al. was cited in the 20 years after its publication. Generally, different findings were cited by different communities focusing on different risk factors; these communities were established by either research foci title terms or via cluster membership as established via modularity maximization. The most frequently cited findings were the significant associations between heart disease and serum cholesterol (n = 85), blood pressure (n = 57), and coffee consumption (n = 54). The lack of association between diet and heart disease was cited in just 41 papers. Yet, no single empirical finding was referred to in more than 25% of the citing papers. This raises questions about the value of inferring impact from citation counts alone and raises problems for studies using such counts to measure citation bias.

scholarly journals Symptoms of Depression in Survivors of Severe Sepsis: A Prospective Cohort Study of Older Americans

2013 ◽  
Vol 21 (9) ◽  
pp. 887-897 ◽  
Author(s):  
Dimitry S. Davydow ◽  
Catherine L. Hough ◽  
Kenneth M. Langa ◽  
Theodore J. Iwashyna
Keyword(s):  
Severe Sepsis ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Older Americans ◽  
Symptoms Of Depression

scholarly journals Abdominal symptoms and cancer in the abdomen: prospective cohort study in European primary care

2018 ◽  
Vol 68 (670) ◽  
pp. e301-e310 ◽  
Author(s):  
Knut Holtedahl ◽  
Peter Hjertholm ◽  
Lars Borgquist ◽  
Gé A Donker ◽  
Frank Buntinx ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Rectal Bleeding ◽  
Prospective Cohort ◽  
High Specificity ◽  
Predictive Values ◽  
Abdominal Symptoms ◽  
Diagnosis Of Cancer ◽  
Irregular Bleeding ◽  
Specific Symptoms

BackgroundDifferent abdominal symptoms may signal cancer, but their role is unclear.AimTo examine associations between abdominal symptoms and subsequent cancer diagnosed in the abdominal region.Design and settingProspective cohort study comprising 493 GPs from surgeries in Norway, Denmark, Sweden, Scotland, Belgium, and the Netherlands.MethodOver a 10-day period, the GPs recorded consecutive consultations and noted: patients who presented with abdominal symptoms pre-specified on the registration form; additional data on non-specific symptoms; and features of the consultation. Eight months later, data on all cancer diagnoses among all study patients in the participating general practices were requested from the GPs.ResultsConsultations with 61 802 patients were recorded and abdominal symptoms were documented in 6264 (10.1%) patients. Malignancy, both abdominal and non-abdominal, was subsequently diagnosed in 511 patients (0.8%). Among patients with a new cancer in the abdomen (n = 251), 175 (69.7%) were diagnosed within 180 days after consultation. In a multivariate model, the highest sex- and age-adjusted hazard ratio (HR) was for the single symptom of rectal bleeding (HR 19.1, 95% confidence interval = 8.7 to 41.7). Positive predictive values of >3% were found for macroscopic haematuria, rectal bleeding, and involuntary weight loss, with variations according to age and sex. The three symptoms relating to irregular bleeding had particularly high specificity in terms of colorectal, uterine, and bladder cancer.ConclusionsA patient with undiagnosed cancer may present with symptoms or no symptoms. Irregular bleeding must always be explained. Abdominal pain occurs with all types of abdominal cancer and several symptoms may signal colorectal cancer. The findings are important as they influence how GPs think and act, and how they can contribute to an earlier diagnosis of cancer.

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