Prevalence and factors associated with depressive disorders in an HIV+ rural patient population in southern Uganda

2011 ◽  
Vol 135 (1-3) ◽  
pp. 160-167 ◽  
Author(s):  
E. Nakimuli-Mpungu ◽  
S. Musisi ◽  
E. Katabira ◽  
J. Nachega ◽  
J. Bass
2020 ◽  
Vol 277 ◽  
pp. 306-312
Author(s):  
Leonardo Tondo ◽  
Ross J. Baldessarini ◽  
Margherita Barbuti ◽  
Paola Colombini ◽  
Jules Angst ◽  
...  

2019 ◽  
Vol 12 ◽  
pp. 175628481881832 ◽  
Author(s):  
Brian Lacy ◽  
Rajeev Ayyagari ◽  
Annie Guerin ◽  
Andrea Lopez ◽  
Sherry Shi ◽  
...  

Background: Irritable bowel syndrome (IBS) reduces quality of life and burdens healthcare systems. This study identified factors associated with frequent use of IBS diagnostic tests and procedures. Methods: Using a United States claims database (2001–2012), tests and procedures in IBS patients occurring in the 2-year study period (12 months before/following the first IBS diagnosis) were analyzed: endoscopy, GI transit testing, anorectal procedures, and radiologic imaging. Patients were classified based on test/procedure frequency (3+, 1–2, or 0). Multivariate logistic regression identified factors associated with more frequent tests/procedures. Results: Among 201,322 IBS patients, 41.7% had 3+ tests/procedures, 35.1% had 1–2, and 23.3% had 0. Patients with more tests/procedures were older [mean age 50.6 (3+ group), more likely to be female and had more comorbidities, including anxiety, depressive disorders, and somatization. Dyspepsia [odds ratio (95% confidence interval): 1.80 (1.72–1.87)], interstitial cystitis [1.60 (1.45–1.77)], gastroesophageal reflux disease [1.59 (1.55–1.63)], constipation [1.50 (1.45–1.54)], and dyspareunia [1.38 (1.25–1.52)] were significantly associated with more tests/procedures (3+ versus 1–2), while anxiety, depressive disorders, and somatization were not. Patients with more frequent specialist visits [emergency department (ED; 1.10 (1.09–1.11)) and gastroenterologists (1.26 (1.26–1.27))] or at least one GI-related ED visit or inpatient admission [1.95 (1.86–2.04) and 3.67 (3.48–3.87), respectively] were more likely to have more tests/procedures (all p < 0.05). Conclusions: Test frequency in patients with IBS is strongly associated with demographic and clinical characteristics, especially comorbid conditions related to IBS. Presence of common overlapping comorbid conditions should increase clinicians’ confidence in making the diagnosis of IBS, thus curtailing redundant testing and reducing healthcare costs.


2010 ◽  
Vol 25 (3) ◽  
pp. 540.e1-540.e7 ◽  
Author(s):  
Margaret A. Pisani ◽  
Terrence E. Murphy ◽  
Katy L.B. Araujo ◽  
Peter H. Van Ness

2019 ◽  
Vol 25 (3) ◽  
pp. 136-141
Author(s):  
R. I. Isakov

Background. The leading position in the structure of the pathology of the psyche today is convincingly held by depressive disorders. In recent years, the number of publications showing a combination of the frequency of depression and psychosocial maladaptation, which acts both as a derivative in the clinic of depressive disorders and as an independent phenomenon that provokes and aggravates their course, has increased. Objective – to study the correlation of the structure and severity of the manifestations of macrosocial maladaptation and anxiety-depressive symptoms in women with depressive disorders of various genesis, in order to further determine the targeted points for differentiated psychosocial rehabilitation of this patient population. Materials and methods. 252 women with a diagnosis of depressive disorder were examined: 94 women with depressive disorder of psychogenic genesis (F43.21), 83 women with endogenous depression, (F32.0, F32.1, F32.2, F32.3, F33.0, F33. 1, F33.2, F33.3, F31.3, F31.4, F31.5) and 75 women with depressive disorder of organic genesis (F06.3). According to the results of assessing the degree of macrosocial maladaptation, two groups were distinguished: women without signs of maladaptation were assigned to the first group (n=48); the second group (n=204) consisted women with identified signs of maladaptation. We used such research methods: clinical-psychopathological, psychodiagnostic, statistical. Results. The regularities between the genesis of depression and the severity of signs of macrosocial maladaptation and anxiety are established and described. Macrosocial maladaptation of various severity occurs in the vast majority of patients with depression of any genesis. The severity and variability of pathological anxiety is the lowest in women with psychogenic depression with no or mild macrosocial disadaptation, and high in severe maladaptation, meanwhile in patients with endogenous depression the severity of anxiety is highest with mild maladaptation and low with severe macrosocial maladaptation. Conclusions. The severity of macrosocial maladaptation does not demonstrate a direct association with the severity of depressive phenomena and a clear comparability with the genesis of depressive disorder. Anxiety is less dependent on the genesis of depression, and is more determined by the degree of maladaptation. Received data should be taken into account when developing diagnostic, treatment and rehabilitation measures for women with depressive disorders.


