Maternal obesity, gestational weight gain, and risk of asthma and atopic disease in offspring: A study within the Danish National Birth Cohort

2013 ◽  
Vol 131 (4) ◽  
pp. 1033-1040 ◽  
Author(s):  
Maria C. Harpsøe ◽  
Saima Basit ◽  
Peter Bager ◽  
Jan Wohlfahrt ◽  
Christine Stabell Benn ◽  
...  
Keyword(s):  
Weight Gain ◽  
Birth Cohort ◽  
Gestational Weight Gain ◽  
Maternal Obesity ◽  
Atopic Disease ◽  
Gestational Weight ◽  
Danish National Birth Cohort

Obesity, gestational weight gain and preterm birth: a study within the Danish National Birth Cohort

2007 ◽  
Vol 21 (1) ◽  
pp. 5-14 ◽  
Author(s):  
Ellen Aagaard Nohr ◽  
Bodil Hammer Bech ◽  
Michael Vaeth ◽  
Kathleen M. Rasmussen ◽  
Tine Brink Henriksen ◽  
...  
Keyword(s):  
Weight Gain ◽  
Preterm Birth ◽  
Birth Cohort ◽  
Gestational Weight Gain ◽  
Gestational Weight ◽  
Danish National Birth Cohort

scholarly journals Cause-Specific Stillbirth and Neonatal Death According to Prepregnancy Obesity and Early Gestational Weight Gain: A Study in the Danish National Birth Cohort

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1676
Author(s):  
Ellen Aagaard Nohr ◽  
Sanne Wolff ◽  
Helene Kirkegaard ◽  
Chunsen Wu ◽  
Anne-Marie Nybo Andersen ◽  
...  
Keyword(s):  
Weight Gain ◽  
Birth Cohort ◽  
Gestational Weight Gain ◽  
Neonatal Death ◽  
Causes Of Death ◽  
Normal Weight ◽  
Neonatal Deaths ◽  
Gestational Weight ◽  
Prepregnancy Bmi ◽  
Danish National Birth Cohort

Maternal obesity is associated with impaired fetal and neonatal survival, but underlying mechanisms are poorly understood. We examined how prepregnancy BMI and early gestational weight gain (GWG) were associated with cause-specific stillbirth and neonatal death. In 85,822 pregnancies in the Danish National Birth Cohort (1996–2002), we identified causes of death from medical records for 272 late stillbirths and 228 neonatal deaths. Prepregnancy BMI and early GWG derived from an early pregnancy interview and Cox regression were used to estimate associations with stillbirth or neonatal death as a combined outcome and nine specific cause-of-death categories. Compared to women with normal weight, risk of stillbirth or neonatal death was increased by 66% with overweight and 78% with obesity. Especially deaths due to placental dysfunction, umbilical cord complications, intrapartum events, and infections were increased in women with obesity. More stillbirths and neonatal deaths were observed in women with BMI < 25 and low GWG. Additionally, unexplained intrauterine death was increased with low GWG, while more early stillbirths were seen with both low and high GWG. In conclusion, causes of death that relate to vascular and metabolic disturbances were increased in women with obesity. Low early GWG in women of normal weight deserves more clinical attention.

scholarly journals Association of gestational weight gain with cesarean section: a prospective birth cohort study in Southwest China

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Lujiao Huang ◽  
Ju Zhang ◽  
Hong Sun ◽  
Hongli Dong ◽  
Run Li ◽  
...  
Keyword(s):  
Weight Gain ◽  
Cesarean Section ◽  
Birth Cohort ◽  
Gestational Weight Gain ◽  
Southwest China ◽  
The Other ◽  
Public Health Issue ◽  
Birth Cohort Study ◽  
Gestational Weight ◽  
Prospective Birth Cohort

Abstract Background Cesarean section (CS) is a rising public health issue globally, and is particularly serious in China. Numerous studies have suggested that gestational weight gain (GWG) control may be an effective way to reduce the rate of CS. However, rare study has examined the association between GWG and CS among women in Southwest China. We proposed to examine their association based on a prospective birth cohort, and further to explore the optimal GWG range. Methods We retrieved data from a prospective birth cohort from Sichuan Provincial Hospital for Women and Children, Southwest China. Unconditional multivariable logistic regression was used to examine the association between GWG and CS by adjusting for potential confounders. In one analysis, we incorporated the GWG as a categorical variable according to the Institute of Medicine (IOM) recommendation, similar to the method used in the majority of previous studies. In the other analysis, we directly incorporated GWG as a continuous variable and natural cubic splines were used to characterize the potential nonlinear exposure-response relationship, aiming to identify the optimal GWG. We further stratified the above analysis by pre-pregnancy BMI and GDM, and then a heterogeneity test based on a multivariate meta-analysis was conducted to examine whether the stratum specific estimations agreed with each other. Results A total of 1363 participants were included. By adopting the IOM recommendation, the adjusted OR of CS was 0.63 (0.47, 0.84) for insufficient GWG and 1.42 (1.06, 1.88) for excessive GWG. After stratification by pre-pregnancy BMI, we found a higher risk of CS in associated with excessive GWG in the stratum of underweight compared with the other strata, which implied that pre-pregnancy BMI may be an effect modifier. By applying a flexible spline regression, the optimal GWG levels in terms of reducing the CS rate based on our data were more stringent than those of IOM recommendation, which were 9–12 kg for underweight women, < 19 kg for normal weight women and < 10 kg for overweight/obese women. Conclusions These results suggested that a more stringent recommendation should be applied in Southwest China, and that more attention should be given to underweight women.

