49.5 EXPLORING THE NEURO-MORPHOLOGICAL AND EPIGENETIC PATHWAY FOR ADVERSE CHILDHOOD EXPERIENCES AND BORDERLINE PERSONALITY DISORDER: A REVIEW

2020 ◽  
Vol 59 (10) ◽  
pp. S246-S247
Author(s):  
Pranita Mainali ◽  
Dinesh Sangroula
Keyword(s):  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Adverse Childhood Experiences ◽  
Borderline Personality ◽  
Childhood Experiences ◽  
Adverse Childhood

scholarly journals Borderline personality disorder symptoms in relation to adverse childhood experiences and balance performance

2019 ◽  
Vol 14 ◽  
pp. 200167 ◽  
Author(s):  
Dorothea Thekkumthala ◽  
Maggie Schauer ◽  
Martina Ruf-Leuschner ◽  
Benjamin Kraus ◽  
Markus Gruber ◽  
...  
Keyword(s):  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Adverse Childhood Experiences ◽  
Borderline Personality ◽  
Balance Performance ◽  
Childhood Experiences ◽  
Adverse Childhood

scholarly journals An eye-tracking study of interpersonal threat sensitivity and adverse childhood experiences in borderline personality disorder

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Katja I. Seitz ◽  
Johanna Leitenstorfer ◽  
Marlene Krauch ◽  
Karen Hillmann ◽  
Sabrina Boll ◽  
...  
Keyword(s):  
Personality Disorder ◽  
Eye Tracking ◽  
Childhood Trauma ◽  
Facial Expressions ◽  
Adverse Childhood Experiences ◽  
Borderline Personality ◽  
Childhood Experiences ◽  
Adverse Childhood ◽  
Interpersonal Threat ◽  
Threat Hypersensitivity

Abstract Background Previous eye-tracking studies provide preliminary evidence for a hypersensitivity to negative, potentially threatening interpersonal cues in borderline personality disorder (BPD). From an etiological point of view, such interpersonal threat hypersensitivity might be explained by a biological vulnerability along with a history of early life adversities. The objective of the current study was to investigate interpersonal threat hypersensitivity and its association with adverse childhood experiences (ACE) in patients with BPD employing eye-tracking technology. Methods We examined a sample of 46 unmedicated, adult female patients with BPD and 25 healthy female volunteers, matched on age and intelligence, with a well-established emotion classification paradigm with angry, fearful, happy, and neutral facial expressions. ACE were assessed retrospectively with the Childhood Trauma Questionnaire. Results Patients as compared to healthy volunteers reflexively directed their gaze more quickly towards the eyes of emotional and neutral faces and did not adapt their fixation patterns according to the facial expression presented. Misclassifying emotional and neutral faces as angry correlated positively with the patients’ self-reported ACE. Conclusions Building on and extending earlier findings, our results are likely to suggest a visual hypervigilance towards the eyes of emotional and neutral facial expressions and a childhood trauma-related anger bias in patients with BPD. Given the lack of a clinical control group, the question whether these findings are specific for BPD has to remain open. Thus, further research is needed to elucidate the specificity of altered visual attention allocation and the role of ACE in anger recognition in patients with BPD.

Borderline personality disorder and emotion dysregulation

2019 ◽  
Vol 31 (3) ◽  
pp. 1143-1156 ◽  
Author(s):  
Alexander L. Chapman
Keyword(s):  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Emotion Dysregulation ◽  
Interpersonal Relations ◽  
Borderline Personality ◽  
Great Promise ◽  
Childhood Experiences ◽  
Developmental Models ◽  
Adverse Childhood ◽  
The Individual

