scholarly journals Etiologic specificity of waking Cortisol: Links with maternal history of depression and anxiety in adolescent girls

2017 ◽  
Vol 208 ◽  
pp. 103-109 ◽  
Author(s):  
Brandon L. Goldstein ◽  
Greg Perlman ◽  
Roman Kotov ◽  
Joan E. Broderick ◽  
Keke Liu ◽  
...  
Keyword(s):  
Adolescent Girls ◽  
Depression And Anxiety ◽  
Maternal History ◽  
History Of ◽  
History Of Depression

Effect on Neuropsychiatric Disorders of Organophosphate Pesticides Exposure among Rice Farmers in Sukoharjo, Central Java

2020 ◽  
Author(s):  
Ayu Laela Fitriyani ◽  
◽  
Setyo Sri Rahardjo ◽  
Bhisma Murti ◽  
◽  
...  
Keyword(s):  
Family History ◽  
Work Stress ◽  
Depression And Anxiety ◽  
High Exposure ◽  
Rice Farmers ◽  
Central Java ◽  
Loss And Grief ◽  
History Of ◽  
Family History Of Depression ◽  
History Of Depression

ABSTRACT Background: Chronic exposure to organophosphate pesticides can increase the risk of neuropsychiatric disorders, including depression and anxiety. Unsafe behavior from farmers will endanger the health of farmers, especially in the form of neuropsychiatric disorders (depression and anxiety). This study aimed to analyze the effects of pesticide exposure and psychosocial determinants on depression and anxiety. Subjects and Method: A retrospective cohort study was conducted in Sukoharjo, Central Java. The study population was rice farmers. A sample of 200 rice farmers who use organophospate pesticide was selected by fixed exposure sampling. The dependent variable was neuropsychiatry (anxiety and depression). The independent variables were exposure to organophospate pesticide, had family history of depression, loss and grief, post trauma, work stress, and the use of personal protective equipment (PPE). The data were collected by questionnaire and analyzed by a multiple linear regression. Results: The risk of depression increased with high exposure to organophospate pesticide (b= 0.15; 95% CI= 0.05 to 0.26; p= 0.005), had family history of depression (b= 5.10; 95% CI= 2.60 to 7.60; p<0.001), loss and grief (b= 2.94; 95% CI= 0.76 to 5.11; p= 0.008), post trauma (b= 2.57; 95% CI= 0.24 to 4.89; p= 0.031), and work stress (b= 0.16; 95% CI= 0.05 to 0.27; p= 0.005). The risk of depression decreased with the use of PPE (b= -0.69; 95% CI= -1.32 to -0.076; p= 0.028). The risk of anxiety increased with high exposure to organophospate pesticide (b= 0.13; 95% CI= 0.02 to 0.24; p= 0.025), post trauma (b= 5.96; 95% CI= 3.48 to 8.44; p<0.001), loss and grief (b= 3.39; 95% CI= 1.07 to 5.71; p<0.001), had family history of depression (b= 2.95; 95% CI= 0.29 to 5.62; p= 0.004), and work stress (b= 0.19; 95% CI= 0.07 to 0.30; p=0.002). The risk of anxiety decreased with the use of PPE (b= -0.09; 95% CI= -1.57 to -0.024; p=0.008). Conclusion: The risk of depression increases with high exposure to organophospate pesticide, family history of depression, loss and grief, post trauma, and work stress. The risk of depression decreases with the use of PPE. The risk of anxiety increases with high exposure to organophospate pesticide, post trauma, loss and grief, had family history of depression, and work stress. The risk of anxiety decreases with the use of PPE. Keywords: Neuropsychiatry disorder, depression, anxiety Correspondence: Ayu Laela Fitriyani. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: [email protected]. Mobile: +625796333986. DOI: https://doi.org/10.26911/the7thicph.01.48

Impact of Maternal Early Life Maltreatment and Maternal History of Depression on Child Psychopathology: Mediating Role of Maternal Sensitivity?

