scholarly journals The centrality of DSM and non-DSM depressive symptoms in Han Chinese women with major depression

2018 ◽  
Vol 227 ◽  
pp. 739-744 ◽  
Author(s):  
Kenneth S. Kendler ◽  
Steven H. Aggen ◽  
Jonathan Flint ◽  
Denny Borsboom ◽  
Eiko I. Fried
Keyword(s):  
Depressive Symptoms ◽  
Major Depression ◽  
Chinese Women ◽  
Han Chinese

scholarly journals The structure of the symptoms of major depression: exploratory and confirmatory factor analysis in depressed Han Chinese women

2013 ◽  
Vol 44 (7) ◽  
pp. 1391-1401 ◽  
Author(s):  
Y. Li ◽  
S. Aggen ◽  
S. Shi ◽  
J. Gao ◽  
Y. Li ◽  
...  
Keyword(s):  
Factor Analysis ◽  
Depressive Symptoms ◽  
Suicidal Ideation ◽  
Major Depression ◽  
Chinese Women ◽  
Han Chinese ◽  
Psychiatric Interview ◽  
Symptom Dimensions ◽  
Psychiatric Syndrome ◽  
Dsm Iv

BackgroundThe symptoms of major depression (MD) are clinically diverse. Do they form coherent factors that might clarify the underlying nature of this important psychiatric syndrome?MethodSymptoms at lifetime worst depressive episode were assessed at structured psychiatric interview in 6008 women of Han Chinese descent, age ⩾30 years with recurrent DSM-IV MD. Exploratory factor analysis (EFA) and confirmatoryfactor analysis (CFA) were performed in Mplus in random split-half samples.ResultsThe preliminary EFA results were consistently supported by the findings from CFA. Analyses of the nine DSM-IV MD symptomatic A criteria revealed two factors loading on: (i) general depressive symptoms; and (ii) guilt/suicidal ideation. Examining 14 disaggregated DSM-IV criteria revealed three factors reflecting: (i) weight/appetite disturbance; (ii) general depressive symptoms; and (iii) sleep disturbance. Using all symptoms (n = 27), we identified five factors that reflected: (i) weight/appetite symptoms; (ii) general retarded depressive symptoms; (iii) atypical vegetative symptoms; (iv) suicidality/hopelessness; and (v) symptoms of agitation and anxiety.ConclusionsMD is a clinically complex syndrome with several underlying correlated symptom dimensions. In addition to a general depressive symptom factor, a complete picture must include factors reflecting typical/atypical vegetative symptoms, cognitive symptoms (hopelessness/suicidal ideation), and an agitated symptom factor characterized by anxiety, guilt, helplessness and irritability. Prior cross-cultural studies, factor analyses of MD in Western populations and empirical findings in this sample showing risk factor profiles similar to those seen in Western populations suggest that our results are likely to be broadly representative of the human depressive syndrome.

scholarly journals Cognitive trio: relationship with major depression and clinical predictors in Han Chinese women

2013 ◽  
Vol 43 (11) ◽  
pp. 2265-2275 ◽  
Author(s):  
L. Wang ◽  
L. Liu ◽  
S. Shi ◽  
J. Gao ◽  
Y. Liu ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Major Depression ◽  
Stressful Life Events ◽  
Chinese Women ◽  
Age At Onset ◽  
Cognitive Model ◽  
Han Chinese ◽  
Cognitive Symptoms ◽  
Clinical Predictors ◽  
Increased Risk

BackgroundPrevious studies support Beck's cognitive model of vulnerability to depression. However, the relationship between his cognitive triad and other clinical features and risk factors among those with major depression (MD) has rarely been systematically studied.MethodThe three key cognitive symptoms of worthlessness, hopelessness and helplessness were assessed during their lifetime worst episode in 1970 Han Chinese women with recurrent MD. Diagnostic and other risk factor information was assessed at personal interview. Odds ratios (ORs) were calculated by logistic regression.ResultsCompared to patients who did not endorse the cognitive trio, those who did had a greater number of DSM-IV A criteria, more individual depressive symptoms, an earlier age at onset, a greater number of episodes, and were more likely to meet diagnostic criteria for melancholia, postnatal depression, dysthymia and anxiety disorders. Hopelessness was highly related to all the suicidal symptomatology, with ORs ranging from 5.92 to 6.51. Neuroticism, stressful life events (SLEs) and a protective parental rearing style were associated with these cognitive symptoms.ConclusionsDuring the worst episode of MD in Han Chinese women, the endorsement of the cognitive trio was associated with a worse course of depression and an increased risk of suicide. Individuals with high levels of neuroticism, many SLEs and high parental protectiveness were at increased risk for these cognitive depressive symptoms. As in Western populations, symptoms of the cognitive trio appear to play a central role in the psychopathology of MD in Chinese women.