2020 ◽  
Vol 29 (1) ◽  
pp. 50-54
Author(s):  
Joseph Davidson ◽  
Samuel Folkard ◽  
Matthew Hinckley ◽  
Elizabeth Uglow ◽  
Oliver Wright ◽  
...  

Introduction: access to water at the bedside is a cornerstone of patient care. Among bedbound inpatients, water within reach at the bedside is a basic human dignity and one that ought not to be neglected. Aim: the authors sought to identify the extent to which accessible hydration facilities were provided to a bedbound inpatient population. Methods: a cross-sectional, point-prevalent audit of hospitalised medical inpatients across five centres was conducted. Data were collected between meal times and noted baseline demographics and admission details, adequacy of oral hydration provision at the bedside and, where provision was inadequate, factors associated with this. Results: across a total surveyed patient population of 559 we identified 138 patients who were bedbound. Among these bedbound patients, 6% (n=8) had no water provided at the bedside. However, 7 of these were deemed to be unable to swallow safely. In total, 44 (32%) of the 138 bedbound patients were unable to reach the water at their bedside; 18 of these patients would have been able to drink for themselves had the water been in reach. Conclusion: there is significant room for improvement in ensuring patients who are immobile are able to reach drinking apparatus at the bedside. In the five centres surveyed, approximately one in five bedbound patients with no contraindication are unable to reach an essential means of hydration.


2012 ◽  
Vol 18 (6) ◽  
pp. 427-433 ◽  
Author(s):  
Henry N. Young ◽  
S. Nadra Havican ◽  
Sara Griesbach ◽  
Joshua M. Thorpe ◽  
Betty A. Chewning ◽  
...  

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1088.1-1088
Author(s):  
A. Abramkin ◽  
T. Lisitsyna ◽  
D. Veltishchev ◽  
O. Seravina ◽  
O. Kovalevskaya ◽  
...  