2018 ◽  
Vol 50 (2) ◽  
pp. 278-290 ◽  
Author(s):  
Katja Bödeker ◽  
Anna Fuchs ◽  
Daniel Führer ◽  
Dorothea Kluczniok ◽  
Katja Dittrich ◽  
...  
Keyword(s):  
Early Life ◽  
Child Psychopathology ◽  
Maternal Sensitivity ◽  
Maternal History ◽  
Mediating Role ◽  
History Of ◽  
History Of Depression

scholarly journals Suicidal Ideations and Attempts in Patients with Isolated Dystonia

Neurology ◽  
2021 ◽  
pp. 10.1212/WNL.0000000000011596
Author(s):  
Alexis Worthley ◽  
Kristina Simonyan
Keyword(s):  
Suicidal Ideation ◽  
Suicidal Behavior ◽  
Depression And Anxiety ◽  
Electronic Survey ◽  
Increased Risk ◽  
Generalized Dystonia ◽  
History Of ◽  
History Of Depression ◽  
Global Population ◽  
Question Survey

Objective:To evaluate the hypothesis that individuals with isolated dystonia are at an increased risk for suicidal behavior, we administered an anonymous electronic survey to patients with dystonia, asking them about their history of suicidal ideations and suicide attempt.Methods:A total of 542 patients with dystonia completed an online 97-question survey, which captured the demographics of suicidal behavior and major psychiatric disorders in these patients. Statistical analyses examined the prevalence of suicidal behavior in patients with dystonia compared to the prevalence of suicidal ideations and attempt in the general global population and assessed the significance of risk associations between suicidality and psychiatric history in these patients.Results:Overall, 32.3% of patients with isolated dystonia reported a lifetime history of suicidal behavior, which was significantly different from the reported rates of suicidal ideation (9.2%) and attempt (2.7%) in the general global population. The prevalence of suicidality was higher in patients with multifocal/segmental and generalized forms of dystonia (range of 46%-50%) compared to patients with focal dystonias (range of 26.1%-33.3%). The highest suicidal ideation-to-attempt ratio of 4:1 was found in patients with generalized dystonia. Suicidality in patients with focal dystonia was significantly associated with their history of depression and anxiety disorders.Conclusion:Patients with isolated dystonia have an increased, albeit unrecognized, prevalence of suicidal behavior compared to the general global population. The screening for suicidal risk should be incorporated as part of the clinical evaluation of patients with dystonia to prevent their suicide-induced injury and death.

scholarly journals Familial risk for distress and fear disorders and emotional reactivity in adolescence: an event-related potential investigation

2015 ◽  
Vol 45 (12) ◽  
pp. 2545-2556 ◽  
Author(s):  
B. D. Nelson ◽  
G. Perlman ◽  
G. Hajcak ◽  
D. N. Klein ◽  
R. Kotov
Keyword(s):  
Adolescent Girls ◽  
Emotional Reactivity ◽  
Familial Risk ◽  
Event Related Potential ◽  
Parental Distress ◽  
Emotional Stimuli ◽  
Parental History ◽  
Lifetime History ◽  
History Of ◽  
History Of Depression

BackgroundThe late positive potential (LPP) is an event-related potential component that is sensitive to the motivational salience of stimuli. Children with a parental history of depression, an indicator of risk, have been found to exhibit an attenuated LPP to emotional stimuli. Research on depressive and anxiety disorders has organized these conditions into two empirical classes: distress and fear disorders. The present study examined whether parental history of distress and fear disorders was associated with the LPP to emotional stimuli in a large sample of adolescent girls.MethodThe sample of 550 girls (ages 13.5–15.5 years) with no lifetime history of depression completed an emotional picture-viewing task and the LPP was measured in response to neutral, pleasant and unpleasant pictures. Parental lifetime history of psychopathology was determined via a semi-structured diagnostic interview with a biological parent, and confirmatory factor analysis was used to model distress and fear dimensions.ResultsParental distress risk was associated with an attenuated LPP to all stimuli. In contrast, parental fear risk was associated with an enhanced LPP to unpleasant pictures but was unrelated to the LPP to neutral and pleasant pictures. Furthermore, these results were independent of the adolescent girls’ current depression and anxiety symptoms and pubertal status.ConclusionsThe present study demonstrates that familial risk for distress and fear disorders may have unique profiles in terms of electrocortical measures of emotional information processing. This study is also one of the first to investigate emotional/motivational processes underlying the distress and fear disorder dimensions.

scholarly journals Despite worse baseline status depressed patients achieved outcomes similar to those in nondepressed patients after surgery for cervical deformity

2017 ◽  
Vol 43 (6) ◽  
pp. E10 ◽  
Author(s):  
Gregory W. Poorman ◽  
Peter G. Passias ◽  
Samantha R. Horn ◽  
Nicholas J. Frangella ◽  
Alan H. Daniels ◽  
...  
Keyword(s):  
Neck Pain ◽  
Rating Scale ◽  
Japanese Orthopaedic Association ◽  
Clinical Depression ◽  
Depression And Anxiety ◽  
Cervical Deformity ◽  
Depressed Patients ◽  
History Of ◽  
The Impact ◽  
History Of Depression

