Patient Specific Dosimetry and Quality Assurance for an Active Uniform Scanning Proton Beam

Author(s):  
A.E. Mascia ◽  
M. Wolanski ◽  
R. Jesseph ◽  
D. Nichiporov
Author(s):  
Peter Obid ◽  
Tamás Fekete ◽  
Philipp Drees ◽  
Daniel Haschtmann ◽  
Frank Kleinstück ◽  
...  

Abstract Purpose Chordomas are rare tumors with an annual incidence of approximately one per million. Chordomas rarely metastasize but show a high local recurrence rate. Therefore, these patients present a major clinical challenge, and there is a paucity of the literature regarding the outcome after revision surgery of cervical spine chordomas. Available studies suggest a significantly worse outcome in revision scenarios. The purpose of this study is to analyze the survival rate, and complications of patients that underwent revision surgery for local recurrence or incomplete resection of chordoma at the craniocervical junction or at the cervical spine. Methods 24 consecutive patients that underwent revision surgery for cervical spine chordoma remnants or recurrence at a single center were reviewed retrospectively. We analyzed patient-specific surgical treatment strategies, complications, and outcome. Kaplan–Meier estimator was used to analyze five-year overall survival. Results Gross total resection was achieved in 17 cases. Seven patients developed dehiscence of the pharyngeal wall, being the most common long-term complication. No instability was observed. Postoperatively, four patients received proton beam radiotherapy and 12 patients had combined photon and proton beam radiotherapy. The five-year overall survival rate was 72.6%. Conclusion With thorough preoperative planning, appropriate surgical techniques, and the addition of adjuvant radiotherapy, results similar to those in primary surgery can be achieved.


2018 ◽  
Vol 56 ◽  
pp. 67-68 ◽  
Author(s):  
M. Zani ◽  
S. Calusi ◽  
R. Doro ◽  
N. Bellosi ◽  
M. Cassinelli ◽  
...  

2016 ◽  
Author(s):  
◽  
Jason Stanford

[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Advance treatment techniques, such as IMRT and dynamic conformal arc delivery, are novel radiation treatment procedures at the forefront of accurate and precise radiotherapy. However, the risk of suboptimal treatment resulting in injury is far greater with these techniques due to their complexity. An in vivo quality assurance system is the most appropriate validation of the delivered dose to the patient from these techniques. The intent of this research is to propose an in vivo dosimetry quality assurance procedure using radiochromic film. This research proved that radiochromic in vivo dosimetry is a viable method of detecting spatial patient specific errors in radiotherapy; however, the process is time consuming and not sensitive enough for dosimetric errors associated with weight change. Although time consuming, in vivo radiochromic dosimetry is an attractive alternative for small cancer centers and developing countries without the large startup capital to acquire the electronic portal imaging device necessary for EPID in vivo dosimetry.


2018 ◽  
Vol 52 ◽  
pp. 137-138
Author(s):  
Luca Leandro Vigna ◽  
Ashenafi Kumela Rikitu ◽  
Eleonora Monès ◽  
Federica Puricelli ◽  
Chiara Secco ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document