scholarly journals Increased fear-potentiated startle in major depressive disorder patients with lifetime history of suicide attempt

2014 ◽  
Vol 162 ◽  
pp. 34-38 ◽  
Author(s):  
Elizabeth D. Ballard ◽  
Dawn F. Ionescu ◽  
Jennifer L. Vande Voort ◽  
Elizabeth E. Slonena ◽  
Jose A. Franco-Chaves ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Suicide Attempt ◽  
Depressive Disorder ◽  
Major Depressive ◽  
Lifetime History ◽  
History Of ◽  
Fear Potentiated Startle

History of suicide attempt and right superior temporal gyrus volume in youth with treatment-resistant major depressive disorder

2018 ◽  
Vol 239 ◽  
pp. 291-294 ◽  
Author(s):  
Quinn McLellan ◽  
T. Christopher Wilkes ◽  
Rose Swansburg ◽  
Natalia Jaworska ◽  
Lisa Marie Langevin ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Suicide Attempt ◽  
Depressive Disorder ◽  
Superior Temporal Gyrus ◽  
Treatment Resistant ◽  
Major Depressive ◽  
History Of

scholarly journals Higher Negative Self-Reference Level in Patients With Personality Disorders and Suicide Attempt(s) History During Biological Treatment for Major Depressive Disorder: Clinical Implications

2021 ◽  
Vol 12 ◽  
Author(s):  
Samuel Bulteau ◽  
Morgane Péré ◽  
Myriam Blanchin ◽  
Emmanuel Poulet ◽  
Jérôme Brunelin ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Symptoms ◽  
Suicide Attempt ◽  
Depressive Disorder ◽  
Personality Disorders ◽  
Past History ◽  
Major Depressive ◽  
Clinical Variables ◽  
History Of ◽  
Self Reference

Objective: The aim of the study was to identify clinical variables associated with changes in specific domains of self-reported depression during treatment by antidepressant and/or repetitive Transcranial Magnetic Stimulation (rTMS) in patients with Major Depressive Disorder (MDD).Methods: Data from a trial involving 170 patients with MDD receiving either venlafaxine, rTMS or both were re-analyzed. Depressive symptoms were assessed each week during the 2 to 6 weeks of treatment with the 13-item Beck Depression Inventory (BDI13). Associations between depression changes on BDI13 domains (Negative Self-Reference, Sad Mood, and Performance Impairment), treatment arm, time, and clinical variables were tested in a mixed linear model.Results: A significant decrease of self-reported depressive symptoms was observed over time. The main characteristics associated with persistent higher depressive symptomatology on Negative Self-Reference domain of the BDI13 were personality disorders (+2.1 points), a past history of suicide attempt(s) (+1.7 points), age under 65 years old (+1.5 points), and female sex (+1.1 points).Conclusions: Early cognitive intervention targeting specifically negative self-referencing process could be considered during pharmacological or rTMS treatment for patients with personality disorders and past history of suicide attempt(s).

O4. Right Superior Temporal Gyrus Volume as a Biomarker of History of Suicide Attempt in Youth With Treatment-Resistant Major Depressive Disorder

2018 ◽  
Vol 83 (9) ◽  
pp. S109
Author(s):  
Quinn McLellan ◽  
T. Christopher Wilkes ◽  
Rose Swansburg ◽  
Natalia Jaworska ◽  
Lisa Marie Langevin ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Suicide Attempt ◽  
Depressive Disorder ◽  
Superior Temporal Gyrus ◽  
Treatment Resistant ◽  
Major Depressive ◽  
History Of

Family study of co-morbidity between major depressive disorder and anxiety disorders

2003 ◽  
Vol 33 (4) ◽  
pp. 703-714 ◽  
Author(s):  
D. N. KLEIN ◽  
P. M. LEWINSOHN ◽  
P. ROHDE ◽  
J. R. SEELEY ◽  
S. A. SHANKMAN
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Anxiety Disorders ◽  
Family Study ◽  
Community Sample ◽  
Major Depressive ◽  
Lifetime History ◽  
First Degree Relatives ◽  
Co Morbidity ◽  
History Of

Background. Numerous studies have documented high rates of co-morbidity between major depressive disorder (MDD) and the anxiety disorders (ANX). However, the reason for this is unclear. Family studies provide one potentially useful approach for addressing this issue.Method. We explored six explanations of the co-morbidity between MDD and ANX using a family study of a large community sample of young adults and their first-degree relatives. Participants included 112 probands with a lifetime history of both MDD and one or more ANX, 290 probands with a history of MDD but no ANX, 43 probands with a history of one or more ANX but no MDD, 352 probands with no lifetime history of either MDD or ANX, and the probands' 2608 first-degree relatives. Probands were assessed using semi-structured diagnostic interviews on two occasions in adolescence and a third time at age 24. Diagnostic data on relatives were collected using both direct and family history interviews.Results. Compared with controls, MDD aggregated in the families of probands with MDD, whether or not they had co-morbid ANX; ANX aggregated in the families of probands with ANX, regardless of whether they had co-morbid MDD; and co-morbid MDD/ANX aggregated only in the families of probands with both MDD and ANX. The relatives of probands with ANX alone had a significantly higher rate of ANX than the relatives of probands with MDD alone, although none of the other comparisons between the depressed and anxious groups were significant.Conclusions. This pattern of findings is largely, although not completely, consistent with the view that MDD and ANX are transmitted independently within families, and suggests that the co-morbidity between MDD and ANX is caused by non-familial aetiological factors.

scholarly journals Binge eating, trauma, and suicide attempt in community adults with major depressive disorder

PLoS ONE ◽  
2018 ◽  
Vol 13 (6) ◽  
pp. e0198192 ◽  
Author(s):  
Ji Hyun Baek ◽  
Kiwon Kim ◽  
Jin Pyo Hong ◽  
Maeng Je Cho ◽  
Maurizio Fava ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Suicide Attempt ◽  
Depressive Disorder ◽  
Binge Eating ◽  
Major Depressive
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