scholarly journals Clinical correlates of planned, more lethal suicide attempts in major depressive disorder

2009 ◽  
Vol 112 (1-3) ◽  
pp. 237-242 ◽  
Author(s):  
Atsuo Nakagawa ◽  
Michael F. Grunebaum ◽  
Maria A. Oquendo ◽  
Ainsley K. Burke ◽  
Haruo Kashima ◽  
...  
2017 ◽  
Vol 4 (2) ◽  
Author(s):  
Dr. Syed Ummer. I ◽  
Dr. Sushith Sugathan. C

Background: Suicide has a strong association with mental disorder and contributes to the excess mortality of the mentally ill. Suicidal ideation is prevalent and appears to be a precondition for suicide attempts among psychiatric patients with Major Depressive disorder. Though ideas and attempts may overlap there are studies that show the two are separate clinical entities with unique psycho-socio demographic profile. Aim: To study correlates in patients with suicidal ideation and those with suicide attempts in a cohort of major depressive disorder patients. Methodology:  Study was conducted at the Inpatient psychiatry unit at a private medical college in Coimbatore, Tamil Nadu. It was a Cross sectional study design. Patients consecutively admitted with major depressive disorder (DSM IV TR) were recruited. Severity of suicidal ideations and attempts were rated on validated scales and the socio demographic and clinical correlates were analyzed. Results: Clinical correlates like severity of depression, severity of suicidal ideation and history of past suicidal attempt were positively correlated with severity of suicidal ideation as well as severity of current suicidal attempts in the cohort of depressive disorder patients. Conclusion: Assessment of current episode severity of both suicidal ideation as well as suicidal attempt is important in identifying high risk patients with major depressive disorder.


Gene ◽  
2017 ◽  
Vol 603 ◽  
pp. 34-41 ◽  
Author(s):  
Shitao Rao ◽  
Cherry She Ting Leung ◽  
Macro Hb Lam ◽  
Yun Kwok Wing ◽  
Mary Miu Yee Waye ◽  
...  

2020 ◽  
Vol 10 ◽  
Author(s):  
Lifei Wang ◽  
Yimeng Zhao ◽  
Elliot K. Edmiston ◽  
Fay Y. Womer ◽  
Ran Zhang ◽  
...  

2020 ◽  
Vol Volume 13 ◽  
pp. 1147-1157
Author(s):  
Angélica Gonçalves Peter ◽  
Mariane Lopez Molina ◽  
Taiane de Azevedo Cardoso ◽  
Thaíse Campos Mondin ◽  
Ricardo Azevedo da Silva ◽  
...  

2010 ◽  
Vol 41 (7) ◽  
pp. 1407-1417 ◽  
Author(s):  
M. S. van Noorden ◽  
S. E. Minkenberg ◽  
E. J. Giltay ◽  
M. E. den Hollander-Gijsman ◽  
Y. R. van Rood ◽  
...  

BackgroundPre-adult onset of major depressive disorder (MDD) may predict a more severe phenotype of depression. As data from naturalistic psychiatric specialty care settings are scarce, we examined phenotypic differences between pre-adult and adult onset MDD in a large sample of consecutive out-patients.MethodAltogether, 1552 out-patients, mean age 39.2±11.6 years, were diagnosed with current MDD on the Mini-International Neuropsychiatric Interview Plus diagnostic interview as part of the usual diagnostic procedure. A total of 1105 patients (71.2%) had complete data on all variables of interest. Pre-adult onset of MDD was defined as having experienced the signs and symptoms of a first major depressive episode before the age of 18 years. Patients were stratified according to the age at interview (20–40/40–65 years). Correlates of pre-adult onset were analysed using logistic regression models adjusted for age, age squared and gender.ResultsUnivariate analyses showed that pre-adult onset of MDD had a distinct set of demographic (e.g. less frequently living alone) and clinical correlates (more co-morbid DSM-IV – Text Revision diagnoses, more social phobia, more suicidality). In the multivariate model, we found an independent association only for a history of suicide attempts [odds ratio (OR) 3.15, 95% confidence intervals (CI) 1.97–5.05] and current suicidal thoughts (OR 1.81, 95% CI 1.26–2.60) in patients with pre-adult versus adult onset MDD.ConclusionsPre-adult onset of MDD is associated with more suicidality than adult onset MDD. Age of onset of depression is an easy to ascertain characteristic that may help clinicians in weighing suicide risk.


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