Polyvalent immunoglobulin therapy and sepsis-induced immunosuppression

2012 ◽  
Vol 12 (3) ◽  
pp. 539 ◽  
Author(s):  
Fabienne Venet ◽  
Guillaume Monneret
Keyword(s):  
Immunoglobulin Therapy ◽  
Polyvalent Immunoglobulin

Efficacy of Intravenous Immunoglobulin Therapy in Childhood Atopic Dermatitis

2012 ◽  
Vol 18 (1) ◽  
pp. 26-31
Author(s):  
Eun Kyeong Yeon ◽  
A Young Park ◽  
Sanghoon Chae ◽  
Seung Soo Kim ◽  
Kyeong Bae Park ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Intravenous Immunoglobulin ◽  
Immunoglobulin Therapy ◽  
Intravenous Immunoglobulin Therapy

Immune Thrombocytopenia in an Adolescent with Hashimoto’s Thyroiditis – Case Report

2019 ◽  
Vol 4 (3) ◽  
pp. 145-149 ◽  
Author(s):  
Izabella Kelemen ◽  
Zsuzsanna Erzsébet Papp ◽  
Mária Adrienne Horváth
Keyword(s):  
Platelet Count ◽  
Autoimmune Diseases ◽  
Hashimoto’S Thyroiditis ◽  
Clinical Signs ◽  
Immunoglobulin Therapy ◽  
Peripheral Blood Smear ◽  
Bleeding Complications ◽  
Hashimoto's Thyroiditis ◽  
Line Treatment ◽  
First Line

Abstract Introduction: In childhood, thrombocytopenia caused by transient antibody-mediated thrombocyte destruction is most frequently diagnosed as immune thrombocytopenic purpura (ITP). We report the case of a girl with ITP associated with autoimmune thyroiditis. Case presentation: A 11-year-old female patient with Hashimoto’s thyroiditis presented with clinical signs of petechiae and ecchymoses on the extremities. Laboratory tests showed remarkable thrombocytopenia with a platelet count of 44,500/μL, hence she was referred to a hematologic consultation. The peripheral blood smear showed normal size platelets in very low range. The bone marrow examination exposed hyperplasia of the megakaryocyte series with outwardly morphologic abnormalities. The patient was diagnosed with ITP, and her first-line treatment was pulsed steroid and immunoglobulin therapy. The thrombocytopenia was refractory to these first-line medications. After 6 months of corticotherapy and a period of severe menorrhagia, azathioprine immunosupression was initiated as a second-line treatment. Her platelet count rapidly increased, and the evolution was good, without bleeding complications. Conclusion: In case of a medical history of autoimmune diseases and treatment-resistant ITP, attention must be focused on detecting coexisting autoimmune diseases and adjusting the treatment in accordance with the chronic evolution of the disease.

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