The prevalence, clinical correlates and structure of phobic fears in Han Chinese women with recurrent major depression

2014 ◽  
Vol 157 ◽  
pp. 92-99 ◽  
Author(s):  
Fuzhong Yang ◽  
Jianyin Qiu ◽  
Hongsu Zhao ◽  
Zhoubing Wang ◽  
Danhong Tao ◽  
...  
Keyword(s):  
Major Depression ◽  
Chinese Women ◽  
Han Chinese ◽  
Clinical Correlates

Clinical features of and risk factors for major depression with history of postpartum episodes in Han Chinese women: A retrospective study

2015 ◽  
Vol 183 ◽  
pp. 339-346 ◽  
Author(s):  
Fuzhong Yang ◽  
Charles O. Gardner ◽  
Tim Bigdeli ◽  
Jingfang Gao ◽  
Zhen Zhang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Retrospective Study ◽  
Major Depression ◽  
Clinical Features ◽  
Chinese Women ◽  
Han Chinese ◽  
History Of

scholarly journals Suicidal Risk Factors of Recurrent Major Depression in Han Chinese Women

PLoS ONE ◽  
2013 ◽  
Vol 8 (11) ◽  
pp. e80030 ◽  
Author(s):  
Yuzhang Zhu ◽  
Hongni Zhang ◽  
Shenxun Shi ◽  
Jingfang Gao ◽  
Youhui Li ◽  
...  
Keyword(s):  
Risk Factors ◽  
Major Depression ◽  
Chinese Women ◽  
Han Chinese ◽  
Suicidal Risk

Age at onset of recurrent major depression in Han Chinese women – A replication study

2014 ◽  
Vol 157 ◽  
pp. 72-79 ◽  
Author(s):  
Fuzhong Yang ◽  
Hongsu Zhao ◽  
Zhoubing Wang ◽  
Danhong Tao ◽  
Xue Xiao ◽  
...  
Keyword(s):  
Major Depression ◽  
Chinese Women ◽  
Age At Onset ◽  
Han Chinese ◽  
Replication Study

Shared Genetic Risk between Major Depression and Body Mass Index in Han Chinese Women

2020 ◽  
Vol 87 (9) ◽  
pp. S222
Author(s):  
Roseann Peterson ◽  
Tim Bigdeli ◽  
Bradley Todd Webb ◽  
Jonathan Flint ◽  
Kenneth Kendler
Keyword(s):  
Body Mass Index ◽  
Major Depression ◽  
Body Mass ◽  
Genetic Risk ◽  
Chinese Women ◽  
Han Chinese ◽  
Shared Genetic

scholarly journals A COMPARISON OF MELANCHOLIC AND NONMELANCHOLIC RECURRENT MAJOR DEPRESSION IN HAN CHINESE WOMEN

2011 ◽  
Vol 29 (1) ◽  
pp. 4-9 ◽  
Author(s):  
Ning Sun ◽  
Yihan Li ◽  
Yiyun Cai ◽  
Jing Chen ◽  
Yuan Shen ◽  
...  
Keyword(s):  
Major Depression ◽  
Chinese Women ◽  
Han Chinese

scholarly journals Clinical Features of Patients with Dysthymia in a Large Cohort of Han Chinese Women with Recurrent Major Depression

PLoS ONE ◽  
2013 ◽  
Vol 8 (12) ◽  
pp. e83490 ◽  
Author(s):  
Wenqing Wu ◽  
Zhoubing Wang ◽  
Yan Wei ◽  
Guanghua Zhang ◽  
Shenxun Shi ◽  
...  
Keyword(s):  
Major Depression ◽  
Clinical Features ◽  
Chinese Women ◽  
Han Chinese ◽  
Large Cohort

Dietary Choline Intake during Pregnancy and PEMT rs7946 Polymorphism on Risk of Preterm Birth: A Case-Control Study

2021 ◽  
pp. 1-10
Author(s):  
Jie Zhu ◽  
Yu-Hong Liu ◽  
Xiang-Long He ◽  
Martin Kohlmeier ◽  
Li-Li Zhou ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Case Control Study ◽  
Chinese Women ◽  
Case Control ◽  
Han Chinese ◽  
Food Frequency ◽  
Term Delivery ◽  
Choline Intake ◽  
Dietary Choline ◽  
Control Study

<b><i>Introduction and Aims:</i></b> Choline-metabolizing genetic variation may interact with choline intake on fetal programming and pregnancy outcome. This case-control study aims to explore the association of maternal choline consumption and phosphatidylethanolamine N-methyltransferase (PEMT) gene polymorphism rs7946 with preterm birth risk. <b><i>Methods:</i></b> 145 Han Chinese women with preterm delivery and 157 Han Chinese women with term delivery were recruited in Shanghai. Dietary choline intake during pregnancy was assessed using a validated food frequency questionnaire. Additionally, DNA samples were genotyped for PEMT rs7946 (G5465A) with plasma homocysteine (Hcy) levels measured. <b><i>Results:</i></b> Compared with the lowest quartile of choline intake, women within the highest consumption quartile had adjusted odds ratio (aOR) for preterm birth of 0.48 (95% confidence interval, CI [0.24, 0.95]). There was a significant interaction between maternal choline intake and PEMT rs7946 (<i>p</i> for interaction = 0.04), where the AA genotype carriers who consumed the energy-adjusted choline &#x3c;255.01 mg/day had aOR for preterm birth of 3.75 (95% CI [1.24, 11.35]), compared to those with GG genotype and choline intake &#x3e;255.01 mg/day during pregnancy. Additionally, the greatest elevated plasma Hcy was found in the cases with AA genotype and choline consumption &#x3c;255.01 mg/day (<i>p</i> &#x3c; 0.001). <b><i>Conclusion:</i></b> The AA genotype of PEMT rs7946 may be associated with increased preterm birth in these Han Chinese women with low choline intake during pregnancy.

Sign in / Sign up

Export Citation Format

Share Document