Characterization of Unconventional Response of Gray Zone Lymphoma to Conventional Radiation Treatment

2012 ◽  
Vol 84 (3) ◽  
pp. S622-S623
Author(s):  
G. Jones ◽  
K. Camphausen ◽  
W. Wyndham ◽  
D. Smart
Keyword(s):  
Radiation Treatment ◽  
Gray Zone ◽  
Gray Zone Lymphoma ◽  
Conventional Radiation

“Gray Zone” Lymphoma on Maxilla: Case Report

2014 ◽  
Vol 117 (2) ◽  
pp. e134
Author(s):  
PAULA VERONA RAGUSA DA SILVA ◽  
GUSTAVO HENRIQUE CAMPOS RODRIGUES ◽  
VICTOR PIANA DE ANDRADE ◽  
ANDRÉ CAROLI ROCHA ◽  
JOSÉ DIVALDO PRADO ◽  
...  
Keyword(s):  
Case Report ◽  
Gray Zone ◽  
Gray Zone Lymphoma

scholarly journals Dose adjusted-EPOCH-R and mediastinal disease may improve outcomes for patients with gray-zone lymphoma

2016 ◽  
Vol 179 (3) ◽  
pp. 503-506 ◽  
Author(s):  
Dai Chihara ◽  
Jason R. Westin ◽  
Roberto N. Miranda ◽  
Chan Y. Cheah ◽  
Yasuhiro Oki ◽  
...  
Keyword(s):  
Gray Zone ◽  
Gray Zone Lymphoma ◽  
Mediastinal Disease

Primary Mediastinal (Thymic) Large B-Cell Lymphoma: A Short Review With Brief Discussion of Mediastinal Gray Zone Lymphoma

2011 ◽  
Vol 135 (3) ◽  
pp. 394-398 ◽  
Author(s):  
Charles Blake Hutchinson ◽  
Endi Wang
Keyword(s):  
B Cell ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Short Review ◽  
Comparative Genomic ◽  
Gray Zone ◽  
Superior Mediastinum ◽  
Gray Zone Lymphoma ◽  
Large B Cell Lymphoma ◽  
Large B Cell

Abstract Primary mediastinal (thymic) large B-cell lymphoma (PMBCL) is a subtype of diffuse large B-cell lymphoma (DLBCL). It commonly presents as a bulky lesion in the anterior-superior mediastinum with symptoms related to local invasion or compression. Microscopic examination typically shows infiltration of medium-large cells surrounded by collagen fibrosis. The neoplastic cells express B-cell markers, and CD30 often shows heterogeneous staining. Comparative genomic hybridization has identified gains in loci of 9p24 and 2p15 as well as Xp11.4-21 and Xq24-26. Amplification of REL and BCL11A at 2p as well as elevated expression of JAK2, PDL1, and PDL2 at 9p has been demonstrated. Nodular sclerosis classic Hodgkin lymphoma needs to be differentiated from PMBCL and cases with overlapped features have been described as mediastinal gray zone lymphoma. Primary mediastinal (thymic) large B-cell lymphoma carries a favorable prognosis in comparison to conventional DLBCL.

RADT-23. RECURRENT OLIGODENDROGLIOMAS AFTER FIRST CHEMO-RADIATION THERAPY RESPONDED REMARKABLY TO RE-RADIATION

2021 ◽  
Vol 23 (Supplement_6) ◽  
pp. vi46-vi46
Author(s):  
Fumi Higuchi ◽  
Takeo Uzuka ◽  
Keisuke Ueki
Keyword(s):  
Radiation Therapy ◽  
Primary Tumor ◽  
Radiation Treatment ◽  
Karnofsky Performance Status ◽  
Performance Status ◽  
Lateral Side ◽  
Who Grade ◽  
Recurrent Tumors ◽  
Conventional Radiation ◽  
Before And After

Abstract Oligodendrogliomas with 1p/19q-codeletion are relatively slow progressive tumors that show good response to chemo-radiation therapy after resection. The median survival is about 15 years regardless of WHO grade, although recurrences are mostly inevitable and there is no standard treatment for recurrence. We experienced 5 oligodendroglioma cases who underwent re-radiation for recurrent tumors after chemo-radiation treatment. We retrospectively investigated those for response to re-radiation, the duration from first radiation to second radiation, and Karnofsky Performance Status (KPS) before and after the re-radiation. Patients were all male; the median radiation dose for primary tumor was 60Gy (54-60Gy), the median age at first radiation was 46 years (35-59), the median duration from the first radiation to re-radiation was 65 months (range 18-116 months), and the median follow-up period after re-radiation was 15 months (1-39 months). In all 5 cases, tumors showed good response to re-radiation. In 3 of the 5 cases, tumor recurred in corpus callosum and/or lateral side of cerebral hemisphere or basal ganglia contiguous with primary tumor sites and were radiated by IMRT (50Gy/25fr) . In 2 cases, tumors recurred around the fourth ventricle and posterior fossa and underwent conventional radiation (54Gy/30fr and 30Gy/10fr). In 2 of the 5 cases, the tumors re-recurred 24 months later after re-radiation, but the KPS were maintained until re-recurrence. For oligodendrogliomas, re-radiation therapy appears to be very effective to recurrent tumors after first chemo-radiation. Although evaluation for longer-term side effects is to be examined, re-radiation appears to be a good option for recurrent oligodendrogliomas after first chemo-radiation therapy.