OBJECTIVEDepression and anxiety have been demonstrated to have negative impacts on outcomes after spine surgery. In patients with cervical deformity (CD), the psychological and physiological burdens of the disease may overlap without clear boundaries. While surgery has a proven record of bringing about significant pain relief and decreased disability, the impact of depression and anxiety on recovery from cervical deformity corrective surgery has not been previously reported on in the literature. The purpose of the present study was to determine the effect of depression and anxiety on patients’ recovery from and improvement after CD surgery.METHODSThe authors conducted a retrospective review of a prospective, multicenter CD database. Patients with a history of clinical depression, in addition to those with current self-reported anxiety or depression, were defined as depressed (D group). The D group was compared with nondepressed patients (ND group) with a similar baseline deformity determined by propensity score matching of the cervical sagittal vertical axis (cSVA). Baseline demographic, comorbidity, clinical, and radiographic data were compared among patients using t-tests. Improvement of symptoms was recorded at 3 months, 6 months, and 1 year postoperatively. All health-related quality of life (HRQOL) scores collected at these follow-up time points were compared using t-tests.RESULTSSixty-six patients were matched for baseline radiographic parameters: 33 with a history of depression and/or current depression, and 33 without. Depressed patients had similar age, sex, race, and radiographic alignment: cSVA, T-1 slope minus C2–7 lordosis, SVA, and T-1 pelvic angle (p > 0.05). Compared with nondepressed individuals, depressed patients had a higher incidence of osteoporosis (21.2% vs 3.2%, p = 0.028), rheumatoid arthritis (18.2% vs 3.2%, p = 0.012), and connective tissue disorders (18.2% vs 3.2%, p = 0.012). At baseline, the D group had greater neck pain (7.9 of 10 vs 6.6 on a Numeric Rating Scale [NRS], p = 0.015), lower mean EQ-5D scores (68.9 vs 74.7, p < 0.001), but similar Neck Disability Index (NDI) scores (57.5 vs 49.9, p = 0.063) and myelopathy scores (13.4 vs 13.9, p = 0.546). Surgeries performed in either group were similar in terms of number of levels fused, osteotomies performed, and correction achieved (baseline to 3-month measurements) (p < 0.05). At 3 months, EQ-5D scores remained lower in the D group (74.0 vs 78.2, p = 0.044), and NDI scores were similar (48.5 vs 39.0, p = 0.053). However, neck pain improved in the D group (NRS score of 5.0 vs 4.3, p = 0.331), and modified Japanese Orthopaedic Association (mJOA) scores remained similar (14.2 vs 15.0, p = 0.211). At 6 months and 1 year, all HRQOL scores were similar between the 2 cohorts. One-year measurements were as follows: NDI 39.7 vs 40.7 (p = 0.878), NRS neck pain score of 4.1 vs 5.0 (p = 0.326), EQ-5D score of 77.1 vs 78.2 (p = 0.646), and mJOA score of 14.0 vs 14.2 (p = 0.835). Anxiety/depression levels reported on the EQ-5D scale were significantly higher in the depressed cohort at baseline, 3 months, and 6 months (all p < 0.05), but were similar between groups at 1 year postoperatively (1.72 vs 1.53, p = 0.416).CONCLUSIONSClinical depression was observed in many of the study patients with CD. After matching for baseline deformity, depression symptomology resulted in worse baseline EQ-5D and pain scores. Despite these baseline differences, both cohorts achieved similar results in all HRQOL assessments 6 months and 1 year postoperatively, demonstrating no clinical impact of depression on recovery up until 1 year after CD surgery. Thus, a history of depression does not appear to have an impact on recovery from CD surgery.

Maternal history of depression is associated with enhanced theory of mind in depressed and nondepressed adult women

2011 ◽  
Vol 189 (1) ◽  
pp. 91-96 ◽  
Author(s):  
Kate Leslie Harkness ◽  
Dustin Washburn ◽  
Jordan Eugene Theriault ◽  
Lisa Lee ◽  
Mark Alan Sabbagh
Keyword(s):  
Theory Of Mind ◽  
Adult Women ◽  
Maternal History ◽  
History Of ◽  
History Of Depression

scholarly journals Parental history of depression or anxiety and the cortisol awakening response

2010 ◽  
Vol 197 (3) ◽  
pp. 180-185 ◽  
Author(s):  
Sophie A. Vreeburg ◽  
Catharina A. Hartman ◽  
Witte J. G. Hoogendijk ◽  
Richard van Dyck ◽  
Frans G. Zitman ◽  
...  
Keyword(s):  
Anxiety Disorders ◽  
Hpa Axis ◽  
Depression And Anxiety ◽  
Major Depressive ◽  
Parental History ◽  
History Of ◽  
Hpa Axis Dysregulation ◽  
Cortisol Levels ◽  
State Factor ◽  
History Of Depression

