Long-term treatment with supraphysiologic doses of levothyroxine in treatment-refractory mood disorders – A prospective study of cardiovascular tolerability

2018 ◽  
Vol 238 ◽  
pp. 213-217 ◽  
Author(s):  
Maximilian Pilhatsch ◽  
Anne Berghöfer ◽  
René Mayer-Pelinski ◽  
Gunnar Berghöfer ◽  
Roland Ricken ◽  
...  
Keyword(s):  
Prospective Study ◽  
Mood Disorders ◽  
Term Treatment ◽  
Long Term Treatment ◽  
Treatment Refractory ◽  
A Prospective Study

Lithium, valproate, and carbamazepine prescribing patterns for long-term treatment of bipolar I and II disorders: A prospective study

2018 ◽  
Vol 33 (6) ◽  
pp. e2676 ◽  
Author(s):  
Laura Musetti ◽  
Antonio Tundo ◽  
Alessandra Benedetti ◽  
Gabriele Massimetti ◽  
Erika Cambiali ◽  
...  
Keyword(s):  
Prospective Study ◽  
Term Treatment ◽  
Prescribing Patterns ◽  
Long Term Treatment ◽  
A Prospective Study

Comparison of the long-term treatment outcomes of women and men diagnosed with schizophrenia over a period of 20 years. A prospective study

2018 ◽  
Vol 84 ◽  
pp. 62-67 ◽  
Author(s):  
Andrzej Cechnicki ◽  
Anna Bielańska ◽  
Dagmara Mętel ◽  
Katarzyna Susz ◽  
Piotr Błądziński ◽  
...  
Keyword(s):  
Prospective Study ◽  
Treatment Outcomes ◽  
Term Treatment ◽  
Long Term Treatment ◽  
A Prospective Study

Long-term effects of topical corticosteroids in the nose

1992 ◽  
Vol 106 (9) ◽  
pp. 810-812 ◽  
Author(s):  
M. Bende ◽  
J. Mark
Keyword(s):  
Prospective Study ◽  
Nasal Mucosa ◽  
Term Treatment ◽  
Histopathological Changes ◽  
Long Term Effects ◽  
Topical Corticosteroids ◽  
Long Term Treatment ◽  
A Prospective Study

AbstractIn a prospective study, biopsies were taken from the septal mucosa in 21 patients of whom 11 had been using topical nasal corticosteroids. In contrast to the effect of long-term treatment with corticosteroids in the skin, but in accordance with previous investigations of the nasal mucosa, no histopathological changes of significance were found, although the biopsies were taken from different sites. These findings do not suggest that topically corticosteroids are harmful to the nasal mucosa.

scholarly journals A COMPARATIVE STUDY OF INTRAOCULAR PRESSURE CHANGES (OCCURING AS A SIDE EFFECT) IN LONG TERM TREATMENT OF VERNAL KERATO CONJUNCTIVITIS BY TOPICAL FLUROMETHOLONE 0.1% AND TOPICAL LOTEPREDNOL ETABONATE 0.5%

2021 ◽  
pp. 27-28
Author(s):  
Kalishankar Das ◽  
Sneha Bhowmick ◽  
Athokpam Poireiton
Keyword(s):  
Intraocular Pressure ◽  
Prospective Study ◽  
Term Treatment ◽  
Short Term ◽  
Loteprednol Etabonate ◽  
Long Term Treatment ◽  
A Prospective Study ◽  
Pressure Changes

PURPOSE: The study aims to evaluate the safety of topical corticosteroids Loteprednol and Flurometholone in treating VKC keeping in mind the efcacy of the drugs. METHOD: A prospective study was done including 200 eyes of 107 patients with severe VKC (grade 3,4). 7 patients were lost during follow up. Patients were selected randomly. 100 eyes of 50 patients were treated with Flurometholone 1% and another 100 eyes of 50 patients with Loteprednol 0.5%. All patients were followed up over a period of 3 months. The study duration is 18 months. RESULT: The normal IOP ranging between 10-21 mm Hg. Out of 100 eyes receiving urometholone in the study period of 18 months, 3 eyes (3%) showed IOP ≥ 30mm Hg and 5 eyes (5%) showed IOP between 21-30mm Hg. Out of the rest 100 eyes receiving Loteprednol, 3 eyes (3%) showed IOP between 21-30 mm Hg while none (0%) reached an IOP over 30 mm Hg. CONCLUSION: Loteprednol is more effective than Flurometholone and it consistently demonstrated a low propensity to elevate IOP, regardless of formulation, dosage regimen both during short term as well as long term treatment of VKC patient.

The Prevention of Suicide in Patients with Recurrent Mood Disorder

1992 ◽  
Vol 6 (2_suppl) ◽  
pp. 334-339
Author(s):  
Malcolm Peet
Keyword(s):  
Mood Disorder ◽  
Mood Disorders ◽  
Health Workers ◽  
Lithium Treatment ◽  
Term Treatment ◽  
Mental Health Workers ◽  
Long Term Treatment ◽  
Reduced Rate ◽  
Commit Suicide

Recurrent mood disorder carries a risk of suicide of ~ 15%. Patients who do commit suicide have often received inadequate antidepressant or prophylactic lithium treatment. Long-term treatment with lithium normalizes the excess mortality associated with recurrent mood disorders, including that from suicide. A reduced availability of the most lethal methods of suicide may contribute epidemiologically to a reduced rate of suicide, and therefore the differences in overdose toxicity between antidepressants may be pertinent. Education of mental health workers regarding the effective treatment of mood disorders can help to reduce the rate of suicide. Patient education and psychological support can lead to improved compliance with prophylactic medication and early detection of relapse, but more formal psychotherapy does not appear to be helpful. Specialized mood disorder clinics lead to better patient care than is possible in a routine psychiatric out-patient clinic.

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