37.4 Pharmacologic Treatment of Anxiety Disorders and Obsessive-Compulsive Disorder in Children and Adolescents With Autism Spectrum Disorder

2017 ◽  
Vol 56 (10) ◽  
pp. S55
Author(s):  
Matthew Siegel
Keyword(s):  
Autism Spectrum Disorder ◽  
Anxiety Disorders ◽  
Children And Adolescents ◽  
Obsessive Compulsive Disorder ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Pharmacologic Treatment ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Adolescents With Autism

scholarly journals Anxiety Disorders and Obsessive-Compulsive Disorder in Individuals with Autism Spectrum Disorder

2017 ◽  
Vol 19 (12) ◽  
Author(s):  
Valentina Postorino ◽  
Connor M. Kerns ◽  
Giacomo Vivanti ◽  
Jessica Bradshaw ◽  
Martina Siracusano ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Anxiety Disorders ◽  
Obsessive Compulsive Disorder ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

Adapted cognitive behavior therapy for obsessive–compulsive disorder with co-occurring autism spectrum disorder: A clinical effectiveness study

Autism ◽  
2019 ◽  
Vol 24 (1) ◽  
pp. 190-199
Author(s):  
Oskar Flygare ◽  
Erik Andersson ◽  
Helene Ringberg ◽  
Anna-Clara Hellstadius ◽  
Johan Edbacken ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Obsessive Compulsive Disorder ◽  
Behavior Therapy ◽  
Cognitive Behavior Therapy ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Cognitive Behavior ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

Obsessive–compulsive disorder and autism spectrum disorder commonly co-occur. Adapted cognitive behavior therapy for obsessive–compulsive disorder in adults with autism spectrum disorder has not previously been evaluated outside the United Kingdom. In this study, 19 adults with obsessive–compulsive disorder and autism spectrum disorder were treated using an adapted cognitive behavior therapy protocol that consisted of 20 sessions focused on exposure with response prevention. The primary outcome was the clinician-rated Yale–Brown Obsessive–Compulsive Scale. Participants were assessed up to 3 months after treatment. There were significant reductions on the Yale–Brown Obsessive–Compulsive Scale at post-treatment (d = 1.5), and improvements were sustained at follow-up (d = 1.2). Self-rated obsessive–compulsive disorder and depressive symptoms showed statistically significant reductions. Improvements in general functioning and quality of life were statistically non-significant. Three participants (16%) were responders at post-treatment and four (21%) were in remission from obsessive–compulsive disorder. At follow-up, three participants (16%) were responders and one (5%) was in full remission. Adapted cognitive behavior therapy for obsessive–compulsive disorder in adults with co-occurring autism spectrum disorder is associated with reductions in obsessive–compulsive symptoms and depressive symptoms. However, outcomes are modest; few patients were completely symptom free, and treatment engagement was low with few completed exposures and low adherence to homework assignments. We identify and discuss the need for further treatment refinement for this vulnerable group.

A Case Report of Intensive Exposure-Based Cognitive Behavioral Therapy for a Child With Comorbid Autism Spectrum Disorder and Obsessive-Compulsive Disorder

2017 ◽  
Vol 31 (2) ◽  
pp. 118-123
Author(s):  
Katie L. Merricks ◽  
Joshua M. Nadeau ◽  
Amaya Ramos ◽  
Eric A. Storch
Keyword(s):  
Autism Spectrum Disorder ◽  
Cognitive Behavioral Therapy ◽  
Obsessive Compulsive Disorder ◽  
Treatment Modality ◽  
Behavioral Therapy ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Cognitive Behavioral ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

Cognitive behavioral therapy (CBT) with exposure and response prevention (ERP) has proven to be an effective treatment modality for children with obsessive-compulsive disorder (OCD). Less research exists demonstrating efficacy for this treatment modality among children with comorbid diagnoses of OCD and autism spectrum disorder (ASD), and virtually, nothing has been reported examining intensive interventions for the most severe cases. As such, this article discusses the treatment of an adolescent male with severe OCD comorbid with ASD, attention deficit hyperactivity disorder (ADHD), generalized anxiety disorder (GAD), and chronic tic disorder using a cognitive behavioral approach and ERP. We conclude with recommendations for continued clinical research to understand approaches to help nonresponders to standard therapeutic approaches with this challenging population.

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