Physical treatments for bipolar disorder: A review of electroconvulsive therapy, stereotactic surgery and other brain stimulation techniques

2011 ◽  
Vol 132 (1-2) ◽  
pp. 1-13 ◽  
Author(s):  
Colleen Loo ◽  
Natalie Katalinic ◽  
Philip B. Mitchell ◽  
Benjamin Greenberg
Author(s):  
E. S. Paykel ◽  
J. Scott

This chapters looks at the evidence behind the various medication and physical treatments for mood disorders, before discussing the management options themselves, including the treatment of unipolar disorder, medication, electroconvulsive therapy, treatment of non-response and resistant depression, longer-term treatment, psychological treatments, and continuation and maintenance therapy. The treatment of bipolar disorder is also covered in detail.


2011 ◽  
Vol 27 (2) ◽  
pp. 153-164 ◽  
Author(s):  
Marcio Versiani ◽  
Elie Cheniaux ◽  
J. Landeira-Fernandez

2015 ◽  
Vol 17 (8) ◽  
pp. 892-901 ◽  
Author(s):  
Pierpaolo Medda ◽  
Cristina Toni ◽  
Federica Luchini ◽  
Michela Giorgi Mariani ◽  
Mauro Mauri ◽  
...  

2017 ◽  
Vol 33 (4) ◽  
pp. e40-e41 ◽  
Author(s):  
Laura Kranaster ◽  
Suna Su Aksay ◽  
Jan Malte Bumb ◽  
Christian Wisch ◽  
Michael Deuschle ◽  
...  

2006 ◽  
Vol 8 (2) ◽  
pp. 241-258 ◽  

Until recently, a review of nonpharmacological, somatic treatments of psychiatric disorders would have included only electroconvulsive therapy (ECT). This situation is now changing very substantially. Although ECT remains the only modality in widespread clinical use, several new techniques are under investigation. Their principal indication in the psychiatric context is the treatment of major depression, but other applications are also being studied. All the novel treatments involve brain stimulation, which is achieved by different technological methods. The treatment closest to the threshold of clinical acceptability is transcranial magnetic stimulation (TMS). Although TMS is safe and relatively easy to administer, its efficacy has still to be definitively established. Other modalities, at various stages of research development, include magnetic seizure therapy (MST), deep brain stimulation (DBS), and vagus nerve stimulation (VNS). We briefly review the development and technical aspects of these treatments, their potential role in the treatment of major depression, adverse effects, and putative mechanism of action. As the only one of these treatment modalities that is in widespread clinical use, more extended consideration is given to ECT Although more than half a century has elapsed since ECT was first introduced, it remains the most effective treatment for major depression, with efficacy in patients refractory to antidepressant drugs and an acceptable safety profile. Although they hold considerable promise, the novel brain stimulation techniques reviewed here will be need to be further developed before they achieve clinical acceptability.


2011 ◽  
Vol 27 (2) ◽  
pp. 123-126 ◽  
Author(s):  
Gian Paolo Minnai ◽  
Pier Giorgio Salis ◽  
Rosanna Oppo ◽  
Anna Paola Loche ◽  
Filomena Scano ◽  
...  

2021 ◽  
Vol 11 (73) (1) ◽  
pp. 226-233
Author(s):  
Simona Trifu ◽  
Elena Mănicu ◽  
Milu Petruţ ◽  
Adrian Nicu Lupu

Electroconvulsive therapy (ECT) generated many controversies over time. The clinical literature establishing the efficacy of ECT is among the most solid for any medical treatment, and has been extensively reviewed; however, both practitioners and patients seem to be still reluctant on this issue. In the following review we are aiming at raising the level of awareness among the interested parties regarding ECT. Epidemiological evidence shows that there are a growing number of cases in which ECT has a great benefit, among the most notable being pharmacological resistant depressive disorder, bipolar disorder, schizophrenia, catatonia and others. Current guidelines seem to be overly-prudent regarding ECT indications, in spite of a growing body of research attesting to its importance. Side effects of ECT range from somatic to cognitive and, with a careful prior examination, most are acute and can be managed in a few minutes. An exception to this is the cognitive impairment, which can last from a few hours to a few weeks and presents a reason to reconsider ECT in elderly patients with an important preexisting cognitive impairment.


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