Outcome of T4 (International Union Against Cancer Staging System, 7th edition) or Recurrent Nasal Cavity and Paranasal Sinus Carcinoma Treated With Proton Beam

2012 ◽  
Vol 83 (2) ◽  
pp. 704-711 ◽  
Author(s):  
Nobuyoshi Fukumitsu ◽  
Toshiyuki Okumura ◽  
Masashi Mizumoto ◽  
Yoshiko Oshiro ◽  
Takayuki Hashimoto ◽  
...  
Keyword(s):  
Nasal Cavity ◽  
Proton Beam ◽  
Paranasal Sinus ◽  
Staging System ◽  
Cancer Staging ◽  
International Union ◽  
7Th Edition ◽  
Paranasal Sinus Carcinoma

Development of Mucosal Thickening after Radiotherapy in Contralateral Sinuses of Patients with Nasal Cavity and/or Paranasal Sinus Carcinoma

2008 ◽  
Vol 117 (11) ◽  
pp. 844-848 ◽  
Author(s):  
Jong Hwan Wang ◽  
Bong-Jae Lee ◽  
Jeong Hyun Lee ◽  
In June Kim ◽  
Yong Ju Jang
Keyword(s):  
Nasal Cavity ◽  
Paranasal Sinus ◽  
Medical Records ◽  
Staging System ◽  
Ct Scans ◽  
Control Group ◽  
Paranasal Sinus Carcinoma ◽  
The Mean ◽  
Mucosal Thickening

Objectives: The aim of this study was to investigate the development of radiotherapy (RT)–induced mucosal thickening (MT) of the contralateral sinuses in patients with nasal cavity and/or paranasal sinus carcinoma. Methods: We retrospectively reviewed the medical records and the initial and follow-up computed tomography (CT) scans of 37 patients with RT and 10 controls without RT. The CT scans were scored on the Lund-Mackay (LM) staging system. Results: Fifteen of the 37 patients had MT before RT, and the mean LM score was 0.68. The MT incidence significantly increased, to 72.9% (p = 0.009), and the LM score significantly increased, to 2.84 (p < 0.001), by 3 months after RT, after which the LM score decreased gradually to 1.73 at 36 months after RT. Four of the 10 controls had MT before treatment, and their mean LM score was 0.7. Their MT incidence and LM score had not changed significantly at 3 months after treatment. The pretreatment LM scores of the patient group and the control group were not significantly different, but their posttreatment LM scores were significantly different at the 3-month follow-up (p = 0.033). Conclusions: Use of RT in patients with nasal cavity and/or paranasal sinus carcinoma may cause a significant increase in the incidence of MT and in the LM scores in all sites of the paranasal sinuses by 3 months after RT, after which the LM score decreases gradually.

Nasal Cavity and Paranasal Sinus Carcinoma

2013 ◽  
pp. 247-257
Author(s):  
Alfred M. Iloreta ◽  
Brett A. Miles
Keyword(s):  
Nasal Cavity ◽  
Paranasal Sinus ◽  
Paranasal Sinus Carcinoma

Introduction of the 7th Edition Eyelid Carcinoma Classification System From the American Joint Committee on Cancer–International Union Against Cancer Staging Manual

2009 ◽  
Vol 133 (8) ◽  
pp. 1256-1261
Author(s):  
Darryl J. Ainbinder ◽  
Bita Esmaeli ◽  
Stephen C. Groo ◽  
Paul T. Finger ◽  
Joseph P. Brooks
Keyword(s):  
Task Force ◽  
Peer Review Process ◽  
Tumor Biology ◽  
Cancer Staging ◽  
Data Sources ◽  
Lymph Node Staging ◽  
Evidence Based ◽  
International Union ◽  
7Th Edition ◽  
American Joint Committee

