scholarly journals Hepatocellular Carcinoma Metastatic to the Right Ventricle

2013 ◽  
Vol 61 (4) ◽  
pp. e77 ◽  
Author(s):  
Lakshman Subrahmanyan ◽  
Erik Stilp ◽  
Marcin Bujak ◽  
Daniel Cornfeld ◽  
Lissa Sugeng
2014 ◽  
Vol 12 (4) ◽  
pp. A25-A26 ◽  
Author(s):  
Masahiko Tameda ◽  
Katsuya Shiraki ◽  
Yoshiyuki Takei

Kanzo ◽  
1999 ◽  
Vol 40 (12) ◽  
pp. 667-671 ◽  
Author(s):  
Hideki SHISHIDO ◽  
Hiroshi ISHII ◽  
Hiroshi NAKAMURA ◽  
Masaaki EBARA

Author(s):  
Kosuke Saku ◽  
Nobuhiro Tahara ◽  
Yoshihiro Fukumoto ◽  
Hiroyuki Tanaka

Abstract Background Hepatocellular carcinoma (HCC) that metastasizes to the right ventricle has rarely been reported. An important link between epithelial–mesenchymal transition (EMT) and the invasion and metastasis of cancer cells has recently been demonstrated. However, there are few reports on the relationship between HCC metastasized to the heart and EMT. Case summary We here report the case of a 74-year-old woman who had type C HCC referred to our hospital with general fatigue due to a right ventricular tumour diagnosed at a general hospital. Anticoagulation therapy was done, but the mass had rapidly grown. We performed surgical resection of the mass. Histopathological examination revealed that the tumour was diagnosed as a poorly differentiated HCC metastasis induced by EMT. Discussion Isolated metastasis of HCC to the right ventricle is extremely rare. The HCC with EMT has a potentially high risk of metastasizing to the heart and other organs, and the prognosis is poor.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Xin-tong Zhang ◽  
Ying Li ◽  
Si-hua Ren ◽  
Wei-dong Ren ◽  
Guang Song ◽  
...  

Abstract Background Hepatocellular carcinoma (HCC) with right ventricle metastasis without inferior vena cava and right atrium involvement is very rare and the prognosis of HCC with RV metastasis is generally poor. The mass in the cardiac chamber may lead to lethal instability of hemodynamics, however, the initial symptom is probably non-specific, which means that diagnosis timely becomes even harder. Case presentation We present a 63-year-old male with isolated metastasis of HCC in the right ventricle which caused inflow obstruction. Moreover, we reviewed a series of studies of isolated metastasis of hepatocellular carcinoma between 1980 and 2018, and summarized the relative outcomes. Conclusions Isolated metastasis of hepatocellular carcinoma in the right ventricle is extraordinarily rare. It may damage cardiac structure and broke hemodynamic balance. Multimodality imaging plays an important in accurate pre-operation assessment. Nowadays, palliative treatments could relieve fatal symptoms to some degree, however, standard treatment has not been well established.


2005 ◽  
Vol 53 (2) ◽  
pp. 123-125 ◽  
Author(s):  
S. Haw-Han Chieng ◽  
C.-H. Lin ◽  
M.-J. Lu ◽  
C.-R. Hung

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
George R. Marzouka ◽  
Apurva Badheka ◽  
Alexis P. Rodriguez ◽  
Sandra V. Chaparro

Hepatocellular carcinoma (HCC) is the sixth most prevalent cancer in the world, but metastatic disease to the heart is rare. We present a case of a 63-year-old man with history of hepatitis C and cirrhosis, which had progressed to HCC. The patient had undergone two prior liver transplantations. He presented to the hospital complaining of worsening lower extremity edema. His exam was also pertinent for jugular venous distension, a 3/6 crescendo-decrescendo murmur, and hepatosplenomegaly. A transthoracic echocardiogram showed a large irregular lobulated mass in the apex of the right ventricle with a mobile pedunculated component. An MRI of the heart revealed a 4.4 × 3.4 × 4.0 cm mass within the right ventricular apex, which was subsequently biopsied and found to be moderately differentiated HCC with myocardial fragments. The patient opted out of any further therapy, or intervention, and was enrolled in hospice care.


Medicine ◽  
2016 ◽  
Vol 95 (51) ◽  
pp. e5544 ◽  
Author(s):  
Su Bin Kim ◽  
Yoon Cheol Shin ◽  
Sung Uk Kwon

2000 ◽  
Vol 61 (6) ◽  
pp. 1542-1546
Author(s):  
Setsujyo SHIOTA ◽  
Ichiro KONISHI ◽  
Naoki SATO ◽  
Kazuyoshi HOSHINO ◽  
Shinji KAJITANI ◽  
...  

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