BackgroundIt is unclear whether altered hypothalamic–pituitary–adrenal (HPA) axis regulation, which frequently accompanies depression and anxiety disorders, represents a trait rather than a state factor.AimsTo examine whether HPA axis dysregulation represents a biological vulnerability for these disorders, we compared cortisol levels in unaffected people with and without a parental history of depressive or anxiety disorders. We additionally examined whether possible HPA axis dysregulations resemble those observed in participants with depression or anxiety disorders.MethodData were from the Netherlands Study of Depression and Anxiety. Within the participants without a lifetime diagnoses of depression or anxiety disorders, three groups were distinguished: 180 people without parental history, 114 with self-reported parental history and 74 with CIDI-diagnosed parental history. These groups were additionally compared with people with major depressive disorder or panic disorder with agoraphobia (n = 1262). Salivary cortisol samples were obtained upon awakening, and 30, 45 and 60 min later.ResultsAs compared with unaffected participants without parental history, unaffected individuals with diagnosed parental history of depression or anxiety showed a significantly higher cortisol awakening curve (effect size (d) = 0.50), which was similar to that observed in the participants with depression or anxiety disorders. Unaffected people with self-reported parental history did not differ in awakening cortisol levels from unaffected people without parental history.ConclusionsUnaffected individuals with parental history of depression or anxiety showed a higher cortisol awakening curve, similar to that of the participants with depression or anxiety disorders. This suggests that a higher cortisol awakening curve reflects a trait marker, indicating an underlying biological vulnerability for the development of depressive and anxiety disorders.

scholarly journals Medical Image of the Month: Severe Acute Respiratory Distress Syndrome and Embolic Strokes from Polymethylmethacrylate (PMMA) Embolization

2021 ◽  
Vol 22 (4) ◽  
pp. 86-87
Author(s):  
Sooraj Kumar ◽  
Sharanyah Srinivasan ◽  
Tammer El-Aini
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Emergency Room ◽  
Medical Image ◽  
Distress Syndrome ◽  
Depression And Anxiety ◽  
History Of ◽  
The Brain ◽  
History Of Depression

No abstract available. Article truncated after 150 words. A 35-year-old lady with a history of depression and anxiety presented to the emergency room with worsening shortness of breath after receiving polymethylmethacrylate (PMMA) injections in her buttock for cosmetic purposes in Mexico. Immediately after the injection in the outpatient office, she became acutely short of breath, tachypneic, and tachycardic. She was brought to the emergency room where she was hypoxic with oxygen saturations in the low 80s on a non-rebreather, tachypneic with a respiratory rate in the 40s, and tachycardic with heart rates in 140s. She was emergently intubated. A CTA of the chest demonstrated bilateral ground glass opacities throughout, most pronounced in the upper lobes which progressed to significant bilateral airspace disease consistent with acute respiratory distress syndrome (Figure 1). Her neurological examination declined over the course of her hospitalization. An MRI of the brain with contrast demonstrated bilateral foci of susceptibility artifact throughout the entirety of the …

Differences in the Clinical Profile of Adolescents and Young Adults with Major Depressive Disorder Across Parental History Groups

2018 ◽  
Author(s):  
Jennifer Gillies
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Clinical Profile ◽  
Major Depressive ◽  
Parental History ◽  
Maternal History ◽  
Offspring Sex ◽  
History Of ◽  
Severity Of Depression ◽  
History Of Depression

An important causal factor of depression is family history ¾ there is compelling evidence that Major Depressive Disorder (MDD) is familial. Although the connection between a maternal history of depression and offspring risk is well established, paternal history has been largely ignored in research thus far. The first goal of this study is to examine differences in the clinical profile of MDD across parental depression history groups (i.e., both-parent history versus maternal history only versus paternal history only versus no parental history).  Based on previous findings, I predict that the severity of the clinical course of MDD (as operationalized by a higher severity of depression and anxiety symptoms, an increased likelihood of recurrence, and a greater likelihood of a comorbid anxiety disorder) will be highest for offspring with a both-parent history of depression, followed by those with a maternal history only, followed by individuals with a paternal history only, and lastly by offspring with no parental history of depression. The second goal is to determine if the group differences hypothesized above are further moderated by offspring sex. To date, very little is known about how parental history influences the clinical presentation of MDD in depressed offspring. This study will contribute to a limited body of research, and is unique in that it will include four parental history groups as well as offspring sex in its analyses. The study will use a quasi-archival sample of approximately 250 participants between 12 and 29 years of age, who have been diagnosed with MDD.

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