Abstract Context.—The American Joint Committee on Cancer (AJCC) and the International Union Against Cancer commissioned the Ophthalmic Oncology Task Force to modify and update the ophthalmic chapters of the 7th edition of the AJCC Cancer Staging Manual. Objective.—To review the existing eyelid carcinoma chapter in the 6th edition of the AJCC Cancer Staging Manual for its clinical and research utility and to seek evidence-based revisions with the strongest medical foundation to use in updating the anatomically based TNM cancer staging system manual. Data Sources.—The 4-year Ophthalmic Oncology Task Force consisted of 45 tumor specialists from 10 countries and an extensive internal and external peer review process. The 10-member Carcinoma of the Eyelid team included a diverse group of international authors. The group included extensive representation by clinicians, pathologists, surgeons, radiation therapists, and cancer registrars, all with advanced, ophthalmic cancer–related areas of subspecialty. Data sources included the above expertise applying a worldwide medical literature search, with no discrimination based on language, country of origin, discipline source, specialty source, or surgical practice. Conclusions.—Revisions were made to the TNM classification in areas with the strongest basis in evidence and practical effect. Lymph node staging data were expanded markedly to reflect its significant prognostic value. T3 and T4 were redefined and stage groupings were added that applied current understanding in tumor biology, respected site-specific risk factors, and provided greater correlation with the common language of the overall AJCC Cancer Staging Manual. Evidence-based biomarkers and data-field modifiers were included to capture additional pathologically and clinically substantiated prognostic factors.

Contralateral Maxillary Sinus Lesions in Patients with Nasal Cavity and/or Paranasal Sinus Carcinoma: Analysis of Computed Tomography Findings

2008 ◽  
Vol 117 (12) ◽  
pp. 909-913 ◽  
Author(s):  
Jong Hwan Wang ◽  
Jeong Hyun Lee ◽  
Ju Hee Han ◽  
Bong-Jae Lee ◽  
Yong Ju Jang
Keyword(s):  
Computed Tomography ◽  
Nasal Cavity ◽  
Maxillary Sinus ◽  
Paranasal Sinus ◽  
Tumor Development ◽  
Second Primary ◽  
Ct Analysis ◽  
Paranasal Sinus Carcinoma ◽  
Age Range

Objectives: The incidence of bilateral maxillary sinus carcinoma is very low in patients with primary maxillary sinus carcinoma. However, surgeons should perform careful diagnosis of any contralateral maxillary sinus lesions to avoid missing a second primary maxillary sinus carcinoma. We therefore investigated the computed tomography (CT) findings of the contralateral maxillary sinus in patients with nasal cavity and/or paranasal sinus carcinoma. Methods: Between August 1994 and September 2006, 66 patients (41 male, 25 female; age range, 22 to 85 years; mean age, 56.9 years) with nasal and/or paranasal sinus carcinoma were treated. Preoperative and follow-up CT scans of their contralateral maxillary sinuses were retrospectively reviewed. Results: Of the 66 patients, 26 (39.4%) had rhinosinusitis, 6 (9.1%) had retention cysts, and 33 (50.0%) showed normal findings on CT. One patient (1.5%) had bilateral enhanced mass-like lesions. Both masses were diagnosed histologically as poorly differentiated squamous cell carcinoma. The rhinosinusitis findings included mucoperiosteal thickening, sclerotic bone thickening, hyperdense secretion, and an air-fluid level, in order of decreasing frequency. Twenty-three of the 32 patients with benign lesions were included in the follow-up CT analysis, ranging from 24 to 108 months (mean, 45 months). On the final CT scan, rhinosinusitis was aggravated in 5 of 19 cases and improved in 14 cases, and the size of the retention cyst decreased in 4 cases. During the follow-up period, no definite abnormality suggesting tumor development in the contralateral maxillary sinus was detected. Conclusions: Even though most contralateral maxillary sinus lesions are benign and the incidence of bilateral maxillary sinus carcinoma is very low, second primary maxillary sinus carcinoma should be kept in mind in the differential diagnosis of contralateral maxillary sinus lesions in patients with nasal cavity and/or paranasal sinus carcinoma.

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