The human complement receptor type 2 (CR2)/CR1 fusion protein TT32, a targeted inhibitor of the classical and alternative pathway C3 convertases, prevents arthritis in active immunization and passive transfer models and acts by CR2-dependent targeting of CR1 regulatory activity

Immunobiology ◽  
2012 ◽  
Vol 217 (11) ◽  
pp. 1210 ◽  
Author(s):  
Michael Holers ◽  
Nirmal Banda ◽  
Gaurav Mehta ◽  
Masha Fridkis-Hareli ◽  
Eran Or ◽  
...  
Keyword(s):  
Fusion Protein ◽  
Alternative Pathway ◽  
Passive Transfer ◽  
Active Immunization ◽  
Receptor Type ◽  
Complement Receptor ◽  
Human Complement ◽  
Regulatory Activity ◽  
Complement Receptor Type

Solution structure of the complex between human complement C3d and full length complement receptor type 2

2008 ◽  
Vol 45 (16) ◽  
pp. 4120
Author(s):  
Keying Li ◽  
Azubuike Okemefuna ◽  
Jayesh Gor ◽  
Jonathan Hannan ◽  
Rengasamy Asokan ◽  
...  
Keyword(s):  
Solution Structure ◽  
Full Length ◽  
Receptor Type ◽  
Complement Receptor ◽  
Human Complement ◽  
Complement Receptor Type

scholarly journals B Cells from Mice Prematurely Expressing Human Complement Receptor Type 2 Are Unresponsive to T-Dependent Antigens

2005 ◽  
Vol 174 (11) ◽  
pp. 6974-6982 ◽  
Author(s):  
Louise Birrell ◽  
Liudmila Kulik ◽  
B. Paul Morgan ◽  
V. Michael Holers ◽  
Kevin J. Marchbank
Keyword(s):  
B Cells ◽  
Receptor Type ◽  
Complement Receptor ◽  
Human Complement ◽  
Complement Receptor Type

Solution Structure of the Complex Formed between Human Complement C3d and Full-length Complement Receptor Type 2

2008 ◽  
Vol 384 (1) ◽  
pp. 137-150 ◽  
Author(s):  
Keying Li ◽  
Azubuike I. Okemefuna ◽  
Jayesh Gor ◽  
Jonathan P. Hannan ◽  
Rengasamy Asokan ◽  
...  
Keyword(s):  
Solution Structure ◽  
Full Length ◽  
Receptor Type ◽  
Complement Receptor ◽  
Human Complement ◽  
Complement Receptor Type
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