26.3 FAMILIAL RISK FOR MAJOR MOOD DISORDERS REFLECTED IN THE SPEECH OF CHILDREN AND ADOLESCENTS

2020 ◽  
Vol 59 (10) ◽  
pp. S306
Author(s):  
Sheri Rempel
Keyword(s):  
Children And Adolescents ◽  
Mood Disorders ◽  
Familial Risk

Emotional cognition subgroups in unaffected first-degree relatives of patients with mood disorders

2021 ◽  
pp. 1-11
Author(s):  
Hanne Lie Kjærstad ◽  
Cristina Varo ◽  
Iselin Meluken ◽  
Eduard Vieta ◽  
Maj Vinberg ◽  
...  
Keyword(s):  
Mood Disorders ◽  
Familial Risk ◽  
Hierarchical Cluster ◽  
Expression Recognition ◽  
Neurocognitive Performance ◽  
Cognitive Markers ◽  
First Degree Relatives ◽  
Probe Test ◽  
Data Driven Approach ◽  
Emotional Cognition

Abstract Background Patients with major depressive disorder (MDD) or bipolar disorder (BD) exhibit difficulties with emotional cognition even during remission. There is evidence for aberrant emotional cognition in unaffected relatives of patients with these mood disorders, but studies are conflicting. We aimed to investigate whether emotional cognition in unaffected first-degree relatives of patients with mood disorders is characterised by heterogeneity using a data-driven approach. Methods Data from 94 unaffected relatives (33 of MDD patients; 61 of BD patients) and 203 healthy controls were pooled from two cohort studies. Emotional cognition was assessed with the Social Scenarios Test, Facial Expression Recognition Test and Faces Dot-Probe Test. Hierarchical cluster analysis was conducted using emotional cognition data from the 94 unaffected relatives. The resulting emotional cognition clusters and controls were compared for emotional and non-emotional cognition, demographic characteristics and functioning. Results Two distinct clusters of unaffected relatives were identified: a relatively ‘emotionally preserved’ cluster (55%; 40% relatives of MDD probands) and an ‘emotionally blunted’ cluster (45%; 29% relatives of MDD probands). ‘Emotionally blunted’ relatives presented with poorer neurocognitive performance (global cognition p = 0.010), heightened subsyndromal mania symptoms (p = 0.004), lower years of education (p = 0.004) and difficulties with interpersonal functioning (p = 0.005) than controls, whereas ‘emotionally preserved’ relatives were comparable to controls on these measures. Conclusions Our findings show discrete emotional cognition profiles that occur across healthy first-degree relatives of patients with MDD and BD. These emotional cognition clusters may provide insight into emotional cognitive markers of genetically distinct subgroups of individuals at familial risk of mood disorders.

Mood Disorders in Children and Adolescents

2008 ◽  
pp. 335-354
Author(s):  
Elizabeth B. Weller ◽  
Angelica L. Kloos ◽  
Jessica L. Weisbrot ◽  
Ronald A. Weller
Keyword(s):  
Children And Adolescents ◽  
Mood Disorders

scholarly journals 11.2 Adjunctive L-Methylfolate in Children and Adolescents With Mood Disorders

2021 ◽  
Vol 60 (10) ◽  
pp. S177
Author(s):  
Emily A. Bopp ◽  
Ethan Poweleit ◽  
Marley O. Cox ◽  
Jeffrey Strawn ◽  
Jenni E. Farrow ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Mood Disorders

F127. Neural Correlates of Emotion Processing in Youth at Familial Risk for Mood Disorders

2019 ◽  
Vol 85 (10) ◽  
pp. S262-S263
Author(s):  
Akua Nimarko ◽  
Sarthak Angal ◽  
Corrina Fonseca ◽  
Esther Rah ◽  
Whitney Tang ◽  
...  
Keyword(s):  
Mood Disorders ◽  
Emotion Processing ◽  
Familial Risk ◽  
Neural Correlates

Recent Undesirable Life Events and Psychiatric Disorder in Childhood and Adolescence

1985 ◽  
Vol 147 (5) ◽  
pp. 517-523 ◽  
Author(s):  
Ian Goodyer ◽  
Israel Kolvin ◽  
Sonia Gatzanis
Keyword(s):  
Children And Adolescents ◽  
Mood Disorders ◽  
Emotional Disturbance ◽  
Life Events ◽  
Negative Impact ◽  
Structured Interview ◽  
Childhood And Adolescence ◽  
Presenting Symptoms ◽  
Community Controls ◽  
Severe Degree

A sample of children and adolescents (n = 157) attending a child psychiatry outpatient clinic with conduct or emotional disturbance were compared with community controls (n = 76) for the number and type of recent life events. A Life Events Schedule for children and adolescents was developed and used as a semi-structured interview. Four clinical groups were identified according to their predominant presenting symptoms (conduct, mild mood, severe mood, or somatic). An excess of events carrying a severe degree of negative impact was found for all four groups, compared with matched controls. Eleven classes of events were examined: there is a suggestion that two classes (marital/family, accident/illness) may be more important for conduct and mild mood disorders, and that a further class (permanent separations, termed exits) may be more important for somatic and severe mood disorders.

Homocysteine and MTHFR C677T polymorphism in children and adolescents with psychotic and mood disorders

2013 ◽  
Vol 68 (2) ◽  
pp. 129-136 ◽  
Author(s):  
Laura Kevere ◽  
Santa Purvina ◽  
Daiga Bauze ◽  
Marcis Zeibarts ◽  
Raisa Andrezina ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Mood Disorders ◽  
Mthfr C677t ◽  
C677t Polymorphism ◽  
Mthfr C677t Polymorphism
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