Clinical meaningfulness of complete skin clearance in psoriasis

2016 ◽  
Vol 75 (1) ◽  
pp. 77-82.e7 ◽  
Author(s):  
Bruce Strober ◽  
Kim A. Papp ◽  
Mark Lebwohl ◽  
Kristian Reich ◽  
Carle Paul ◽  
...  
Keyword(s):  
Clinical Meaningfulness

O1-05-03: CONSORTIA DRIVEN APPROACH TO ADDRESSING CLINICAL MEANINGFULNESS IN EARLY AD

2014 ◽  
Vol 10 ◽  
pp. P137-P137 ◽  
Author(s):  
Michael T. Ropacki ◽  
Kristin Hannesdottir ◽  
Suzanne Hendrix ◽  
Mark F. Gordon ◽  
Diane Stephenson ◽  
...  
Keyword(s):  
Clinical Meaningfulness

scholarly journals Function and clinical meaningfulness of treatments for mild Alzheimer's disease

2016 ◽  
Vol 2 (1) ◽  
pp. 105-112 ◽  
Author(s):  
Eric Siemers ◽  
Karen Chilcott Holdridge ◽  
Karen L. Sundell ◽  
Hong Liu‐Seifert
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Clinical Meaningfulness

scholarly journals CLINICALLY MEANINGFUL CHANGE FOR PHYSICAL PERFORMANCE: PERSPECTIVES OF THE ICFSR TASK FORCE

2019 ◽  
pp. 1-5
Author(s):  
J. Guralnik ◽  
K. Bandeen-Roche ◽  
S.a.r. Bhasin ◽  
S. Eremenco ◽  
F. Landi ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Physical Performance ◽  
Performance Measures ◽  
Patient Reported Outcomes ◽  
Task Force ◽  
Meaningful Change ◽  
Patient Reported ◽  
Research Task ◽  
Definition Of ◽  
Clinical Meaningfulness

For clinical studies of sarcopenia and frailty, clinically meaningful outcome measures are needed to monitor disease progression, evaluate efficacy of interventions, and plan clinical trials. Physical performance measures including measures of gait speed and other aspects of mobility and strength have been used in many studies, although a definition of clinically meaningful change in performance has remained unclear. The International Conference on Frailty and Sarcopenia Research Task Force (ICFSR-TF), a group of academic and industry scientists investigating frailty and sarcopenia, met in Miami Beach, Florida, USA in February 2019 to explore approaches for establishing clinical meaningfulness in a manner aligned with regulatory authorities. They concluded that clinical meaningful change is contextually dependent, and that both anchor- based and distribution-based methods of quantifying physical function are informative and should be evaluated relative to patient-reported outcomes. In addition, they identified additional research needed to enable setting criteria for clinical meaningful change in trials.

scholarly journals P3-031: CLINICAL MEANINGFULNESS OF SHORT-TERM COGNITIVE DECLINE ON THE PRECLINICAL ALZHEIMER'S COGNITIVE COMPOSITE-5 (PACC-5) IN NORMAL OLDER ADULTS WITH ELEVATED β-AMYLOID

2019 ◽  
Vol 15 ◽  
pp. P937-P938
Author(s):  
Kate V. Papp ◽  
Rachel F. Buckley ◽  
Elizabeth C. Mormino ◽  
Paul Maruff ◽  
Victor L. Villemagne ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Decline ◽  
Short Term ◽  
Β Amyloid ◽  
Clinical Meaningfulness
Sign in / Sign up

Export Citation Format

Share Document