AbstractBorderline personality disorder (BPD) is a severe and complex disorder characterized by instability across many life domains, including interpersonal relations, behavior, and emotions. A core feature and contributor to BPD, emotion dysegulation (ED), consists of deficits in the ability to regulate emotions in a manner that allows the individual to pursue important goals or behave effectively in various contexts. Biosocial developmental models of BPD have emphasized a transaction of environmental conditions (e.g., invalidating environments and adverse childhood experiences) with key genetically linked vulnerabilities (e.g., impulsivity and emotional vulnerability) in the development of ED and BPD. Emerging evidence has begun to highlight the complex, heterotypic pathways to the development of BPD, with key heritable vulnerability factors possibly interacting with aspects of the rearing environment to produce worsening ED and an adolescent trajectory consisting of self-damaging behaviors and eventual BPD. Adults with BPD have shown evidence of a variety of cognitive, physiological, and behavioral characteristics of ED. As the precursors to the development of ED and BPD have become clearer, prevention and treatment efforts hold great promise for reducing the long-term suffering, functional impairment, and considerable societal costs associated with BPD.

scholarly journals Childhood maltreatment, personality vulnerability profiles, and borderline personality disorder symptoms in adolescents

2021 ◽  
pp. 1-14
Author(s):  
Daniela Marchetti ◽  
Pasquale Musso ◽  
Maria Cristina Verrocchio ◽  
Giovanna Manna ◽  
Daniel C. Kopala-Sibley ◽  
...  
Keyword(s):  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Childhood Maltreatment ◽  
Significant Risk ◽  
Borderline Personality ◽  
Personality Profiles ◽  
Childhood Experiences ◽  
Mediation Analyses ◽  
Personality Vulnerability ◽  
Personality Vulnerabilities

Abstract Adverse childhood experiences are significant risk factors in the development of adolescent borderline personality disorder symptoms (BPDs). Theorists have posited that two personality vulnerabilities factors, self-criticism and dependency, may inform our understanding of this relationship. However, no research has examined the associations between early negative experiences, personality vulnerabilities, and adolescent BPDs. The current study aimed to identify profiles of dependency and self-criticism to examine the associations of these profiles with cumulative forms of childhood maltreatment (CM) and BPDs as well as to explore the mediating and moderating role of vulnerable personality profiles in the relationship between cumulative CM and BPDs. Two hundred and forty-one nonclinical and clinical adolescents participated in the study (Mage = 16.37, SD = 1.84). The findings indicated three different profiles: average dependent profile, dependent and self-critical profile, and self-critical profile. Individuals in the average dependent profile presented lower levels of CM and BPDs. Mediation analyses showed that relative to the average dependent profile, a higher cumulative CM history predicted a higher probability of belonging in the dependent and self-critical profile or the self-critical profile and, in turn, this was associated with higher levels of BPDs. No moderating effects of profiles of dependency and self-criticism were found.

scholarly journals Experiences of women living with borderline personality disorder

2016 ◽  
Vol 21 ◽  
pp. 110-119 ◽  
Author(s):  
N. Ntshingila ◽  
M. Poggenpoel ◽  
C. P.H. Myburgh ◽  
A. Temane
Keyword(s):  
Mental Health ◽  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Interpersonal Relationships ◽  
Life Story ◽  
Borderline Personality ◽  
Childhood Experiences ◽  
Educational Challenges ◽  
Contextual Study ◽  
Experiences Of Women

There is limited understanding of the experiences of women living with borderline personality disorder. It was therefore decided to discover how women living with this disorder would tell their life story. For the researcher, who worked in a psychotherapy ward where most women were living with borderline personality disorder, the care of these women was of vital importance, as they were less understood by mental health care providers.The research aimed to explore and describe the experiences of women living with borderline personality disorder. A qualitative, explorative, descriptive and contextual study design was used. Data was collected through in-depth phenomenological interviews that focused on the central question, “Tell me your life story”. Eight participants living with borderline personality disorder were interviewed. Tesch's method for data analysis was used (Creswell, 2009:186), along with an independent coder. Measures to ensure trustworthiness and ethical principles were applied throughout the research. From the findings obtained by means of the interviews of women living with borderline personality disorder, it was evident that there were childhood experiences of living in an unsafe space, related to unhealthy family dynamics, boundary violations and educational challenges. They experienced chronic feelings of emptiness in their relationships with theself. They also presented with a pattern of unstable interpersonal relationships and compromised mental health, which was apparent through the early on set of mental problems, emotional upheaval, looking for emotional escape and having different triggerfactors. Lastly, all these women yearned for facilitated mental health.

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