scholarly journals Suicide and history of childhood trauma among street youth

2012 ◽  
Vol 136 (3) ◽  
pp. 377-380 ◽  
Author(s):  
Scott E. Hadland ◽  
Brandon D.L. Marshall ◽  
Thomas Kerr ◽  
Jiezhi Qi ◽  
Julio S. Montaner ◽  
...  
Keyword(s):  
Childhood Trauma ◽  
Street Youth ◽  
History Of Childhood ◽  
History Of

scholarly journals 135. Suicide and History of Childhood Trauma Among Street Youth

2011 ◽  
Vol 48 (2) ◽  
pp. S87-S88
Author(s):  
Scott Hadland ◽  
Thomas Kerr ◽  
Brandon Marshall ◽  
Jiezhi Qi ◽  
Julio Montaner ◽  
...  
Keyword(s):  
Childhood Trauma ◽  
Street Youth ◽  
History Of Childhood ◽  
History Of

scholarly journals Rethinking childhood adversity in chronic fatigue syndrome

2015 ◽  
Author(s):  
James E Clark ◽  
Sean Davidson ◽  
Laura Maclachlan ◽  
Megan Lynn ◽  
Julia L Newton ◽  
...  
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Childhood Trauma ◽  
Childhood Adversity ◽  
Chronic Fatigue ◽  
Childhood Trauma Questionnaire ◽  
History Of Childhood ◽  
Fatigue Syndrome ◽  
Increased Risk ◽  
Co Morbidity ◽  
History Of

Objectives: Previous studies have consistently shown increased rates of childhood adversity in chronic fatigue syndrome (CFS). However, such aetiopathogenic studies of CFS are potentially confounded by co-morbidity and misdiagnosis particularly with depression. We used a modelling approach with existing data and data generated in our examination of the rates of childhood adversity in a sample of CFS patients who had no lifetime history of depression. Methods: The childhood trauma questionnaire (CTQ) was completed by a sample of 52 participants and 19 controls with chronic fatigue syndrome who did not meet criteria for a psychiatric disorder (confirmed using the Structured Clinical Interview for DSM-IV). Subsequently, Mediation Analysis (Baye’s Rules) was used to establish the risk childhood adversity poses for CFS with and without depression. Results: In a cohort of CFS patients with depression robustly excluded, CTQ scores were markedly lower than in all previous studies and, in contrast to these previous studies, not increased compared with healthy controls. Post-hoc analysis showed that CTQ scores correlated with the number of depressive symptoms during the lifetime worst period of low mood. The probability of developing CFS given a history of childhood trauma was shown to be 4%, a two-fold increased risk compared to the general population. However, much of this risk is mediated by the concomitant development of major depression. Discussion: The data suggests that previous studies showing a relationship between childhood adversity and CFS may be mediated by depression

Childhood trauma and being at-risk for psychosis are associated with higher peripheral endocannabinoids

2019 ◽  
Vol 50 (11) ◽  
pp. 1862-1871 ◽  
Author(s):  
E. Appiah-Kusi ◽  
R. Wilson ◽  
M. Colizzi ◽  
E. Foglia ◽  
E. Klamerus ◽  
...  
Keyword(s):  
Risk Factors ◽  
At Risk ◽  
Childhood Trauma ◽  
Childhood Maltreatment ◽  
Peripheral Blood ◽  
Endocannabinoid System ◽  
History Of Childhood ◽  
Increased Risk ◽  
History Of

AbstractBackgroundEvidence has been accumulating regarding alterations in components of the endocannabinoid system in patients with psychosis. Of all the putative risk factors associated with psychosis, being at clinical high-risk for psychosis (CHR) has the strongest association with the onset of psychosis, and exposure to childhood trauma has been linked to an increased risk of development of psychotic disorder. We aimed to investigate whether being at-risk for psychosis and exposure to childhood trauma were associated with altered endocannabinoid levels.MethodWe compared 33 CHR participants with 58 healthy controls (HC) and collected information about previous exposure to childhood trauma as well as plasma samples to analyse endocannabinoid levels.ResultsIndividuals with both CHR and experience of childhood trauma had higher N-palmitoylethanolamine (p < 0.001) and anandamide (p < 0.001) levels in peripheral blood compared to HC and those with no childhood trauma. There was also a significant correlation between N-palmitoylethanolamine levels and symptoms as well as childhood trauma.ConclusionsOur results suggest an association between CHR and/or childhood maltreatment and elevated endocannabinoid levels in peripheral blood, with a greater alteration in those with both CHR status and history of childhood maltreatment compared to those with either of those risks alone. Furthermore, endocannabinoid levels increased linearly with the number of risk factors and elevated endocannabinoid levels correlated with the severity of CHR symptoms and extent of childhood maltreatment. Further studies in larger cohorts, employing longitudinal designs are needed to confirm these findings and delineate the precise role of endocannabinoid alterations in the pathophysiology of psychosis.

Evaluation of an Outpatient Intervention for Women With Severe Depression and a History of Childhood Trauma

2009 ◽  
Vol 60 (7) ◽  
pp. 936-942 ◽  
Author(s):  
Verónica G. Vitriol ◽  
Soledad T. Ballesteros ◽  
Ramón U. Florenzano ◽  
Kristina P. Weil ◽  
Dafna F. Benadof
Keyword(s):  
Childhood Trauma ◽  
Severe Depression ◽  
History Of Childhood ◽  
Outpatient Intervention ◽  
History Of

scholarly journals Recurrence of Depression in Relation to History of Childhood Trauma and Hair Cortisol Concentration in a Community-Based Sample

2019 ◽  
Vol 78 (1) ◽  
pp. 48-57 ◽  
Author(s):  
Roman Duncko ◽  
Susanne Fischer ◽  
Stephani L. Hatch ◽  
Souci Frissa ◽  
Laura Goodwin ◽  
...  
Keyword(s):  
Childhood Trauma ◽  
Cortisol Concentration ◽  
Hair Cortisol ◽  
Community Based ◽  
History Of Childhood ◽  
History Of
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