scholarly journals Paternal and maternal obesity but not gestational weight gain is associated with type 1 diabetes

2018 ◽  
Vol 47 (2) ◽  
pp. 417-426 ◽  
Author(s):  
Maria C Magnus ◽  
Sjurdur F Olsen ◽  
Charlotta Granstrom ◽  
Nicolai A Lund-Blix ◽  
Jannet Svensson ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Weight Gain ◽  
Gestational Weight Gain ◽  
Maternal Obesity ◽  
Gestational Weight

scholarly journals Impact of maternal obesity on pregnancy course and maternal and perinatal complications

2020 ◽  
Vol 71 (3) ◽  
pp. 54-58
Author(s):  
Milan Lacković
Keyword(s):  
Risk Factors ◽  
Weight Gain ◽  
Gestational Weight Gain ◽  
Pregnancy Complications ◽  
Maternal Obesity ◽  
Overweight And Obesity ◽  
Perinatal Complications ◽  
Anthropometric Parameter ◽  
Gestational Weight ◽  
Excessive Gestational Weight Gain

 The prevalence of obesity and obesity-related health problems is increasing worldwide, especially among woman and man of reproductive age and obesity is designated as one of the most important global health threats in 21st century.  Pregnancy in obese woman is considered as a high-risk pregnancy. Pre-pregnancy obesity and excessive gestational weight gain (GWG) are distinct risk factors with differing associated adverse outcomes, but they could also carry a cumulative negative impact on pregnancy course. Pre-pregnancy obesity is the anthropometric parameter most strongly correlated with perinatal complications. Maternal complications following obesity include antepartum, intrapartum and postpartum complications, such as pregnancy related hypertension, preeclampsia, gestational diabetes mellitus, preterm birth, venous thromboembolism, labor dystocia, labor induction, instrumental and cesarean delivery. Fetal complications related to maternal obesity might include increased prevalence of congenital anomalies, growth abnormalities, prematurity and stillbirth. Pre- pregnancy overweight and obesity is a potentially modifiable risk factor compromising pregnancy outcome. Among all complications that might arise during pregnancy and that could not be predicted and therefore prevented, pre- pregnancy overweight and obesity management control can significantly reduce potential pregnancy complications. Pre-conceptual counseling should provide in a timely manner awareness of this arising medical condition and provide risk reduction of complications following pre- pregnancy obesity and excessive GWG  obesity, pre-pregnancy obesity, excessive gestational weight gain, pregnancy risk factors, pregnancy complications  

scholarly journals Maternal obesity and gestational weight gain: associations with maternal and infant outcomes

2018 ◽  
Vol 77 (OCE3) ◽  
Author(s):  
L. Cassidy ◽  
M.S. Mulhern ◽  
R.M. Alhomaid ◽  
M.B.E. Livingstone ◽  
J.C. Abayomi ◽  
...  
Keyword(s):  
Weight Gain ◽  
Gestational Weight Gain ◽  
Maternal Obesity ◽  
Infant Outcomes ◽  
Gestational Weight ◽  
Maternal And Infant Outcomes

Maternal obesity, gestational weight gain and childhood cardiac outcomes: role of childhood body mass index

2016 ◽  
Vol 40 (7) ◽  
pp. 1070-1078 ◽  
Author(s):  
L Toemen ◽  
O Gishti ◽  
L van Osch-Gevers ◽  
E A P Steegers ◽  
W A Helbing ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Weight Gain ◽  
Gestational Weight Gain ◽  
Body Mass ◽  
Maternal Obesity ◽  
Gestational Weight ◽  
Cardiac Outcomes ◽  
Childhood Body Mass Index

Maternal Obesity and Gestational Weight Gain in Rural Versus Urban Dwelling Women in South Carolina

2012 ◽  
Vol 29 (1) ◽  
pp. 1-11 ◽  
Author(s):  
Alexa Gallagher ◽  
Jihong Liu ◽  
Janice C. Probst ◽  
Amy B. Martin ◽  
Jeffrey W. Hall
Keyword(s):  
South Carolina ◽  
Weight Gain ◽  
Gestational Weight Gain ◽  
Maternal Obesity ◽  
Gestational Weight
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