scholarly journals The influence of comorbid anxiety on the effectiveness of Cognitive Therapy and Interpersonal Psychotherapy for Major Depressive Disorder

2018 ◽  
Vol 232 ◽  
pp. 52-60 ◽  
Author(s):  
Suzanne C. van Bronswijk ◽  
Lotte H.J.M. Lemmens ◽  
Marcus J.H. Huibers ◽  
Arnoud Arntz ◽  
Frenk P.M.L. Peeters
2018 ◽  
Vol 225 ◽  
pp. 530-538 ◽  
Author(s):  
Suzanne C. van Bronswijk ◽  
Lotte H.J.M. Lemmens ◽  
Wolfgang Viechtbauer ◽  
Marcus J.H. Huibers ◽  
Arnoud Arntz ◽  
...  

2018 ◽  
Vol 36 (3) ◽  
pp. 252-261 ◽  
Author(s):  
Suzanne C. van Bronswijk ◽  
Lotte H.J.M. Lemmens ◽  
John R. Keefe ◽  
Marcus J.H. Huibers ◽  
Robert J. DeRubeis ◽  
...  

2011 ◽  
Vol 42 (7) ◽  
pp. 1343-1357 ◽  
Author(s):  
J. C. Jakobsen ◽  
J. L. Hansen ◽  
S. Simonsen ◽  
E. Simonsen ◽  
C. Gluud

BackgroundMajor depressive disorder afflicts an estimated 17% of individuals during their lifetime at tremendous suffering and cost. Cognitive therapy and interpersonal psychotherapy are treatment options, but their effects have only been limitedly compared in systematic reviews.MethodUsing Cochrane systematic review methodology we compared the benefits and harm of cognitive therapy versus interpersonal psychotherapy for major depressive disorder. Trials were identified by searching the Cochrane Library's CENTRAL, Medline via PubMed, EMBASE, Psychlit, PsycInfo, and Science Citation Index Expanded until February 2010. Continuous outcome measures were assessed by mean difference and dichotomous outcomes by odds ratio. We conducted trial sequential analysis to control for random errors.ResultsWe included seven trials randomizing 741 participants. All trials had high risk of bias. Meta-analysis of the four trials reporting data at cessation of treatment on the Hamilton Rating Scale for Depression showed no significant difference between the two interventions [mean difference −1.02, 95% confidence interval (CI) −2.35 to 0.32]. Meta-analysis of the five trials reporting data at cessation of treatment on the Beck Depression Inventory showed comparable results (mean difference −1.29, 95% CI −2.73 to 0.14). Trial sequential analysis indicated that more data are needed to definitively settle the question of a differential effect. None of the included trial reported on adverse events.ConclusionsRandomized trials with low risk of bias and low risk of random errors are needed, although the effects of cognitive therapy and interpersonal psychotherapy do not seem to differ significantly regarding depressive symptoms. Future trials should report on adverse events.


2010 ◽  
Vol 38 (5) ◽  
pp. 561-576 ◽  
Author(s):  
Kate L. Mathew ◽  
Hayley S. Whitford ◽  
Maura A. Kenny ◽  
Linley A. Denson

Background: Mindfulness-based Cognitive Therapy (MBCT) is a relapse prevention treatment for major depressive disorder. Method: An observational clinical audit of 39 participants explored the long-term effects of MBCT using standardized measures of depression (BDI-II), rumination (RSS), and mindfulness (MAAS). Results: MBCT was associated with statistically significant reductions in depression from pre to post treatment. Gains were maintained over time (Group 1, 1–12 months, p = .002; Group 2, 13–24 months, p = .001; Group 3, 25–34 months, p = .04). Depression scores in Group 3 did begin to worsen, yet were still within the mild range of the BDI-II. Treatment variables such as attendance at “booster” sessions and ongoing mindfulness practice correlated with better depression outcomes (p = .003 and p = .03 respectively). There was a strong negative correlation between rumination and mindful attention (p < .001), consistent with a proposed mechanism of metacognition in the efficacy of MBCT. Conclusion: It is suggested that ongoing MBCT skills and practice may be important for relapse prevention over the longer term. Larger randomized studies of the mechanisms of MBCT with longer follow-up periods are recommended.


2008 ◽  
Vol 70 (2) ◽  
pp. 214-222 ◽  
Author(s):  
John C. Markowitz ◽  
Sapana R. Patel ◽  
Ivan C. Balan ◽  
Michelle A. Bell ◽  
Carlos Blanco ◽  
...  

2014 ◽  
Vol 71 (10) ◽  
pp. 1157 ◽  
Author(s):  
Steven D. Hollon ◽  
Robert J. DeRubeis ◽  
Jan Fawcett ◽  
Jay D. Amsterdam ◽  
Richard C. Shelton ◽  
...  

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