Mesenchymal stem cells increase skin graft survival time and up-regulate PD-L1 expression in splenocytes of mice

2017 ◽  
Vol 182 ◽  
pp. 39-49 ◽  
Author(s):  
Ali Moravej ◽  
Bita Geramizadeh ◽  
Negar Azarpira ◽  
Amir-Hassan Zarnani ◽  
Ramin Yaghobi ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Survival Time ◽  
Graft Survival ◽  
Skin Graft

Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo

2002 ◽  
Vol 30 (1) ◽  
pp. 42-48 ◽  
Author(s):  
Amelia Bartholomew ◽  
Cord Sturgeon ◽  
Mandy Siatskas ◽  
Karen Ferrer ◽  
Kevin McIntosh ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Graft Survival ◽  
Skin Graft ◽  
Lymphocyte Proliferation ◽  
Proliferation In Vitro

Stro-1–Positive Human Mesenchymal Stem Cells Prolong Skin Graft Survival in Mice

2013 ◽  
Vol 45 (2) ◽  
pp. 726-729 ◽  
Author(s):  
Y. Zhang ◽  
D. Zhao ◽  
C. Tian ◽  
F. Li ◽  
X. Li ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Graft Survival ◽  
Skin Graft ◽  
Human Mesenchymal Stem Cells

Effect of Mesenchymal Stem Cells on Skin Graft to Flap Prefabrication

2010 ◽  
Vol 65 (2) ◽  
pp. 237-244 ◽  
Author(s):  
Cagri A. Uysal ◽  
Rei Ogawa ◽  
Feng Lu ◽  
Hiko Hyakusoku ◽  
Hiroshi Mizuno
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Skin Graft

Abstract 587: A Randomized Study Evaluating Outcomes of Cardiopulmonary Resuscitation in Rats with Myocardial Infarction Treated with Three Delivery Methods of Mesenchymal Stem Cells

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Tong Wang ◽  
Zhi Wan ◽  
Wanchun Tang ◽  
Shijie Sun ◽  
Zitong Huang ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Cardiopulmonary Resuscitation ◽  
Survival Time ◽  
Myocardial Function ◽  
Left Ventricular ◽  
Left Ventricular Cavity ◽  
Intramyocardial Injection ◽  
Administration Routes

We investigated the effect of allogeneic mesenchymal stem cells (MSCs) on myoardial function following cardiopulmonary resuscitation (CPR) in a rat model of myocardial infarction. We further investigated the efficacy of three routes of MSCs administration including intravenous, intraventricular and intramyocardial injection. Regardless of administration routes, MSCs would improve myocardial function after CPR in myocardial infarction animals. Myocardial infarction was induced by ligation of the left anterior descending coronary artery in 54 rats (6 groups, 9 rats for each). One month later, animals were randomized to receive injection of 5×10 6 MSCs labeled with PKH26 or PBS alone as a placebo into right femoral vein or left ventricular cavity or the infarction zone in the anterior ventricular free wall. Four weeks after injection, 6 minutes of untreated ventricular fibrillation (VF) followed by 6 minutes of CPR were performed prior to defibrillation. Hemodynamics, including cardiac index (CI), dp/dt40, −dp/dt and left ventricular diastolic pressure(LVDP) were measured before induction of VF (baseline) and hourly following resuscitation. There were siginificant improvements in CI, dp/dt40(Figure 1 ), −dp/dt, LVDP after CPR in MSCs treated animals, regardless of the sites of injection. Survival time after CPR was siginificantly increased in MSCs trearted groups comparing with the corresponding PBS treated groups. Independent of administration routes, myocardial function and survival time after CPR were comparably improved in all groups treated with MSCs in constrast to the PBS groups. Figure 1

Antigen-Specific T-Regulatory Cells Can Extend Skin Graft Survival Time in Mice

2011 ◽  
Vol 43 (5) ◽  
pp. 2033-2040
Author(s):  
S. Yu ◽  
B. Fu ◽  
X. He ◽  
X. Peng ◽  
A. Hu ◽  
...  
Keyword(s):  
Survival Time ◽  
Graft Survival ◽  
Skin Graft ◽  
T Regulatory Cells ◽  
Regulatory Cells

scholarly journals Adipose- and Bone Marrow–Derived Mesenchymal Stem Cells Prolong Graft Survival in Vascularized Composite Allotransplantation

2015 ◽  
Vol 99 (9) ◽  
pp. 1765-1773 ◽  
Author(s):  
Jan A. Plock ◽  
Jonas T. Schnider ◽  
Wensheng Zhang ◽  
Riccardo Schweizer ◽  
Wakako Tsuji ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Graft Survival ◽  
Vascularized Composite Allotransplantation ◽  
Prolong Graft Survival

scholarly journals Coencapsulation of Target Effector Cells with Mesenchymal Stem Cells Reduces Pericapsular Fibrosis and Improves Graft Survival in a Xenotransplanted Animal Model

2016 ◽  
Vol 25 (7) ◽  
pp. 1299-1317 ◽  
Author(s):  
Vijayaganapathy Vaithilingam ◽  
Margaret D. M. Evans ◽  
Anthony Rowe ◽  
Penelope A. Bean ◽  
Bernard E. Tuch
Keyword(s):  
Stem Cells ◽  
Animal Model ◽  
Mesenchymal Stem Cells ◽  
Graft Survival ◽  
Effector Cells
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