Characterization of Microbial Fermented Cellulose Porous Foam Prepared by Radiation Treatment

2013 ◽  
Vol 31 (4) ◽  
pp. 302-307 ◽  
Author(s):  
Hui-Jeong Gwon ◽  
◽  
Young Min Shin ◽  
Jong-Bae Choi ◽  
Jong-Young Lim ◽  
...  
Keyword(s):  
Radiation Treatment

Gray Zone Lymphoma Arising in the Neck of a Teenager With a Germline Mutation in TP53

2019 ◽  
Vol 41 (6) ◽  
pp. e405-e408
Author(s):  
Sophie Gatineau-Sailliant ◽  
Karine Turcotte ◽  
Marie-Claude Quintal ◽  
Sophie Turpin ◽  
Josette Champagne ◽  
...  
Keyword(s):  
Germline Mutation ◽  
Gray Zone ◽  
Gray Zone Lymphoma

Mediastinal Gray Zone Lymphoma with Features Intermediate between Classical Hodgkin Lymphoma and Primary Mediastinal B-Cell Lymphoma

2016 ◽  
Vol 136 (3) ◽  
pp. 186-190 ◽  
Author(s):  
Haa-Na Song ◽  
Seok Jin Kim ◽  
Young Hyeh Ko ◽  
Won Seog Kim
Keyword(s):  
B Cell ◽  
Hodgkin Lymphoma ◽  
Systemic Chemotherapy ◽  
Cell Lymphoma ◽  
Progression Free Survival ◽  
B Cell Lymphoma ◽  
Gray Zone ◽  
Bulky Disease ◽  
Gray Zone Lymphoma ◽  
Frontline Therapy

Background: Mediastinal gray zone lymphoma (MGZL) shares clinical characteristics with primary mediastinal B-cell lymphoma (PMBCL) and nodular sclerosing Hodgkin lymphoma (NSHL). However, MGZL is extremely rare, and an appropriate treatment for it has not yet been established. Methods: We retrospectively analyzed 8 patients who were treated with systemic chemotherapy for MGZL between 2007 and 2014. Results: The patients with MGZL were predominantly young and male (median age 26 years), and 62.5% of patients had bulky disease. The overall response rate (ORR) and complete remission (CR) rate were both 75% (6/8) for all treated patients The median overall survival (OS) and progression-free survival (PFS) was 40.7 and 3.9 months, respectively. Most responders (4/6, 66.7%) were treated with R-CHOP (rituximab + cyclophosphamide, hydroxydaunorubicin, Oncovin and prednisolone) as the frontline therapy. The CR rate of patients who received R-CHOP and those who did not was 100% (4/4) and 50% (2/4), respectively. Particularly striking was the finding that the median PFS of patients who received R-CHOP frontline chemotherapy was 11.4 months, which was superior to the median PFS of patients who did not receive R-CHOP. Conclusions: Of the 8 patients with MGZL who were treated with systemic chemotherapy, superior treatment responses were observed in patients who received R-CHOP as the frontline therapy.

Characterization of Crystalline Silicon via XRPD

2004 ◽  
Vol 443-444 ◽  
pp. 83-86
Author(s):  
Giovanni Berti ◽  
U. Bartoli ◽  
G. Basile ◽  
P. Becker ◽  
Andrew N. Fitch
Keyword(s):  
Grain Size ◽  
Polycrystalline Silicon ◽  
Crystalline Silicon ◽  
Crystal Silicon ◽  
Conventional Radiation ◽  
Structural Contribution ◽  
Structural Arrangements

Three blocks of silicon have been crashed in this experiment in order to verify the crashing effects on specimens having distinct original micro-structural arrangements. One of them comes from a rod bar of mono-crystal silicon, two others were from polycrystalline silicon manufactured by two distinct manufacturers with distinct growing process. Several specimens of powders, differing in type and grain size, were obtained by treating these source samples. This paper reports on data collected from synchrotron and conventional radiation and the results show that powders obtained from mono-crystalline silicon provide diffraction profiles, where the structural contribution is smaller than for polycrystalline silicon specimens. The peaks from the 'mono-crystal powder' resulted even narrower than peaks from SRM Silicon 640b by NIST.

Sign in / Sign up

Export Citation Format

Share Document