Therapeutic vaccines for colorectal cancer: The progress and future prospect

2020 ◽  
Vol 88 ◽  
pp. 106944
Author(s):  
Mina Shahnazari ◽  
Pouria Samadi ◽  
Mona Pourjafar ◽  
Akram Jalali
Keyword(s):  
Colorectal Cancer ◽  
Future Prospect ◽  
Therapeutic Vaccines

scholarly journals Recent Advances on Immune Targeted Therapy of Colorectal Cancer Using bi-Specific Antibodies and Therapeutic Vaccines

2021 ◽  
Vol 23 (1) ◽  
Author(s):  
Ali Azadi ◽  
Alireza Golchini ◽  
Sina Delazar ◽  
Fatemeh Abarghooi Kahaki ◽  
Seyed Mohsen Dehnavi ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Dendritic Cells ◽  
Monoclonal Antibodies ◽  
Cancer Vaccines ◽  
Epigenetic Alterations ◽  
Therapeutic Approaches ◽  
Therapeutic Vaccines ◽  
Specific Antibodies ◽  
Keywords Cancer ◽  
New Perspective

AbstractColorectal cancer (CRC) is a universal heterogeneous disease that is characterized by genetic and epigenetic alterations. Immunotherapy using monoclonal antibodies (mAb) and cancer vaccines are substitute strategies for CRC treatment. When cancer immunotherapy is combined with chemotherapy, surgery, and radiotherapy, the CRC treatment would become excessively efficient. One of the compelling immunotherapy approaches to increase the efficiency of CRC therapy is the deployment of therapeutic mAbs, nanobodies, bi-specific antibodies and cancer vaccines, which improve clinical outcomes in patients. Also, among the possible therapeutic approaches for CRC patients, gene vaccines in combination with antibodies are recently introduced as a new perspective. Here, we aimed to present the current progress in CRC immunotherapy, especially using Bi-specific antibodies and dendritic cells mRNA vaccines. For this aim, all data were extracted from Google Scholar, PubMed, Scopus, and Elsevier, using keywords cancer vaccines; CRC immunotherapy and CRC mRNA vaccines. About 97 articles were selected and investigated completely based on the latest developments and novelties on bi-specific antibodies, mRNA vaccines, nanobodies, and MGD007.

Therapeutic Vaccines for Colorectal Cancer

2004 ◽  
Vol 3 (5) ◽  
pp. 299-316
Author(s):  
Philip M Arlen ◽  
James L Gulley
Keyword(s):  
Colorectal Cancer ◽  
Therapeutic Vaccines

Therapeutic vaccines against melanoma and colorectal cancer

Vaccine ◽  
2001 ◽  
Vol 19 (17-19) ◽  
pp. 2571-2575 ◽  
Author(s):  
Jim Tartaglia ◽  
Marie-Claude Bonnet ◽  
Neil Berinstein ◽  
Brian Barber ◽  
Michel Klein ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Therapeutic Vaccines

Deletion mapping on chromosome 6 in colorectal cancer associated with ulcerative colitis

2001 ◽  
Vol 120 (5) ◽  
pp. A121-A122
Author(s):  
T EZAKI ◽  
M WATANABE ◽  
S FUNAKOSHI ◽  
M NAGANUMA ◽  
T AZUMA ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Ulcerative Colitis ◽  
Deletion Mapping ◽  
Chromosome 6

Predicting adherence to colorectal cancer surveillance after plypectomy

2001 ◽  
Vol 120 (5) ◽  
pp. A602-A602
Author(s):  
S RAWL ◽  
S BLACKBURN ◽  
L HACKWARD ◽  
N FINEBERG ◽  
T IMPERIALE ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Surveillance ◽  
Colorectal Cancer Surveillance

Urokinase type plasminogen activator and inhibitor type-1 plasma levels in colorectal cancer

2001 ◽  
Vol 120 (5) ◽  
pp. A599-A600 ◽  
Author(s):  
L HERSZENYI ◽  
F FARINATI ◽  
G ISTVAN ◽  
M PAOLI ◽  
G ROVERONI ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Plasminogen Activator ◽  
Plasma Levels ◽  
Type Plasminogen Activator ◽  
Urokinase Type Plasminogen Activator ◽  
Inhibitor Type

A panel of mono- and dinucleotide microsatellite markers is required for reliable determination of the MSI status in colorectal cancer

2001 ◽  
Vol 120 (5) ◽  
pp. A599-A599
Author(s):  
C ARNOLD ◽  
A GOEL ◽  
J CARETHERS ◽  
L WASSERMAN ◽  
C COMPTON ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Microsatellite Markers ◽  
Reliable Determination

Use of plasma MMP-2 to measure response to surgery and chemoradiotherapy in colorectal cancer

2001 ◽  
Vol 120 (5) ◽  
pp. A159-A159
Author(s):  
M TUTTON ◽  
M GEORGE ◽  
S ECCLES ◽  
I SWIFT ◽  
M ABULAFI
Keyword(s):  
Colorectal Cancer
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