Background:Anxiety and depressive disorders (ADD) significantly affect disease activity and functional disability in rheumatoid arthritis (RA) patients. Psychopharmacotherapy (PPT) of ADD attempts to improve RA disease activity and lower progression of functional limitations.Objectives:To determine factors associated with HAQ treatment response in antidepressants-treated RA-patients at five years endpoint.Methods:128 RA-patients (pts) were enrolled, 86% were women with a mean age of 47,4±11,3 (M±SD) yrs. All patients met the full ACR/EULAR 2010 criteria for RA. Functional limitations were assessed using Health Assessment Questionnaire (HAQ), mean HAQ was 1,42±0,78 at baseline. 69,4% RA-pts were already taking prednisone (9 [5; 10] mg/day (Me (25%; 75%)), 84,4% - cDMARDs, 7,8% - bDMARDs (anti-TNF-α – 6,3%, rituximab – 1,6%). ADD were diagnosed by psychiatrist in 123 (96,1%) of RA-pts in accordance with ICD-10 in semi-structured interview. Severity of depression and anxiety was evaluated with Montgomery–Asberg Depression Rating Scale (MADRS) and Hamilton Anxiety Rating Scale (HAM-A). RA-pts with ADD were divided into the following treatment groups: 1 – сDMARDs (n=39), 2 – сDMARDs + PPT (sertraline or mianserine) (n=43), 3 – сDMARDs + bDMARDs (n=32), 4 – сDMARDs + bDMARDs + PPT (sertraline or mianserine) (n=9). Biologics treatment duration varied from 1 to 6 years, antidepressants – from 6 to 96 weeks. Baseline HAQ scores were 1,39±0,75, 1,42±0,9, 1,58±0,76 and 1,38±0,83 in groups 1-4, respectively. At 5-yrs endpoint in 83 RA-pts differences between baseline and endpoint HAQ scores (Δ HAQ = endpoint HAQ – baseline HAQ) were assessed as HAQ treatment response with minimal clinically important difference (MCID) (Δ HAQ ≥ 0,22). HAQ response rates were 4,2%, 65,5%, 47,6% and 76,7% in groups 1-4, respectively, with the lowest response rate in group 1 (p<0,0001). Logistic regression analysis was conducted to determine factors associated with RA remission rate.Results:By univariate logistic regression, anxiety and depressive symptoms remission at 5-yrs endpoint, baseline HAQ and major depression, lower baseline age, BMI and DAS28, no minor depression and cardiovascular diseases at baseline were significantly (p≤0,2) associated with HAQ treatment response (table 1). These variables were subjected to multivariate stepwise logistic regression. Only remission of anxiety and depressive symptoms at 5-yrs endpoint (OR 6,6 (95%CI 1,78 – 24,43), p=0,005), higher baseline HAQ (OR 2,61 (95%CI 1,12 – 6,11), p=0,027) and lower baseline BMI (OR 0,9 (95%CI 0,85 – 0,96), p=0,001) were independently associated with HAQ treatment response at 5-years follow-up.Table 1.Factors associated with RA remission at 5 years (univariate logistic regression).FactorpOR95%CIlowupAnxiety and depressive symptoms remission at 5-yrs endpoint0,0075,01,56116,016Baseline HAQ0,012,6571,2645,588Baseline major depression0,1422,0820,7825,542Baseline age0,0980,9920,9821,002Body mass index (BMI)0,0480,9810,9631,0Baseline minor depression0,1670,5630,2491,273Cardiovascular diseases0,10,4170,1471,183Baseline DAS280,0080,0771,0712,096Conclusion:higher HAQ and lower BMI at baseline and remission of anxiety and depressive symptoms at 5-yrs endpoint are independently associated with HAQ treatment response (MCID) at 5-years follow-up.Disclosure of Interests:None declared


2017 ◽  
Vol 51 ◽  
pp. 106 ◽  
Author(s):  
Danielle Teles da Cruz ◽  
Marcel de Toledo Vieira ◽  
Ronaldo Rocha Bastos ◽  
Isabel Cristina Gonçalves Leite

OBJECTIVE: To analyze if demographic and socioeconomic factors and factors related to health and health services are associated with frailty in community-dwelling older adults. METHODS: This is a cross-sectional study with 339 older adults (60 years old or more) living in Juiz de Fora, State of Minas Gerais, Brazil, in 2015. A household survey was carried out and frailty was evaluated using the Edmonton Frail Scale. For the analysis of the factors associated with outcome, a theoretical model of determination was constructed with three hierarchical blocks: block 1 with demographic and socioeconomic characteristics, block 2 with the health of the older adult (divided into three sub-levels: 2.1 self-reported health variables, 2.2 selfperceived health variables, and 2.3 geriatric syndromes), and block 3 with characteristics related to health services. The variables were adjusted in relation to each other within each block; those with significance level ≤ 0.20 were included in the Poisson regression model and adjusted to a higher level, considering a level of significance of 5%. RESULTS: The prevalence of frailty among older adults was 35.7% (95%CI 30.7–40.9). Of the total, 42.2% did not present frailty; 22.1% were apparently vulnerable. Among the frail ones, 52.9% presented mild frailty, 32.2% moderate frailty, and 14.9% severe frailty. Frailty was associated with difficulty walking, need for an auxiliary device to walk, presence of caregiver, depressive disorders, and functional dependence to perform instrumental activities of daily living. CONCLUSIONS: Frailty is frequent among the older population and it is associated with health variables of the three sub-levels that make up block 2 of the theoretical hierarchical model of determination: self-reported health variables, self-perceived health variables, and geriatric syndromes.


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