Treatment of thymic carcinoma with erlotinib and remarkable disease stabilization for 9 years: A case report

2019 ◽  
Vol 104 (1) ◽  
pp. 239-240
Author(s):  
L. Taniwaki ◽  
S.D. Simon
2010 ◽  
Vol 63 (3) ◽  
pp. 221
Author(s):  
Nu Rhee Hong ◽  
Ki Yeol Lee ◽  
Je Hyeong Kim ◽  
Ki Hwan Jung ◽  
Bo Kyoung Je
Keyword(s):  

2007 ◽  
Vol 68 (2) ◽  
pp. 233-238 ◽  
Author(s):  
Eric M. Thompson ◽  
Michael D. Sather ◽  
Christine A. Reyes ◽  
Douglas J. Long

2021 ◽  
Vol 156 (Supplement_1) ◽  
pp. S42-S42
Author(s):  
A K Abu-Salah ◽  
S Segura ◽  
H Mesa ◽  
H M Cramer

Abstract Introduction/Objective Thyroid carcinoma showing thymus-like differentiation also known as intrathyroidal thymic carcinoma is a rare thyroid neoplasm arising from either an ectopic intrathyroidal thymic tissue or from remnants of thymobranchial pouches. On fine needle aspiration (FNA) its diagnosis can be challenging due to overlapping morphologic features with other aggressive thyroid carcinomas. Methods/Case Report A 31-year-old female consulted for 6-month history of neck swelling and tenderness. Thyroid ultrasound demonstrated a 2.6 x 2.5 x 2.1 cm nodule in the right lobe with punctate calcifications. FNA showed cellular smears composed of loosely cohesive and single basaloid neoplastic cells exhibiting significant cellular and nuclear pleomorphism. Focal squamous differentiation with keratinization was noted on the cell block sections. Immunocytochemical stains showed that the tumor was positive for cytokeratin AE1/AE3, p40, p63, CD117 and CD5 consistent with intrathyroidal thymic carcinoma. The Ki67 proliferative index was approximately 40%. A right thyroidectomy with central neck dissection confirmed the diagnosis and showed a 3.0 cm tumor with invasion into skeletal muscle, lymphovascular invasion and positive lymph nodes. The patient completed adjuvant radiotherapy and remain in remission at 3-months follow-up. Results (if a Case Study enter NA) NA Conclusion Intrathyroidal thymic carcinoma is a rare thyroid neoplasm that frequently shows squamous differentiation and therefore overlaps with papillary thyroid carcinoma with squamous morulae, squamous cell carcinoma and anaplastic carcinoma. The coexpression of squamous markers together with CD5 and CD117 allows the recognition of CASTLE on FNA samples.


2019 ◽  
Vol 10 (10) ◽  
pp. 2031-2034
Author(s):  
Xingguo Yang ◽  
Lei Yu ◽  
Fei Li ◽  
Tao Yu ◽  
Yunfeng Zhang ◽  
...  

2016 ◽  
Vol 17 ◽  
pp. 60-64 ◽  
Author(s):  
Kayo Inoue ◽  
Hiroshi Tsubamoto ◽  
Yusuke Tomogane ◽  
Mariko Kamihigashi ◽  
Hiroaki Shibahara

2019 ◽  
Vol 13 (1) ◽  
pp. 107-110
Author(s):  
Takahiko Akiyama ◽  
Yuji Miyamoto ◽  
Daichi Nomoto ◽  
Yuki Kiyozumi ◽  
Kojiro Eto ◽  
...  

2008 ◽  
Vol 121 (5) ◽  
pp. 478-479
Author(s):  
Chuan-liang PENG ◽  
Xiao-gang ZHAO ◽  
Dong-mei ZHAO ◽  
Xiao-peng DONG
Keyword(s):  

2019 ◽  
Vol 86 (6) ◽  
pp. 357-359
Author(s):  
Shingo Takeuchi ◽  
Naoyuki Yoshino ◽  
Jitsuo Usuda

2016 ◽  
Vol 2 (1) ◽  
Author(s):  
Shuichi Shinohara ◽  
Koji Kuroda ◽  
Taiji Kuwata ◽  
Masaru Takenaka ◽  
Soichi Oka ◽  
...  
Keyword(s):  

2015 ◽  
Vol 9 (4) ◽  
pp. 1715-1718 ◽  
Author(s):  
PING ZHAN ◽  
HAIYAN XIE ◽  
LI-KE YU
Keyword(s):  

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